Author results

1EPO
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ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH CP-81,282 (MOR PHE NLE CHF NME)
分子名称:ENDOTHIAPEPSIN, N-(morpholin-4-ylcarbonyl)-L-phenylalanyl-N-[(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-(methylamino)-4-oxobutyl]-L-norleucinamide
著者Veerapandian, B., Cooper, J.B., Blundell, T.L.
登録日1994-07-27
公開日1994-12-20
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Direct observation by X-ray analysis of the tetrahedral intermediate of aspartic proteinases.
Protein Sci., 1, 1992
2ER7
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X-RAY ANALYSES OF ASPARTIC PROTEINASES.III. THREE-DIMENSIONAL STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH A TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN AT 1.6 ANGSTROMS RESOLUTION
分子名称:ENDOTHIAPEPSIN, TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN, SULFATE ION
著者Veerapandian, B., Cooper, J.B., Szelke, M., Blundell, T.L.
登録日1990-11-12
公開日1991-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献X-ray analyses of aspartic proteinases. III Three-dimensional structure of endothiapepsin complexed with a transition-state isostere inhibitor of renin at 1.6 A resolution.
J.Mol.Biol., 216, 1990
4I1B
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FUNCTIONAL IMPLICATIONS OF INTERLEUKIN-1BETA BASED ON THE THREE-DIMENSIONAL STRUCTURE
分子名称:INTERLEUKIN-1 BETA
著者Veerapandian, B., Poulos, T.L., Gilliland, G.L., Raag, R., Svensson, L.A., Masui, Y., Hirai, Y.
登録日1990-03-27
公開日1990-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Functional implications of interleukin-1 beta based on the three-dimensional structure.
Proteins, 12, 1992
3ER5
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THE ACTIVE SITE OF ASPARTIC PROTEINASES
分子名称:ENDOTHIAPEPSIN, H-189
著者Bailey, D., Veerapandian, B., Cooper, J., Szelke, M., Blundell, T.L.
登録日1991-01-05
公開日1991-04-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray-crystallographic studies of complexes of pepstatin A and a statine-containing human renin inhibitor with endothiapepsin.
Biochem.J., 289 ( Pt 2), 1993
1FNA
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CRYSTAL STRUCTURE OF THE TENTH TYPE III CELL ADHESION MODULE OF HUMAN FIBRONECTIN
分子名称:FIBRONECTIN CELL-ADHESION MODULE TYPE III-10
著者Dickinson, C.D., Veerapandian, B., Ely, K.R.
登録日1994-01-11
公開日1994-04-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the tenth type III cell adhesion module of human fibronectin.
J.Mol.Biol., 236, 1994
1OPG
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OPG2 FAB FRAGMENT
分子名称:OPG2 FAB (LIGHT CHAIN), OPG2 FAB (HEAVY CHAIN)
著者Kodandapani, R., Veerapandian, B., Ely, K.R.
登録日1995-04-28
公開日1995-07-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the OPG2 Fab. An antireceptor antibody that mimics an RGD cell adhesion site.
J.Biol.Chem., 270, 1995
5ER2
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HIGH-RESOLUTION X-RAY DIFFRACTION STUDY OF THE COMPLEX BETWEEN ENDOTHIAPEPSIN AND AN OLIGOPEPTIDE INHIBITOR. THE ANALYSIS OF THE INHIBITOR BINDING AND DESCRIPTION OF THE RIGID BODY SHIFT IN THE ENZYME
分子名称:ENDOTHIAPEPSIN, 6-ammonio-N-{[(2R,3R)-3-{[N-(tert-butoxycarbonyl)-L-phenylalanyl-3-(1H-imidazol-3-ium-4-yl)-L-alanyl]amino}-4-cyclohexyl-2-hydroxybutyl](2-methylpropyl)carbamoyl}-L-norleucyl-L-phenylalanine
著者Sali, A., Veerapandian, B., Cooper, J.B., Foundling, S.I., Hoover, D.J., Blundell, T.L.
登録日1991-01-02
公開日1991-04-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor: the analysis of the inhibitor binding and description of the rigid body shift in the enzyme.
EMBO J., 8, 1989
21BI
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INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 71 REPLACED BY ALA) (C71A)
分子名称:INTERLEUKIN-1 BETA
著者Veerapandian, B., Poulos, T.L., Gilliland, G.L., Masui, Y., Hirai, Y.
登録日1991-03-21
公開日1992-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献

31BI
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INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 71 REPLACED BY SER) (C71S)
分子名称:INTERLEUKIN-1 BETA PRECURSOR
著者Veerapandian, B., Poulos, T.L., Gilliland, G.L., Masui, Y., Hirai, Y.
