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4NYZ
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THE EMCV 3DPOL STRUCTURE WITH ALTERED MOTIF A CONFORMATION AT 2.15A RESOLUTION
Descriptor:Genome polyprotein, GLUTAMINE, MAGNESIUM ION, ...
Authors:Vives-adrian, L., Lujan, C., Ferrer-orta, C., Verdaguer, N.
Deposit date:2013-12-11
Release date:2014-03-19
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site
J.Virol., 88, 2014
4NZ0
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THE EMCV 3DPOL STRUCTURE AT 2.8A RESOLUTION
Descriptor:Genome polyprotein, GLYCEROL, CHLORIDE ION
Authors:Vives-adrian, L., Ferrer-orta, C., Verdaguer, N.
Deposit date:2013-12-11
Release date:2014-03-19
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site
J.Virol., 88, 2014
4WZN
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CRYSTAL STRUCTURE OF THE 2B PROTEIN SOLUBLE DOMAIN FROM HEPATITIS A VIRUS
Descriptor:Genome polyprotein, GLYCEROL
Authors:Garriga, D., Vives-Adrian, L., Buxaderas, M., Ferreira-da-Silva, F., Almeida, B., Macedo-Ribeiro, S., Pereira, P.J., Verdaguer, N.
Deposit date:2014-11-20
Release date:2015-01-28
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for Host Membrane Remodeling Induced by Protein 2B of Hepatitis A Virus.
J.Virol., 89, 2015
4Y2A
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CRYSTAL STRUCTURE OF COXSACKIE VIRUS B3 3D POLYMERASE IN COMPLEX WITH GPC-N114 INHIBITOR
Descriptor:3D polymerase, 2,2'-[(4-chlorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), SULFATE ION, ...
Authors:Vives-Adrian, L., Ferrer-Orta, C., Verdaguer, N.
Deposit date:2015-02-09
Release date:2015-04-01
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4Y34
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CRYSTAL STRUCTURE OF COXSACKIEVIRUS B3 3D POLYMERASE IN COMPLEX WITH GPC-N143
Descriptor:3D polymerase, 2,2'-[(4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), SULFATE ION, ...
Authors:Vives-Adrian, L., Ferrer-Orta, C., Cerdaguer, N.
Deposit date:2015-02-10
Release date:2015-04-01
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4L3B
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X-RAY STRUCTURE OF THE HRV2 A PARTICLE UNCOATING INTERMEDIATE
Descriptor:Protein VP1, Protein VP2, Protein VP3
Authors:Vives-Adrian, L., Querol-Audi, J., Garriga, D., Pous, J., Verdaguer, N.
Deposit date:2013-06-05
Release date:2013-11-27
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:Uncoating of common cold virus is preceded by RNA switching as determined by X-ray and cryo-EM analyses of the subviral A-particle.
Proc.Natl.Acad.Sci.USA, 110, 2013
4Y2C
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M300V 3D POLYMERASE MUTANT OF EMCV
Descriptor:Genome polyprotein, GLYCEROL
Authors:Verdaguer, N., Ferrer-Orta, C., Vives-Adrian, L.
Deposit date:2015-02-09
Release date:2015-04-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4Y3C
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I304V 3D POLYMERASE MUTANT OF EMCV
Descriptor:3D polymerase, GLYCEROL, CHLORIDE ION
Authors:Verdaguer, N., Ferrer-Orta, C., Vives-Adrian, L.
Deposit date:2015-02-10
Release date:2015-04-01
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015