Author results

2C5W
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PENICILLIN-BINDING PROTEIN 1A (PBP-1A) ACYL-ENZYME COMPLEX (CEFOTAXIME) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:PENICILLIN-BINDING PROTEIN 1A, ZINC ION, CHLORIDE ION, ...
Authors:Contreras-Martel, C., Job, V., Di Guilmi, A.-M., Vernet, T., Dideberg, O., Dessen, A.
Deposit date:2005-11-02
Release date:2005-12-07
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure of Penicillin-Binding Protein 1A (Pbp1A) Reveals a Mutational Hotspot Implicated in Beta-Lactam Resistance in Streptococcus Pneumoniae.
J.Mol.Biol., 355, 2006
2C6W
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PENICILLIN-BINDING PROTEIN 1A (PBP-1A) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:PENICILLIN-BINDING PROTEIN 1A, ZINC ION, CHLORIDE ION
Authors:Contreras-Martel, C., Job, V., Di Guilmi, A.-M., Vernet, T., Dideberg, O., Dessen, A.
Deposit date:2005-11-14
Release date:2005-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal Structure of Penicillin-Binding Protein 1A (Pbp1A) Reveals a Mutational Hotspot Implicated in Beta-Lactam Resistance in Streptococcus Pneumoniae.
J.Mol.Biol., 355, 2006
5MKC
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CRYSTAL STRUCTURE OF THE RRGA JO.IN COMPLEX
Descriptor:Cell wall surface anchor family protein (Jo),Cell wall surface anchor family protein (In), SULFATE ION, NICKEL (II) ION, ...
Authors:Bonnet, J., Cartannaz, J., Tourcier, G., Contreras-Martel, C., Kleman, J.P., Fenel, D., Schoehn, G., Morlot, C., Vernet, T., Di Guilmi, A.M.
Deposit date:2016-12-03
Release date:2017-03-15
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Autocatalytic association of proteins by covalent bond formation: a Bio Molecular Welding toolbox derived from a bacterial adhesin.
Sci Rep, 7, 2017
1RP5
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PBP2X FROM STREPTOCOCCUS PNEUMONIAE STRAIN 5259 WITH REDUCED SUSCEPTIBILITY TO BETA-LACTAM ANTIBIOTICS
Descriptor:penicillin-binding protein 2x, SULFATE ION
Authors:Pernot, L., Chesnel, L., Legouellec, A., Croize, J., Vernet, T., Dideberg, O., Dessen, A.
Deposit date:2003-12-03
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics.
J.Biol.Chem., 279, 2004
3ZFJ
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N-TERMINAL DOMAIN OF PNEUMOCOCCAL PHTD PROTEIN WITH BOUND ZN(II)
Descriptor:PNEUMOCOCCAL HISTIDINE TRIAD PROTEIN D, ZINC ION
Authors:Bersch, B., Bougault, C., Favier, A., Gabel, F., Roux, L., Vernet, T., Durmort, C.
Deposit date:2012-12-11
Release date:2013-11-20
Last modified:2013-12-18
Method:SOLUTION NMR
Cite:New Insights Into Histidine Triad Proteins: Solution Structure of a Streptococcus Pneumoniae Phtd Domain and Zinc Transfer to Adcaii.
Plos One, 8, 2013
2W1J
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CRYSTAL STRUCTURE OF SORTASE C-1 (SRTC-1) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:PUTATIVE SORTASE, GLYCEROL
Authors:Manzano, C., Contreras-Martel, C., El Mortaji, L., Izore, T., Fenel, D., Vernet, T., Schoehn, G., Di Guilmi, A.M., Dessen, A.
Deposit date:2008-10-17
Release date:2008-12-23
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Sortase-Mediated Pilus Fiber Biogenesis in Streptococcus Pneumoniae.