登録日1991-03-21
公開日1992-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献

41BI
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INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 8 REPLACED BY ALA (C8A)
分子名称:INTERLEUKIN-1 BETA
著者Veerapandian, B., Poulos, T.L., Gilliland, G.L., Masui, Y., Hirai, Y.
登録日1992-02-03
公開日1992-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献

1BM3
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IMMUNOGLOBULIN OPG2 FAB-PEPTIDE COMPLEX
分子名称:IMMUNOGLOBULIN OPG2 FAB, CONSTANT DOMAIN, VARIABLE DOMAIN
著者Kodandapani, R., Veerapandian, L., Ni, C.Z., Chiou, C.-K., Whital, R., Kunicki, T.J., Ely, K.R.
登録日1999-04-15
公開日1999-04-20
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational change in an anti-integrin antibody: structure of OPG2 Fab bound to a beta 3 peptide.
Biochem.Biophys.Res.Commun., 251, 1998
1ENT
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X-RAY ANALYSES OF ASPARTIC PROTEINASES. THE THREE-DIMENSIONAL STRUCTURE AT 2.1 ANGSTROMS RESOLUTION OF ENDOTHIAPEPSIN
分子名称:ENDOTHIAPEPSIN, N-(tert-butoxycarbonyl)-L-phenylalanyl-N-{(1S)-1-[(R)-hydroxy(2-{[(2S)-2-methylbutyl]amino}-2-oxoethyl)phosphoryl]-3-methylbutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide, SULFATE ION
著者Blundell, T.L., Dealwis, C.G.
登録日1992-03-11
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray analyses of aspartic proteinases. The three-dimensional structure at 2.1 A resolution of endothiapepsin.
J.Mol.Biol., 211, 1990
1IOB
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INTERLEUKIN-1 BETA FROM JOINT X-RAY AND NMR REFINEMENT
分子名称:INTERLEUKIN-1 BETA
著者Shaanan, B., Clore, G.M.
登録日1996-03-14
公開日1996-08-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å), SOLUTION NMR
主引用文献Combining experimental information from crystal and solution studies: joint X-ray and NMR refinement.
Science, 257, 1992
1ER8
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THE ACTIVE SITE OF ASPARTIC PROTEINASES
分子名称:Endothiapepsin, H-77
著者Hemmings, A.M., Veerapandian, B., Szelke, M., Cooper, J.B., Blundell, T.L.
登録日1989-10-16
公開日1991-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Active Site of Aspartic Proteinases
FEBS Lett., 174, 1984
1LMA
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PROTEIN HYDRATION AND WATER STRUCTURE: X-RAY ANALYSIS OF A CLOSELY PACKED PROTEIN CRYSTAL WITH VERY LOW SOLVENT CONTENT
分子名称:HEN EGG WHITE LYSOZYME, NITRATE ION
著者Madhusudan, Kodandapani, R., Vijayan, M.
登録日1992-08-14
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Protein hydration and water structure: X-ray analysis of a closely packed protein crystal with very low solvent content.
Acta Crystallogr.,Sect.D, 49, 1993
1RHA
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WATER DEPENDENT DOMAIN MOTION AND FLEXIBILITY IN RIBONUCLEASE A AND THE INVARIANT FEATURES IN ITS HYDRATION SHELL. AN X-RAY STUDY OF TWO LOW HUMIDITY CRYSTAL FORMS OF THE ENZYME
分子名称:RIBONUCLEASE A
著者Radha Kishan, K.V., Chandra, N.R., Sudarsanakumar, C., Suguna, K., Vijayan, M.
登録日1994-11-13
公開日1995-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Water-dependent domain motion and flexibility in ribonuclease A and the invariant features in its hydration shell. An X-ray study of two low-humidity crystal forms of the enzyme.
Acta Crystallogr.,Sect.D, 51, 1995
1RHB
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WATER DEPENDENT DOMAIN MOTION AND FLEXIBILITY IN RIBONUCLEASE A AND THE INVARIANT FEATURES IN ITS HYDRATION SHELL. AN X-RAY STUDY OF TWO LOW HUMIDITY CRYSTAL FORMS OF THE ENZYME
分子名称:RIBONUCLEASE A
著者Radha Kishan, K.V., Chandra, N.R., Sudarsanakumar, C., Suguna, K., Vijayan, M.
登録日1994-11-13
公開日1995-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Water-dependent domain motion and flexibility in ribonuclease A and the invariant features in its hydration shell. An X-ray study of two low-humidity crystal forms of the enzyme.
