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The crystal structure of monomer Q108K:K40L:Y60W CRBPII bound to all-trans-retinal
Descriptor:	ACETATE ION, RETINAL, Retinol-binding protein 2
Authors:	Nossoni, Z, Assar, Z, Wang, W, Vasileiou, C, Borhan, B, Geiger, J.H.
Deposit date:	2015-04-28
Release date:	2016-05-11
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates. Structure, 24, 2016

4QYP

The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinal
Descriptor:	ACETATE ION, RETINAL, Retinol-binding protein 2
Authors:	Nossoni, Z, Assar, Z, Yapici, I, Nosrati, M, Wang, W, Berbasova, T, Vasileiou, C, Borhan, B, Geiger, H.
Deposit date:	2014-07-25
Release date:	2014-12-10
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.62 Å)
Cite:	Structures of holo wild-type human cellular retinol-binding protein II (hCRBPII) bound to retinol and retinal. Acta Crystallogr.,Sect.D, 70, 2014

4QYN

The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinol
Descriptor:	ACETATE ION, RETINOL, Retinol-binding protein 2
Authors:	Nossoni, Z, Assar, Z, Yapici, I, Nosrati, M, Wang, W, Berbasova, T, Vasileiou, C, Borhan, B, Geiger, H.
Deposit date:	2014-07-24
Release date:	2014-12-31
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (1.19 Å)
Cite:	Structures of holo wild-type human cellular retinol-binding protein II (hCRBPII) bound to retinol and retinal. Acta Crystallogr.,Sect.D, 70, 2014

2G7B

Crystal Structure of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding Protein Type II In Complex With All-Trans-Retinal At 1.18 Angstroms Resolution
Descriptor:	ALL-TRANS AXEROPHTHENE, Cellular retinoic acid-binding protein 2, SODIUM ION
Authors:	Vaezeslami, S, Geiger, J.H.
Deposit date:	2006-02-27
Release date:	2007-04-17
Last modified:	2021-10-20
Method:	X-RAY DIFFRACTION (1.18 Å)
Cite:	Protein design: reengineering cellular retinoic acid binding protein II into a rhodopsin protein mimic. J.Am.Chem.Soc., 129, 2007

2G78

Crystal Structure of the R132K:Y134F Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinoic Acid at 1.70 Angstroms Resolution
Descriptor:	Cellular retinoic acid-binding protein 2, RETINOIC ACID, SODIUM ION
Authors:	Vaezeslami, S, Geiger, J.H.
Deposit date:	2006-02-27
Release date:	2007-04-17
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Protein design: reengineering cellular retinoic acid binding protein II into a rhodopsin protein mimic. J.Am.Chem.Soc., 129, 2007

2G79

Crystal Structure of the R132K:Y134F Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinal at 1.69 Angstroms Resolution
Descriptor:	Cellular retinoic acid-binding protein 2, RETINAL, SODIUM ION, ...
Authors:	Vaezeslami, S, Geiger, J.H.
Deposit date:	2006-02-27
Release date:	2007-04-17
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.69 Å)
Cite:	Protein design: reengineering cellular retinoic acid binding protein II into a rhodopsin protein mimic. J.Am.Chem.Soc., 129, 2007

3I17

Crystal structure of the apo R132K:L121E mutant of cellular retinoic acid-binding protein II at 1.68 angstrom resolution
Descriptor:	Cellular retinoic acid-binding protein 2
Authors:	Jia, X, Watson, C.T, Geiger, J.H.
Deposit date:	2009-06-25
Release date:	2009-07-28
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.68 Å)
Cite:	Elucidating the exact role of engineered CRABPII residues for the formation of a retinal protonated Schiff base. Proteins, 77, 2009

5U6G

Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal
Descriptor:	RETINAL, Retinol-binding protein 2
Authors:	Assar, Z, Geiger, J.H.
Deposit date:	2016-12-08
Release date:	2017-10-18
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal To Be Published

