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2LOS
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BACKBONE STRUCTURE OF HUMAN MEMBRANE PROTEIN TMEM14C
Descriptor:Transmembrane protein 14C
Authors:Klammt, C., Vajpai, N., Maslennikov, I., Riek, R., Choe, S.
Deposit date:2012-01-26
Release date:2012-05-23
Last modified:2012-08-15
Method:SOLUTION NMR
Cite:Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
5A46
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FGFR1 IN COMPLEX WITH DOVITINIB
Descriptor:FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B, ...
Authors:Klein, T., Vajpai, N., Phillips, J.J., Davies, G., Holdgate, G.A., Phillips, C., Tucker, J.A., Norman, R.A., Scott, A.S., Higazi, D.R., Lowe, D., Thompson, G.S., Breeze, A.L.
Deposit date:2015-06-05
Release date:2015-08-05
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase.
Nat.Commun., 6, 2015
5A4C
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FGFR1 LIGAND COMPLEX
Descriptor:FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B, ...
Authors:Klein, T., Vajpai, N., Phillips, J.J., Davies, G., Holdgate, G.A., Phillips, C., Tucker, J.A., Norman, R.A., Scott, A.S., Higazi, D.R., Lowe, D., Thompson, G.S., Breeze, A.L.
Deposit date:2015-06-05
Release date:2015-08-05
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase.
Nat.Commun., 6, 2015
2LOM
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BACKBONE STRUCTURE OF HUMAN MEMBRANE PROTEIN HIGD1A
Descriptor:HIG1 domain family member 1A
Authors:Blain, K., Klammt, C., Maslennikov, I., Kwiatkowski, W., Choe, S.
Deposit date:2012-01-26
Release date:2012-05-23
Last modified:2012-08-15
Method:SOLUTION NMR
Cite:Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
2LON
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BACKBONE STRUCTURE OF HUMAN MEMBRANE PROTEIN HIGD1B
Descriptor:HIG1 domain family member 1B
Authors:Klammt, C., Maslennikov, I., Kwiatkowski, W., Choe, S.
Deposit date:2012-01-26
Release date:2012-05-23
Last modified:2012-08-15
Method:SOLUTION NMR
Cite:Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
2LOO
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BACKBONE STRUCTURE OF HUMAN MEMBRANE PROTEIN TMEM14A FROM NOE DATA
Descriptor:Transmembrane protein 14A
Authors:Eichmann, C., Klammt, C., Maslennikov, I., Riek, R., Choe, S.
Deposit date:2012-01-26
Release date:2012-05-23
Last modified:2012-08-15
Method:SOLUTION NMR
Cite:Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
2LOP
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BACKBONE STRUCTURE OF HUMAN MEMBRANE PROTEIN TMEM14A
Descriptor:Transmembrane protein 14A
Authors:Eichmann, C., Klammt, C., Maslennikov, I., Kwiatkowski, W., Riek, R., Choe, S.
Deposit date:2012-01-26
Release date:2012-05-23
Last modified:2012-08-15
Method:SOLUTION NMR
Cite:Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
2LOQ
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BACKBONE STRUCTURE OF HUMAN MEMBRANE PROTEIN FAM14B (INTERFERON ALPHA-INDUCIBLE PROTEIN 27-LIKE PROTEIN 1)
Descriptor:Interferon alpha-inducible protein 27-like protein 1
Authors:Klammt, C., Chui, E.J., Maslennikov, I., Kwiatkowski, W., Choe, S.
Deposit date:2012-01-26
Release date:2012-05-23
Last modified:2012-08-15
Method:SOLUTION NMR
Cite:Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
2LOR
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BACKBONE STRUCTURE OF HUMAN MEMBRANE PROTEIN TMEM141
Descriptor:Transmembrane protein 141
Authors:Bayrhuber, M., Klammt, C., Maslennikov, I., Riek, R., Choe, S.
Deposit date:2012-01-26
Release date:2012-05-23
Last modified:2012-08-15
Method:SOLUTION NMR
Cite:Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
3K5V
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STRUCTURE OF ABL KINASE IN COMPLEX WITH IMATINIB AND GNF-2
Descriptor:Tyrosine-protein kinase ABL1, 3-(6-{[4-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)benzamide, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, ...
Authors:Cowan-Jacob, S.W., Fendrich, G., Rummel, G., Strauss, A.
Deposit date:2009-10-08
Release date:2010-01-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.
Nature, 463, 2010
3CS9
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HUMAN ABL KINASE IN COMPLEX WITH NILOTINIB
Descriptor:Proto-oncogene tyrosine-protein kinase ABL1, Nilotinib
Authors:Cowan-Jacob, S.W., Fendrich, G., Manley, P., Liebetanz, J., Fabbro, D.
Deposit date:2008-04-09
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
Cancer Cell, 7, 2005