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Actinorhodin Polyketide Ketoreductase, act KR, with NADP bound
Descriptor:	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative ketoacyl reductase
Authors:	Korman, T.P, Hill, J.A, Vu, T.N.
Deposit date:	2004-08-13
Release date:	2004-12-14
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity Biochemistry, 43, 2004

Actinorhodin Polyketide Ketoreductase, with NADPH bound
Descriptor:	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative ketoacyl reductase
Authors:	Korman, T.P, Hill, J.A, Vu, T.N.
Deposit date:	2004-08-13
Release date:	2004-12-14
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity Biochemistry, 43, 2004

Actinorhodin Polyketide Ketoreductase with NADP and the Inhibitor Isoniazid bound
Descriptor:	4-(DIAZENYLCARBONYL)PYRIDINE, ACTINORHODIN POLYKETIDE KETOREDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:	Korman, T.P, Hill, J.A, Vu, T.N, Tsai, S.C.
Deposit date:	2004-10-13
Release date:	2005-09-27
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (2.71 Å)
Cite:	Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity. Biochemistry, 43, 2004

Crystal structure of the aromatase/cyclase domain of TcmN from Streptomyces glaucescens
Descriptor:	Multifunctional cyclase-dehydratase-3-O-methyl transferase tcmN
Authors:	Ames, B.D, Korman, T.P, Vu, T.N, Tsai, S.C.
Deposit date:	2007-09-26
Release date:	2008-04-22
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Crystal structure and functional analysis of tetracenomycin ARO/CYC: implications for cyclization specificity of aromatic polyketides. Proc.Natl.Acad.Sci.Usa, 105, 2008