6ON5

Crystal Structure of the Zn-bound Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57H Mutant of Human Cellular Retinol Binding Protein II
Descriptor:	Retinol-binding protein 2, ZINC ION
Authors:	Ghanbarpour, A, Geiger, J.
Deposit date:	2019-04-20
Release date:	2019-10-16
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.638 Å)
Cite:	Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches. J.Am.Chem.Soc., 141, 2019

6ON8

Crystal Structure of the Reduced Form of Apo Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57H Mutant of Human Cellular Retinol Binding Protein II
Descriptor:	Retinol-binding protein 2
Authors:	Ghanbarpour, A, Geiger, J.
Deposit date:	2019-04-20
Release date:	2019-10-16
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.395 Å)
Cite:	Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches. J.Am.Chem.Soc., 141, 2019

6ON7

Crystal Structure of Apo Domain-Swapped Dimer Q108K:T51D:A28C:L36C Mutant of Human Cellular Retinol Binding Protein II
Descriptor:	Retinol-binding protein 2
Authors:	Ghanbarpour, A, Geiger, J.
Deposit date:	2019-04-20
Release date:	2019-10-16
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.981 Å)
Cite:	Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches. J.Am.Chem.Soc., 141, 2019

6C7Z

Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with synthetic Ligand Julolidine
Descriptor:	(2E,4E)-3-methyl-5-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)penta-2,4-dienal, ACETATE ION, Retinol-binding protein 2
Authors:	Nosrati, M, Geiger, J.H.
Deposit date:	2018-01-23
Release date:	2018-04-25
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.42 Å)
Cite:	A Genetically Encoded Ratiometric pH Probe: Wavelength Regulation-Inspired Design of pH Indicators. Chembiochem, 19, 2018

3CR6

Crystal Structure of the R132K:R111L:A32E Mutant of Cellular Retinoic Acid Binding Protein Type II Complexed with C15-aldehyde (a retinal analog) at 1.22 Angstrom resolution.
Descriptor:	1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene, Cellular retinoic acid-binding protein 2
Authors:	Jia, X, Geiger, J.H.
Deposit date:	2008-04-04
Release date:	2009-03-17
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.22 Å)
Cite:	Two distinctive orientations of binding determined by a single mutation in the CRABPII mutant-C15-aldehyde complexes To be Published

4ZH6

Crystal Structure of the Domain-Swapped Dimer Y60L mutant of Human Cellular Retinol Binding Protein II
Descriptor:	ACETATE ION, Retinol-binding protein 2
Authors:	Assar, Z, Nossoni, Z, Geiger, J.H.
Deposit date:	2015-04-24
Release date:	2016-06-08
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.5497 Å)
Cite:	Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates. Structure, 24, 2016

4ZH9

Crystal Structure of the Domain-Swapped Dimer Wild-Type of Human Cellular Retinol Binding Protein II
Descriptor:	Retinol-binding protein 2
Authors:	Assar, Z, Nossoni, Z, Geiger, J.H.
Deposit date:	2015-04-24
Release date:	2016-06-08
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.66 Å)
Cite:	Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates. Structure, 24, 2016

4ZR2

Crystal Structure of the Domain-Swapped Dimer K40L:Q108K:Y60W mutant of Human Cellular Retinol Binding Protein II
Descriptor:	ACETATE ION, RETINAL, Retinol-binding protein 2
Authors:	Assar, Z, Nossoni, Z, Geiger, J.H.
Deposit date:	2015-05-11
Release date:	2016-06-08
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.8024 Å)
Cite:	Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates. Structure, 24, 2016

5DG4

Crystal structure of monomer human cellular retinol binding protein II-Y60L
Descriptor:	ACETATE ION, Retinol-binding protein 2
Authors:	Assar, Z, Nossoni, Z, Wang, W, Gieger, J.H, Borhan, B.
Deposit date:	2015-08-27
Release date:	2016-09-21
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates. Structure, 24, 2016

