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4A49
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STRUCTURE OF PHOSPHOTYR371-C-CBL-UBCH5B COMPLEX
Descriptor:E3 ubiquitin-protein ligase CBL, Ubiquitin-conjugating enzyme E2 D2, ZINC ION, ...
Authors:Dou, H., Buetow, L., Hock, A., Sibbet, G.J., Vousden, K.H., Huang, D.T.
Deposit date:2011-10-07
Release date:2012-01-25
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.214 Å)
Cite:Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl.
Nat. Struct. Mol. Biol., 19, 2012
4A4B
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STRUCTURE OF MODIFIED PHOSPHOTYR371-C-CBL-UBCH5B-ZAP-70 COMPLEX
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, UBIQUITIN-CONJUGATING ENZYME E2 D2, ...
Authors:Dou, H., Buetow, L., Hock, A., Sibbet, G.J., Vousden, K.H., Huang, D.T.
Deposit date:2011-10-08
Release date:2012-01-25
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl
Nat.Struct.Mol.Biol., 19, 2012
4A4C
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STRUCTURE OF PHOSPHOTYR371-C-CBL-UBCH5B-ZAP-70 COMPLEX
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, UBIQUITIN-CONJUGATING ENZYME E2 D2, ...
Authors:Dou, H., Buetow, L., Hock, A., Sibbet, G.J., Vousden, K.H., Huang, D.T.
Deposit date:2011-10-08
Release date:2012-01-25
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl
Nat.Struct.Mol.Biol., 19, 2012
4B2D
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HUMAN PKM2 WITH L-SERINE AND FBP BOUND.
Descriptor:PYRUVATE KINASE ISOZYMES M1/M2, SERINE, BETA-FRUCTOSE-1,6-DIPHOSPHATE, ...
Authors:Chaneton, B., Hillmann, P., Zheng, L., Martin, A.C.L., Maddocks, O.D.K., Chokkathukalam, A., Coyle, J.E., Jankevics, A., Holding, F.P., Vousden, K.H., Frezza, C., O'Reilly, M., Gottlieb, E.
Deposit date:2012-07-13
Release date:2012-10-10
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Serine is a natural ligand and allosteric activator of pyruvate kinase M2.
Nature, 491, 2012
2Y1M
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STRUCTURE OF NATIVE C-CBL
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE, ZINC ION, CALCIUM ION
Authors:Dou, H., Sibbet, G.J., Huang, D.T.
Deposit date:2010-12-08
Release date:2012-01-18
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl.
Nat.Struct.Mol.Biol., 19, 2012
2Y1N
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STRUCTURE OF C-CBL-ZAP-70 PEPTIDE COMPLEX
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE, TYROSINE-PROTEIN KINASE ZAP-70 ZAP-70,70 KDA ZETA-ASSOCIATED PROTEIN, SYK-RELATED TYROSINE KINASE, ...
Authors:Dou, H., Sibbet, G.J., Huang, D.T.
Deposit date:2010-12-08
Release date:2012-01-18
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl.
Nat.Struct.Mol.Biol., 19, 2012
5MNJ
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STRUCTURE OF MDM2-MDMX-UBCH5B-UBIQUITIN COMPLEX
Descriptor:Ubiquitin-conjugating enzyme E2 D2, Polyubiquitin-B, E3 ubiquitin-protein ligase Mdm2, ...
Authors:Klejnot, M., Huang, D.T.
Deposit date:2016-12-13
Release date:2017-05-31
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.
Nat. Struct. Mol. Biol., 24, 2017
6SQO
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CRYSTAL STRUCTURE OF HUMAN MDM2 RING DOMAIN HOMODIMER BOUND TO UBCH5B-UB
Descriptor:E3 ubiquitin-protein ligase Mdm2, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin-40S ribosomal protein S27a, ...
Authors:Magnussen, H.M., Ahmed, S.F., Huang, D.T.
Deposit date:2019-09-04
Release date:2020-05-06
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
6SQP
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CRYSTAL STRUCTURE OF CAT MDM2-S429E RING DOMAIN HOMODIMER
Descriptor:E3 ubiquitin-protein ligase Mdm2, ZINC ION, CHLORIDE ION, ...
Authors:Magnussen, H.M., Ahmed, S.F., Huang, D.T.
Deposit date:2019-09-04
Release date:2020-05-06
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
6SQR
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CRYSTAL STRUCTURE OF CAT MDM2-S429E RING DOMAIN BOUND TO UBCH5B-UB
Descriptor:E3 ubiquitin-protein ligase Mdm2, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin-40S ribosomal protein S27a, ...
Authors:Magnussen, H.M., Ahmed, S.F., Huang, D.T.
Deposit date:2019-09-04
Release date:2020-05-06
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
6SQS
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CRYSTAL STRUCTURE OF CAT PHOSPHO-SER429 MDM2 RING DOMAIN BOUND TO UBCH5B-UB
Descriptor:E3 ubiquitin-protein ligase Mdm2, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin-40S ribosomal protein S27a, ...
Authors:Magnussen, H.M., Ahmed, S.F., Huang, D.T.
Deposit date:2019-09-04
Release date:2020-05-06
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020