Structure, 16, 2008
2W1K
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CRYSTAL STRUCTURE OF SORTASE C-3 (SRTC-3) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:PUTATIVE SORTASE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Manzano, C., Contreras-Martel, C., El Mortaji, L., Izore, T., Fenel, D., Vernet, T., Schoehn, G., Di Guilmi, A.M., Dessen, A.
Deposit date:2008-10-17
Release date:2008-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Sortase-Mediated Pilus Fiber Biogenesis in Streptococcus Pneumoniae.
Structure, 16, 2008
2WW8
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STRUCTURE OF THE PILUS ADHESIN (RRGA) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:CELL WALL SURFACE ANCHOR FAMILY PROTEIN, MAGNESIUM ION, CALCIUM ION, ...
Authors:Izore, T., Contreras-Martel, C., El-Mortaji, L., Manzano, C., Terrasse, R., Vernet, T., Di-Guilmi, A.M., Dessen, A.
Deposit date:2009-10-22
Release date:2010-01-19
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of Host Cell Recognition by the Pilus Adhesin from Streptococcus Pneumoniae
Structure, 18, 2010
4BH5
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LYTM DOMAIN OF ENVC, AN ACTIVATOR OF CELL WALL AMIDASES IN ESCHERICHIA COLI
Descriptor:MUREIN HYDROLASE ACTIVATOR ENVC, IODIDE ION, CHLORIDE ION, ...
Authors:Morlot, C., Peters, N.T., Yang, D.C., Uehara, T., Vernet, T., Bernhardt, T.G.
Deposit date:2013-03-29
Release date:2013-07-03
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structure-Function Analysis of the Lytm Domain of Envc, an Activator of Cell Wall Remodeling at the Escherichia Coli Division Site.
Mol.Microbiol., 89, 2013
1PYY
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DOUBLE MUTANT PBP2X T338A/M339F FROM STREPTOCOCCUS PNEUMONIAE STRAIN R6 AT 2.4 A RESOLUTION
Descriptor:Penicillin-binding protein 2X, SULFATE ION, N-OCTANOYLSUCROSE, ...
Authors:Chesnel, L., Pernot, L., Lemaire, D., Champelovier, D., Croize, J., Dideberg, O., Vernet, T., Zapun, A.
Deposit date:2003-07-09
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:The Structural Modifications Induced by the M339F Substitution in PBP2x from Streptococcus pneumoniae Further Decreases the Susceptibility to beta-Lactams of Resistant Strains
J.Biol.Chem., 278, 2003
1XP4
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CRYSTAL STRUCTURE OF A PEPTIDOGLYCAN SYNTHESIS REGULATORY FACTOR (PBP3) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:D-alanyl-D-alanine carboxypeptidase, SULFATE ION, IODIDE ION
Authors:Morlot, C., Pernot, L., Le Gouellec, A., Di Guilmi, A.M., Vernet, T., Dideberg, O., Dessen, A.
Deposit date:2004-10-08
Release date:2004-11-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae
J.Biol.Chem., 280, 2005
2BG1
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ACTIVE SITE RESTRUCTURING REGULATES LIGAND RECOGNITION IN CLASSA PENICILLIN-BINDING PROTEINS (PBPS)
Descriptor:PENICILLIN-BINDING PROTEIN 1B, SULFATE ION, CHLORIDE ION
Authors:Macheboeuf, P., Di Guilmi, A.M., Job, V., Vernet, T., Dideberg, O., Dessen, A.
Deposit date:2004-12-16
Release date:2005-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Active Site Restructuring Regulates Ligand Recognition in Class a Penicillin-Binding Proteins
Proc.Natl.Acad.Sci.USA, 102, 2005
2UWX
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ACTIVE SITE RESTRUCTURING REGULATES LIGAND RECOGNITION IN CLASS A PENICILLIN-BINDING PROTEINS
Descriptor:PENICILLIN-BINDING PROTEIN 1B, SULFATE ION, CHLORIDE ION, ...