Acta Crystallogr.,Sect.D, 51, 1995
3ER3
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THE ACTIVE SITE OF ASPARTIC PROTEINASES
分子名称:ENDOTHIAPEPSIN, 6-ammonio-N-[(2R,4R,5R)-5-{[N-(tert-butoxycarbonyl)-L-phenylalanyl-3-(1H-imidazol-3-ium-4-yl)-L-alanyl]amino}-6-cyclohexyl-4-hydroxy-2-(2-methylpropyl)hexanoyl]-L-norleucylphenylalanine
著者Al-Karadaghi, S., Cooper, J.B., Veerapandian, B., Hoover, D., Blundell, T.L.
登録日1991-01-02
公開日1991-04-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Active Site of Aspartic Proteinases
FEBS Lett., 174, 1984
4ER2
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THE ACTIVE SITE OF ASPARTIC PROTEINASES
分子名称:ENDOTHIAPEPSIN, PEPSTATIN, SULFATE ION
著者Bailey, D., Veerapandian, B., Cooper, J.B., Blundell, T.L.
登録日1990-10-20
公開日1991-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The active site of aspartic proteinases
FEBS Lett., 174, 1984
4LYM
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CRYSTAL STRUCTURE OF LOW HUMIDITY TETRAGONAL LYSOZYME AT 2.1-ANGSTROMS RESOLUTION. VARIABILITY IN HYDRATION SHELL AND ITS STRUCTURAL CONSEQUENCES
分子名称:HEN EGG WHITE LYSOZYME
著者Kodandapani, R., Suresh, C.G., Vijayan, M.
登録日1990-07-30
公開日1991-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of low humidity tetragonal lysozyme at 2.1-A resolution. Variability in hydration shell and its structural consequences.
J.Biol.Chem., 265, 1990
1EPL
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A STRUCTURAL COMPARISON OF 21 INHIBITOR COMPLEXES OF THE ASPARTIC PROTEINASE FROM ENDOTHIA PARASITICA
分子名称:ENDOTHIAPEPSIN, PS1, PRO-LEU-GLU-PSA-ARG-LEU
著者Al-Karadaghi, S., Cooper, J.B., Strop, P., Blundell, T.L.
登録日1994-07-27
公開日1994-12-20
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica.
Protein Sci., 3, 1994
1EPM
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A STRUCTURAL COMPARISON OF 21 INHIBITOR COMPLEXES OF THE ASPARTIC PROTEINASE FROM ENDOTHIA PARASITICA
分子名称:ENDOTHIAPEPSIN, PS2, THR-PHE-GLN-ALA-PSA-LEU-ARG-GLU, ...
著者Crawford, M., Cooper, J.B., Strop, P., Blundell, T.L.
登録日1994-07-27
公開日1994-12-20
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica.
Protein Sci., 3, 1994
1EPN
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A STRUCTURAL COMPARISON OF 21 INHIBITOR COMPLEXES OF THE ASPARTIC PROTEINASE FROM ENDOTHIA PARASITICA
分子名称:ENDOTHIAPEPSIN, N-(morpholin-4-ylcarbonyl)-L-phenylalanyl-N-[(1R,2S)-1-(cyclohexylmethyl)-2-hydroxy-3-(1-methylethoxy)-3-oxopropyl]-S-methyl-L-cysteinamide, SULFATE ION
著者Crawford, M., Cooper, J.B., Blundell, T.L.
登録日1994-07-27
公開日1994-12-20
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica.
Protein Sci., 3, 1994
1EPP
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ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH PD-130,693 (MAS PHE LYS+MTF STA MBA)
分子名称:ENDOTHIAPEPSIN, SULFATE ION, N-(dimethylsulfamoyl)-L-phenylalanyl-N-[(1S,2S)-2-hydroxy-4-{[(2S)-2-methylbutyl]amino}-1-(2-methylpropyl)-4-oxobutyl]-N~6~-(methylcarbamothioyl)-L-lysinamide
著者Wallace, B.A., Cooper, J.B., Blundell, T.L.
登録日1994-07-27
公開日1994-12-20
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors.
J.Med.Chem., 36, 1993
1EPQ
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ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH PD-133,450 (SOT PHE GLY+SCC GCL)
分子名称:ENDOTHIAPEPSIN, N-[(1R)-2-{[(1R,2R,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]amino}-1-(ethylsulfanyl)-2-oxoethyl]-Nalpha-(morpholin-4-ylsulfonyl)-D-phenylalaninamide, SULFATE ION
著者Dealwis, C., Cooper, J.B., Blundell, T.L.
登録日1994-07-27
公開日1994-12-20
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors.
J.Med.Chem., 36, 1993
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