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4D2G
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BU of 4d2g by Molmil
Crystal structure of human PCNA in complex with p15 peptide
Descriptor: P15, PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:DeBiasio, A, Ibanez, A, Mortuza, G, Molina, R, Cordeiro, T.N, Castillo, F, Villate, M, Merino, N, Lelli, M, Diercks, T, Luque, I, Bernardo, P, Montoya, G, Blanco, F.J.
Deposit date:2014-05-09
Release date:2015-03-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
Nat.Commun., 6, 2015
4AFL
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BU of 4afl by Molmil
The crystal structure of the ING4 dimerization domain reveals the functional organization of the ING family of chromatin binding proteins.
Descriptor: INHIBITOR OF GROWTH PROTEIN 4
Authors:Culurgioni, S, Munoz, I.G, Moreno, A, Palacios, A, Villate, M, Palmero, I, Montoya, G, Blanco, F.J.
Deposit date:2012-01-19
Release date:2012-02-22
Last modified:2012-07-11
Method:X-RAY DIFFRACTION (2.275 Å)
Cite:Crystal Structure of Inhibitor of Growth 4 (Ing4) Dimerization Domain Reveals Functional Organization of Ing Family of Chromatin-Binding Proteins.
J.Biol.Chem., 287, 2012
2XAL
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BU of 2xal by Molmil
Lead derivative of Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with ADP and IP6.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, INOSITOL-PENTAKISPHOSPHATE 2-KINASE, ...
Authors:Gonzalez, B, Banos-Sanz, J.I, Villate, M, Brearley, C.A, Sanz-Aparicio, J.
Deposit date:2010-03-31
Release date:2010-05-19
Last modified:2020-10-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase is a Distant Ipk Member with a Singular Inositide Binding Site for Axial 2-Oh Recognition.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XAM
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BU of 2xam by Molmil
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with ADP and IP6.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, INOSITOL-PENTAKISPHOSPHATE 2-KINASE, ...
Authors:Gonzalez, B, Banos-Sanz, J.I, Villate, M, Brearley, C.A, Sanz-Aparicio, J.
Deposit date:2010-03-31
Release date:2010-05-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase is a Distant Ipk Member with a Singular Inositide Binding Site for Axial 2-Oh Recognition.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XE0
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BU of 2xe0 by Molmil
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Descriptor: 24MER DNA, ACETATE ION, I-CREI V2V3 VARIANT, ...
Authors:Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Redondo, P, Villate, M, Merino, N, Marenchino, M, D'Abramo, M, Gervasio, F.L, Grizot, S, Daboussi, F, Smith, J, Chion-Sotine, I, Paques, F, Duchateau, P, Alibes, A, Stricher, F, Serrano, L, Blanco, F.J, Montoya, G.
Deposit date:2010-05-10
Release date:2010-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Molecular Basis of Engineered Meganuclease Targeting of the Endogenous Human Rag1 Locus
Nucleic Acids Res., 39, 2011
2XAR
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BU of 2xar by Molmil
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with IP6.
Descriptor: INOSITOL HEXAKISPHOSPHATE, INOSITOL-PENTAKISPHOSPHATE 2-KINASE, ZINC ION
Authors:Gonzalez, B, Banos-Sanz, J.I, Villate, M, Brearley, C.A, Sanz-Aparicio, J.
Deposit date:2010-03-31
Release date:2010-05-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase is a Distant Ipk Member with a Singular Inositide Binding Site for Axial 2-Oh Recognition.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XAO
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BU of 2xao by Molmil
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with IP5
Descriptor: INOSITOL-PENTAKISPHOSPHATE 2-KINASE, MYO-INOSITOL-(1,3,4,5,6)-PENTAKISPHOSPHATE, ZINC ION
Authors:Gonzalez, B, Banos-Sanz, J.I, Villate, M, Brearley, C.A, Sanz-Aparicio, J.
Deposit date:2010-03-31
Release date:2010-05-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase is a Distant Ipk Member with a Singular Inositide Binding Site for Axial 2-Oh Recognition.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XAN
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BU of 2xan by Molmil
inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with AMP PNP and IP5
Descriptor: INOSITOL-PENTAKISPHOSPHATE 2-KINASE, MAGNESIUM ION, MYO-INOSITOL-(1,3,4,5,6)-PENTAKISPHOSPHATE, ...
Authors:Gonzalez, B, Banos-Sanz, J.I, Villate, M, Brearley, C.A, Sanz-Aparicio, J.
Deposit date:2010-03-31
Release date:2010-05-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase is a Distant Ipk Member with a Singular Inositide Binding Site for Axial 2-Oh Recognition.
Proc.Natl.Acad.Sci.USA, 107, 2010
5A77
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BU of 5a77 by Molmil
Crystal structure of the homing endonuclease I-CvuI in complex with I- CreI target (C1221) in the presence of 2 mM Mg revealing DNA cleaved
Descriptor: 10MER DNA, 5'-D(*GP*AP*CP*GP*TP*TP*TP*TP* GP*AP*DGP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3', 14MER DNA, ...
Authors:Molina, R, Redondo, P, LopezMendez, B, Villate, M, Merino, N, Blanco, F.J, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G.
