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3LTM
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BU of 3ltm by Molmil
Structure of a new family of artificial alpha helicoidal repeat proteins (alpha-Rep) based on thermostable HEAT-like repeats
Descriptor: Alpha-Rep4, DODECAETHYLENE GLYCOL, GLYCEROL, ...
Authors:Urvoas, A, Guellouz, A, Graille, M, van Tilbeurgh, H, Desmadril, M, Minard, P.
Deposit date:2010-02-16
Release date:2010-10-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Design, production and molecular structure of a new family of artificial alpha-helicoidal repeat proteins ( alpha Rep) based on thermostable HEAT-like repeats
J.Mol.Biol., 404, 2010
3LTJ
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BU of 3ltj by Molmil
Structure of a new family of artificial alpha helicoidal repeat proteins (alpha-Rep) based on thermostable HEAT-like repeats
Descriptor: AlphaRep-4
Authors:Urvoas, A, Guellouz, A, Graille, M, van Tilbeurgh, H, Desmadril, M, Minard, P.
Deposit date:2010-02-16
Release date:2010-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design, production and molecular structure of a new family of artificial alpha-helicoidal repeat proteins ( alpha Rep) based on thermostable HEAT-like repeats
J.Mol.Biol., 404, 2010
4XL5
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BU of 4xl5 by Molmil
X-ray structure of bGFP-A / EGFP complex
Descriptor: Green fluorescent protein, bGFP-A
Authors:Chevrel, A, Urvoas, A, Li de la Sierra-Gallay, I, Van Tilbeurgh, H, Minard, P, Valerio-Lepiniec, M.
Deposit date:2015-01-13
Release date:2015-08-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specific GFP-binding artificial proteins ( alpha Rep): a new tool for in vitro to live cell applications.
Biosci.Rep., 35, 2015
4XVP
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BU of 4xvp by Molmil
X-ray structure of bGFP-C / EGFP complex
Descriptor: BGFP-C, Green fluorescent protein
Authors:Chevrel, A, Urvoas, A, Li de la Sierra-Gallay, I, Van Tilbeurgh, H, Minard, P, Valerio-Lepiniec, M.
Deposit date:2015-01-27
Release date:2015-08-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Specific GFP-binding artificial proteins ( alpha Rep): a new tool for in vitro to live cell applications.
Biosci.Rep., 35, 2015
4JW3
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BU of 4jw3 by Molmil
Selection of specific protein binders for pre-defined targets from an optimized library of artificial helicoidal repeat proteins (alphaRep)
Descriptor: Alpha-helical artificial proteins, Neocarzinostatin
Authors:Guellouz, A, Valerio-Lepiniec, M, Urvoas, A, Chevrel, A, Graille, M, Fourati-Kammoun, Z, Desmadril, M, van Tilbeurgh, H, Minard, P.
Deposit date:2013-03-27
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep).
Plos One, 8, 2013
4JW2
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BU of 4jw2 by Molmil
Selection of specific protein binders for pre-defined targets from an optimized library of artificial helicoidal repeat proteins (alphaRep)
Descriptor: 1,2-ETHANEDIOL, A3 artificial protein, bA3-2: binder of A3 protein
Authors:Guellouz, A, Valerio-Lepiniec, M, Urvoas, A, Chevrel, A, Graille, M, Fourati-Kammoun, Z, Desmadril, M, van Tilbeurgh, H, Minard, P.
Deposit date:2013-03-27
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep).
Plos One, 8, 2013
4ZV6
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BU of 4zv6 by Molmil
Crystal structure of the artificial alpharep-7 octarellinV.1 complex
Descriptor: AlphaRep-7, Octarellin V.1
Authors:Figueroa, M, Sleutel, M, Urvoas, A, Valerio-Lepiniec, M, Minard, P, Martial, J.A, van de Weerdt, C.
Deposit date:2015-05-18
Release date:2016-05-25
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
J.Struct.Biol., 195, 2016
3UYP
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BU of 3uyp by Molmil
Crystal structure of the dengue virus serotype 4 envelope protein domain III in complex with the variable domains of Mab 4E11
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Envelope protein, GLYCEROL, ...
Authors:Cockburn, J.J.B, Navarro Sanchez, M.E, Fretes, N, Urvoas, A, Staropoli, I, Kikuti, C.M, Coffey, L.L, Arenzana Seisdedos, F, Bedouelle, H, Rey, F.A.
