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2IB1
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BU of 2ib1 by Molmil
Solution structure of p45 Death Domain
Descriptor: Death domain containing membrane protein NRADD
Authors:Vilar, M, Sung, T.C, Lee, K.F, Riek, R.
Deposit date:2006-09-08
Release date:2007-10-23
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution Structure of p45 death domain
To be Published
7O05
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BU of 7o05 by Molmil
Crystal structure of SARS-CoV-2 N-CTD
Descriptor: Nucleoprotein
Authors:Ciges-Tomas, J.R, Vilar, M.
Deposit date:2021-03-25
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Identification of a guanine-specific pocket in the protein N of SARS-CoV-2.
Commun Biol, 5, 2022
7O36
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BU of 7o36 by Molmil
Crystal Structure of SARS-CoV-2 N-CTD in complex with GTP (II)
Descriptor: GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, Nucleoprotein
Authors:Ciges-Tomas, J.R, Vilar, M.
Deposit date:2021-04-01
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a guanine-specific pocket in the protein N of SARS-CoV-2.
Commun Biol, 5, 2022
7O35
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BU of 7o35 by Molmil
Crystal Structure of SARS-CoV-2 N-CTD in complex with GTP (I)
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Nucleoprotein
Authors:Ciges-Tomas, J.R, Vilar, M.
Deposit date:2021-04-01
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification of a guanine-specific pocket in the protein N of SARS-CoV-2.
Commun Biol, 5, 2022
2Q9M
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BU of 2q9m by Molmil
4-Substituted Trinems as Broad Spectrum-Lactamase Inhibitors: Structure-based Design, Synthesis and Biological Activity
Descriptor: (1R,4S,7AS)-1-(1-FORMYLPROP-1-EN-1-YL)-4-METHOXY-2,4,5,6,7,7A-HEXAHYDRO-1H-ISOINDOLE-3-CARBOXYLIC ACID, Beta-lactamase
Authors:Plantan, I, Selic, L, Mesar, T, Stefanic Anderluh, P, Oblak, M, Prezelj, A, Hesse, L, Andrejasic, M, Vilar, M, Turk, D, Kocijan, A, Prevec, T, Vilfan, G, Kocjan, D, Copar, A, Urleb, U, Solmajer, T.
Deposit date:2007-06-13
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:4-Substituted Trinems as Broad Spectrum beta-Lactamase Inhibitors: Structure-Based Design, Synthesis, and Biological Activity
J.Med.Chem., 50, 2007
2Q9N
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BU of 2q9n by Molmil
4-Substituted Trinems as Broad Spectrum-Lactamase Inhibitors: Structure-based Design, Synthesis and Biological Activity
Descriptor: (1S,4R,7AR)-4-BUTOXY-1-[(1R)-1-FORMYLPROPYL]-2,4,5,6,7,7A-HEXAHYDRO-1H-ISOINDOLE-3-CARBOXYLIC ACID, Beta-lactamase
Authors:Plantan, I, Selic, L, Mesar, T, Stefanic Anderluh, P, Oblak, M, Prezelj, A, Hesse, L, Andrejasic, M, Vilar, M, Turk, D, Kocijan, A, Prevec, T, Vilfan, G, Kocjan, D, Copar, A, Urleb, U, Solmajer, T.
Deposit date:2007-06-13
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:4-Substituted Trinems as Broad Spectrum beta-Lactamase Inhibitors: Structure-Based Design, Synthesis, and Biological Activity
J.Med.Chem., 50, 2007
8PBS
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BU of 8pbs by Molmil
Mutant K1482M of the dihydroorotase domain of human CAD protein in apo form
Descriptor: CAD protein, FORMIC ACID, GLYCEROL, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBT
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BU of 8pbt by Molmil
Mutant K1482M of the dihydroorotase domain of human CAD protein bound to the substrate dihydroorotate
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBR
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BU of 8pbr by Molmil
Mutant R1475Q of the dihydroorotase domain of human CAD protein in apo form
Descriptor: CAD protein, FORMIC ACID, ZINC ION
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBG
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BU of 8pbg by Molmil
Mutant K1556T of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBH
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BU of 8pbh by Molmil
Mutant R1617Q of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBN
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BU of 8pbn by Molmil
Mutant R1789Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBU
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BU of 8pbu by Molmil
Mutant K1482M of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBE
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BU of 8pbe by Molmil
Mutant K1556T of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBM
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BU of 8pbm by Molmil
Mutant R1789Q of the dihydroorotase domain of human CAD protein bound to the substrate dihydroorotate
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBJ
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BU of 8pbj by Molmil
Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
Descriptor: CAD protein, FORMIC ACID, GLYCEROL, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBK
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BU of 8pbk by Molmil
Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBP
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BU of 8pbp by Molmil
Mutant R1785C of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBQ
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BU of 8pbq by Molmil
Mutant R1810Q of the dihydroorotase domain of human CAD protein bound to the substrates
Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBI
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BU of 8pbi by Molmil
Mutant R1617Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
2MJO
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BU of 2mjo by Molmil
NMR structure of p75 transmembrane domain C257A mutant in DPC micelles
Descriptor: Tumor necrosis factor receptor superfamily member 16
Authors:Nadezhdin, K, Arseniev, A, Goncharuk, S, Mineev, K.
Deposit date:2014-01-15
Release date:2015-01-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis of p75 Transmembrane Domain Dimerization.
J. Biol. Chem., 291, 2016
2MIC
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BU of 2mic by Molmil
NMR structure of p75 transmembrane domain in DPC micelles
Descriptor: Tumor necrosis factor receptor superfamily member 16
Authors:Nadezhdin, K, Arseniev, A, Goncharuk, S, Mineev, K.
Deposit date:2013-12-12
Release date:2014-12-24
Last modified:2017-09-06
Method:SOLUTION NMR
Cite:Structural Basis of p75 Transmembrane Domain Dimerization.
J. Biol. Chem., 291, 2016
2N90
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BU of 2n90 by Molmil
TrkA transmembrane domain NMR structure in DPC micelles
Descriptor: High affinity nerve growth factor receptor
Authors:Nadezhdin, K, Goncharuk, S, Arseniev, A.
Deposit date:2015-10-29
Release date:2016-11-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of the transmembrane domain dimerization and rotation in the activation mechanism of the TRKA receptor by nerve growth factor.
J.Biol.Chem., 295, 2020

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