Authors:Macheboeuf, P., DiGuilmi, A.M., Job, V., Vernet, T., Dideberg, O., Dessen, A.
Deposit date:2007-03-23
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Active Site Restructuring Regulates Ligand Recognition in Class a Penicillin-Binding Proteins
Proc.Natl.Acad.Sci.USA, 102, 2005
2V2F
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CRYSTAL STRUCTURE OF PBP1A FROM DRUG-RESISTANT STRAIN 5204 FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:PENICILLIN BINDING PROTEIN 1A, BARIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Job, V., Carapito, R., Vernet, T., Dideberg, O., Dessen, A., Zapun, A.
Deposit date:2007-06-05
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Common Alterations in Pbp1A from Resistant Streptococcus Pneumoniae Decrease its Reactivity Toward {Beta}-Lactams: Structural Insights.
J.Biol.Chem., 283, 2008
2XD1
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ACTIVE SITE RESTRUCTURING REGULATES LIGAND RECOGNITION IN CLASS A PENICILLIN-BINDING PROTEINS
Descriptor:PENICILLIN-BINDING PROTEIN 1B, CEFOTAXIME, C3' cleaved, ...
Authors:Macheboeuf, P., Di Guilmi, A.M., Job, V., Vernet, T., Dideberg, O., Dessen, A.
Deposit date:2010-04-28
Release date:2010-05-26
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Active Site Restructuring Regulates Ligand Recognition in Class a Penicillin-Binding Proteins.
Proc.Natl.Acad.Sci.USA, 102, 2005
2Y1V
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FULL LENGTH STRUCTURE OF RRGB PILUS PROTEIN FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:CELL WALL SURFACE ANCHOR FAMILY PROTEIN, NICKEL (II) ION
Authors:El-Mortaji, L., Contreras-Martel, C., Manzano, C., Vernet, T., Dessen, A., DiGuilmi, A.M.
Deposit date:2010-12-10
Release date:2011-11-09
Last modified:2012-01-25
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:The Full-Length Streptococcus Pneumoniae Major Pilin Rrgb Crystallizes in a Fibre-Like Structure, which Presents the D1 Isopeptide Bond and Provides Details on the Mechanism of Pilus Polymerization.
Biochem.J., 441, 2012
3GDB
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CRYSTAL STRUCTURE OF SPR0440 GLYCOSIDE HYDROLASE DOMAIN, ENDO-D FROM STREPTOCOCCUS PNEUMONIAE R6
Descriptor:Putative uncharacterized protein spr0440, ACETIC ACID, TRIETHYLENE GLYCOL
Authors:Jiang, Y.-L., Frolet, C., Di-guilmi, A.-M., Zhou, C.-Z., Vernet, T., Chen, Y.-X.
Deposit date:2009-02-24
Release date:2009-03-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structure of Spr0440 glycoside hydrolase domain, Endo-D from Streptococcus pneumoniae R6
To be published
3NZ3
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CRYSTAL STRUCTURE OF THE MUCIN-BINDING DOMAIN OF SPR1345 FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:Putative uncharacterized protein, TRIETHYLENE GLYCOL, SULFATE ION
Authors:Du, Y., He, Y.-X., Zhang, Z.-Y., Yang, Y.-H., Shi, W.-W., Frolet, C., Guilmi, A.M., Vernet, T., Zhou, C.-Z., Chen, Y.
Deposit date:2010-07-15
Release date:2011-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the mucin-binding domain of Spr1345 from Streptococcus pneumoniae
J.Struct.Biol., 174, 2011
1WRA
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CRYSTAL STRUCTURE OF PHOSPHORYLCHOLINE ESTERASE DOMAIN OF THE VIRULENCE FACTOR CHOLINE BINDING PROTEIN E FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:Teichoic acid phosphorylcholine esterase/choline binding protein E (cbpE), FE (III) ION, CALCIUM ION, ...
Authors:Garau, G., Dideberg, O.