8W00

Q108K:K40L:T51V:T53S:Y19W:R58W:L117E mutant of hCRBPII bound to synthetic fluorophore TD-1V
Descriptor:	(2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2
Authors:	Nossoni, Z, Bingham, C.R, Geiger, J.H.
Deposit date:	2024-02-13
Release date:	2024-04-03
Method:	X-RAY DIFFRACTION (1.23 Å)
Cite:	Regulation of Emission via a Protein-Bound Fluorophore To Be Published

8VZZ

Q108K:K40L:T51V:T53S:Y19W:R58W mutant of hCRBPII bound to synthetic fluorophore TD-1V
Descriptor:	(2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2
Authors:	Nosssoni, Z, Bingham, C.R, Geiger, J.H, Borhan, B.
Deposit date:	2024-02-13
Release date:	2024-04-03
Method:	X-RAY DIFFRACTION (1.22 Å)
Cite:	Regulation of Emission via a Protein-Bound Fluorophore To Be Published

8VZX

Q108K:K40L:T53A:R58F mutant of hCRBPII bound to synthetic fluorophore TD-1V
Descriptor:	(2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2
Authors:	Nossoni, Z, Bingham, C.R, Geiger, J.H.
Deposit date:	2024-02-13
Release date:	2024-04-03
Method:	X-RAY DIFFRACTION (1.47 Å)
Cite:	Regulation of Emission via a Protein-Bound Fluorophore To Be Published

8VZY

Q108K:K40L:T51V:T53S:R58Y mutant of hCRBPII bound to synthetic fluorophore TD-1V
Descriptor:	(2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2
Authors:	Nossoni, Z, Bingham, C.R, Geiger, J.H, Borhan, B.
Deposit date:	2024-02-13
Release date:	2024-04-03
Method:	X-RAY DIFFRACTION (1.34 Å)
Cite:	Regulation of Emission via a Protein-Bound Fluorophore To Be Published

8W02

Q108K:K40L:T51V:T53S:R58W mutant of hCRBPII bound to synthetic fluorophore TD-1V
Descriptor:	(2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2
Authors:	Ghanbarpour, A, Geiger, J.H, Borhan, B.
Deposit date:	2024-02-13
Release date:	2024-04-03
Method:	X-RAY DIFFRACTION (1.499 Å)
Cite:	Regulation of Emission via a Protein-Bound Fluorophore To Be Published

6VIT

The Crystal Structure of Apo Domain-Swapped dimer Q108K:T51D:I32C Variant of HCRBPII with an Engineered Disulfide Bond
Descriptor:	Retinol-binding protein 2
Authors:	Ghanbarpour, A, Geiger, J.
Deposit date:	2020-01-13
Release date:	2020-08-19
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (3.2 Å)
Cite:	Human Cellular Retinol Binding Protein II Forms a Domain-Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering. Chembiochem, 21, 2020

6VIS

The Crystal Structure of Domain-Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F:V62E Variant of HCRBPII
Descriptor:	GLYCEROL, Retinol-binding protein 2
Authors:	Ghanbarpour, A, Geiger, J.
Deposit date:	2020-01-13
Release date:	2020-09-09
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.79 Å)
Cite:	Human Cellular Retinol Binding Protein II Forms a Domain-Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering. Chembiochem, 21, 2020

6WNF

The Crystal Structure of Apo Domain-Swapped Dimer Q108K:K40D:T53A:R58L:Q38F:Q4F:F57H Variant of HCRBPII
Descriptor:	ACETATE ION, GLYCEROL, Retinol-binding protein 2
Authors:	Ghanbarpour, A, Geiger, J.
Deposit date:	2020-04-22
Release date:	2020-08-19
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.67 Å)
Cite:	Human Cellular Retinol Binding Protein II Forms a Domain-Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering. Chembiochem, 21, 2020

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