Deposit date:2015-07-03
Release date:2015-09-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Homing Endonuclease I-Cvui Provides a New Template for Genome Modification
J.Biol.Chem., 290, 2015
5A74
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BU of 5a74 by Molmil
Crystal structure of the homing endonuclease I-CvuI in complex with its target (Sro1.3) in the presence of 2 mM Mn
Descriptor: 10MER DNA, 5'-D(*GP*AP*CP*GP*TP*TP*CP*TP*GP*AP)-3', 14MER DNA, ...
Authors:Molina, R, Redondo, P, LopezMendez, B, Villate, M, Merino, N, Blanco, F.J, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G.
Deposit date:2015-07-02
Release date:2015-09-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Homing Endonuclease I-Cvui Provides a New Template for Genome Modification
J.Biol.Chem., 290, 2015
5A78
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BU of 5a78 by Molmil
Crystal structure of the homing endonuclease I-CvuI in complex with I- CreI target (C1221) in the presence of 2 mM Mg revealing DNA not cleaved
Descriptor: 24MER DNA, 5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP *CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3', DNA ENDONUCLEASE I-CVUI, ...
Authors:Molina, R, Redondo, P, LopezMendez, B, Villate, M, Merino, N, Blanco, F.J, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G.
Deposit date:2015-07-03
Release date:2015-09-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Homing Endonuclease I-Cvui Provides a New Template for Genome Modification
J.Biol.Chem., 290, 2015
5A0M
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BU of 5a0m by Molmil
THE CRYSTAL STRUCTURE OF I-SCEI IN COMPLEX WITH ITS TARGET DNA IN THE PRESENCE OF MN
Descriptor: 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP)-3', 5'-D(*CP*AP*GP*GP*GP*TP*AP*AP*TP*AP*CP)-3', 5'-D(*CP*CP*CP*TP*AP*GP*CP*GP*TP)-3', ...
Authors:Prieto, J, Redondo, P, Merino, N, Villate, M, Blanco, F.J, Molina, R.
Deposit date:2015-04-21
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the I-Scei Nuclease Complexed with its DsDNA Target and Three Catalytic Metal Ions.
Acta Crystallogr.,Sect.F, 72, 2016
5A72
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BU of 5a72 by Molmil
Crystal structure of the homing endonuclease I-CvuI in complex with its target (Sro1.3) in the presence of 2 mM Ca
Descriptor: 24MER DNA, 5'-D(*DTP*CP*AP*GP*AP*AP*CP*GP*TP*CP*GP*TP*AP *DCP*GP*AP*CP*GP*TP*TP*CP*TP*GP*A)-3', CALCIUM ION, ...
Authors:Molina, R, Redondo, P, LopezMendez, B, Villate, M, Merino, N, Blanco, F.J, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G.
Deposit date:2015-07-02
Release date:2015-09-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Homing Endonuclease I-Cvui Provides a New Template for Genome Modification
J.Biol.Chem., 290, 2015
5ME8
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BU of 5me8 by Molmil
N-terminal domain of the human tumor suppressor ING5
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, Inhibitor of growth protein 5
Authors:Roversi, P, Blanco, F.J, Rojas, A.L, Buitrago, J.A.R.
Deposit date:2016-11-14
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.
J.Mol.Biol., 431, 2019
5MTO
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BU of 5mto by Molmil
N-terminal domain of the human tumor suppressor ING5 C19S mutant
Descriptor: Inhibitor of growth protein 5, SODIUM ION, SULFATE ION
Authors:Ormaza, G, Buitrago, J.A.R, Roversi, P, Rojas, A.L, Blanco, F.J.
Deposit date:2017-01-10
Release date:2018-02-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.
J.Mol.Biol., 431, 2019
3MXA
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BU of 3mxa by Molmil
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Descriptor: DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*C)-3'), DNA (5'-D(P*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ...
Authors:Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Montoya, G.
Deposit date:2010-05-07
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Nucleic Acids Res., 39, 2011
3MX9
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BU of 3mx9 by Molmil
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Descriptor: CALCIUM ION, DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*GP*AP*GP*AP*AP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*CP*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ...
Authors:Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Montoya, G.
Deposit date:2010-05-07
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Nucleic Acids Res., 39, 2011
3MXB
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BU of 3mxb by Molmil
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Descriptor: CALCIUM ION, DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*GP*AP*GP*AP*AP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*CP*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ...
Authors:Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Montoya, G.
Deposit date:2010-05-07
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Nucleic Acids Res., 39, 2011
6EHT
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BU of 6eht by Molmil
Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme
Descriptor: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), PCNA-associated factor, ...
Authors:De March, M, Barrera-Vilarmau, S, Mentegari, E, Merino, N, Bressan, E, Maga, G, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
Deposit date:2017-09-15
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
6GIS
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BU of 6gis by Molmil
Structural basis of human clamp sliding on DNA
Descriptor: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), Proliferating cell nuclear antigen
Authors:De March, M, Merino, N, Barrera-Vilarmau, S, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
Deposit date:2018-05-15
Release date:2018-05-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural basis of human PCNA sliding on DNA.
Nat Commun, 8, 2017
4ZTD
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BU of 4ztd by Molmil
Crystal Structure of Human PCNA in complex with a TRAIP peptide
Descriptor: ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen
Authors:Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A.
Deposit date:2015-05-14
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.
J.Cell Biol., 212, 2016

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