Deposit date:2004-10-13
Release date:2005-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of phosphorylcholine esterase domain of the virulence factor choline-binding protein e from streptococcus pneumoniae: new structural features among the metallo-beta-lactamase superfamily
J.Biol.Chem., 280, 2005
3CX3
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CRYSTAL STRUCTURE ANALYSIS OF THE STREPTOCOCCUS PNEUMONIAE ADCAII PROTEIN
Descriptor:Lipoprotein, SODIUM ION, ZINC ION
Authors:Loisel, E., Durmort, C., Jacquamet, L.
Deposit date:2008-04-23
Release date:2008-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:AdcAII, a new pneumococcal Zn-binding protein homologous with ABC transporters: biochemical and structural analysis.
J.Mol.Biol., 381, 2008
3QFM
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CRYSTAL STRUCTURE OF STREPTOCOCCAL ASYMMETRIC AP4A HYDROLASE AND PHOSPHODIESTERASE SPR1479/SAPH
Descriptor:Putative uncharacterized protein, MANGANESE (II) ION, FE (III) ION
Authors:Jiang, Y.L., Zhang, J.W., Yu, W.L., Cheng, W., Zhang, C.C., Zhou, C.Z., Chen, Y.
Deposit date:2011-01-22
Release date:2011-08-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and enzymatic characterization of a Streptococcal ATP/diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH
To be Published
3QFN
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CRYSTAL STRUCTURE OF STREPTOCOCCAL ASYMMETRIC AP4A HYDROLASE AND PHOSPHODIESTERASE SPR1479/SAPH IN COMPLEX WITH INORGANIC PHOSPHATE
Descriptor:Putative uncharacterized protein, PHOSPHATE ION, MANGANESE (II) ION, ...
Authors:Jiang, Y.L., Zhang, J.W., Yu, W.L., Cheng, W., Zhang, C.C., Zhou, C.Z., Chen, Y.
Deposit date:2011-01-22
Release date:2011-08-24
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural and enzymatic characterization of a Streptococcal ATP/diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH
To be Published
3QFO
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CRYSTAL STRUCTURE OF STREPTOCOCCAL ASYMMETRIC AP4A HYDROLASE AND PHOSPHODIESTERASE SPR1479/SAPH IM COMPLEX WITH AMP
Descriptor:Putative uncharacterized protein, ADENOSINE MONOPHOSPHATE, FE (III) ION, ...
Authors:Jiang, Y.L., Zhang, J.W., Yu, W.L., Cheng, W., Zhang, C.C., Zhou, C.Z., Chen, Y.
Deposit date:2011-01-22
Release date:2011-08-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and enzymatic characterization of a Streptococcal ATP/diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH
To be Published
3RPM
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CRYSTAL STRUCTURE OF THE FIRST GH20 DOMAIN OF A NOVEL BETA-N-ACETYL-HEXOSAMINIDASE STRH FROM STREPTOCOCCUS PNEUMONIAE R6
Descriptor:Beta-N-acetyl-hexosaminidase, N-ACETYL-D-GLUCOSAMINE, PENTAETHYLENE GLYCOL
Authors:Jiang, Y.L., Yu, W.L., Zhang, J.W.
Deposit date:2011-04-27
Release date:2011-10-26
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the substrate specificity of a novel beta-N-acetylhexosaminidase StrH protein from Streptococcus pneumoniae R6
J.Biol.Chem., 286, 2011
4X36
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CRYSTAL STRUCTURE OF THE AUTOLYSIN LYTA FROM STREPTOCOCCUS PNEUMONIAE TIGR4
Descriptor:Autolysin, GLYCEROL, ZINC ION, ...
Authors:Cheng, W., Li, Q., Zhou, C.Z., Chen, Y.X.
Deposit date:2014-11-28
Release date:2015-05-27
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Full-length structure of the major autolysin LytA.
Acta Crystallogr.,Sect.D, 71, 2015
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