Deposit date:2011-12-06
Release date:2012-02-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody.
Structure, 20, 2012
3UZE
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BU of 3uze by Molmil
Crystal structure of the dengue virus serotype 3 envelope protein domain III in complex with the variable domains of Mab 4E11
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Envelope protein, ...
Authors:Cockburn, J.J.B, Navarro Sanchez, M.E, Fretes, N, Urvoas, A, Staropoli, I, Kikuti, C.M, Coffey, L.L, Arenzana Seisdedos, F, Bedouelle, H, Rey, F.A.
Deposit date:2011-12-07
Release date:2012-02-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody.
Structure, 20, 2012
3UZV
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BU of 3uzv by Molmil
Crystal structure of the dengue virus serotype 2 envelope protein domain III in complex with the variable domains of Mab 4E11
Descriptor: ETHANOL, anti-dengue Mab 4E11, envelope protein
Authors:Cockburn, J.J.B, Navarro Sanchez, M.E, Fretes, N, Urvoas, A, Staropoli, I, Kikuti, C.M, Coffey, L.L, Arenzana Seisdedos, F, Bedouelle, H, Rey, F.A.
Deposit date:2011-12-07
Release date:2012-02-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody.
Structure, 20, 2012
3UZQ
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BU of 3uzq by Molmil
Crystal structure of the dengue virus serotype 1 envelope protein domain III in complex with the variable domains of Mab 4E11
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ...
Authors:Cockburn, J.J.B, Navarro Sanchez, M.E, Fretes, N, Urvoas, A, Staropoli, I, Kikuti, C.M, Coffey, L.L, Arenzana Seisdedos, F, Bedouelle, H, Rey, F.A.
Deposit date:2011-12-07
Release date:2012-02-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody.
Structure, 20, 2012
8AW4
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BU of 8aw4 by Molmil
Structure of a complex of biosynthetic proteins bB-E3 and bGFPD-YY
Descriptor: ALPHAREP bB-E3, ALPHAREP bGFPD-YY
Authors:Li de la Sierra-Gallay, I.
Deposit date:2022-08-29
Release date:2022-12-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Hot spot induction allows selection of protein binders targeted to a predefined region of a bait protein
To Be Published
6FT5
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BU of 6ft5 by Molmil
Structure of A3_A3, an artificial bi-domain protein based on two identical alphaRep A3 domains
Descriptor: GLYCEROL, SULFATE ION, alphaRep A3_A3
Authors:Li de la Sierra-Gallay, I, Leger, C, Di Meo, T.
Deposit date:2018-02-20
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Ligand-induced conformational switch in an artificial bidomain protein scaffold.
Sci Rep, 9, 2019
5BOP
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BU of 5bop by Molmil
Crystal structure of the artificial nanobody octarellinV.1 complex
Descriptor: Nanobody, Octarellin V.1
Authors:Figueroa, M, Sleutel, M, Pardon, E, Steyaert, J, Martial, J.A, van de Weerdt, C.
Deposit date:2015-05-27
Release date:2016-05-25
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
J.Struct.Biol., 195, 2016
5DCQ
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BU of 5dcq by Molmil
Crystal structure of bacterial adhesin, FNE from Streptococcus equi spp. equi.
Descriptor: FORMIC ACID, Fibronectin-binding protein, artificial repeat proteins (alphaREP3)
Authors:Tiouajni, M, Graille, M, van Tilbeurgh, H.
Deposit date:2015-08-24
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural and functional analysis of the fibronectin-binding protein FNE from Streptococcus equi spp. equi.
FEBS J., 281, 2014
7Z0F
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BU of 7z0f by Molmil
CPAP:S-TUBULIN:IIH5 ALPHAREP COMPLEX
Descriptor: Centromere protein J, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Gigant, B, Campanacci, V.
Deposit date:2022-02-22
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.396 Å)
Cite:Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.
Proc.Natl.Acad.Sci.USA, 119, 2022
7Z0G
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BU of 7z0g by Molmil
CPAP:TUBULIN:IE5 ALPHAREP COMPLEX P1 SPACE GROUP
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Centromere protein J, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Gigant, B, Campanacci, V.
Deposit date:2022-02-22
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.487 Å)
Cite:Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.
Proc.Natl.Acad.Sci.USA, 119, 2022
7Q1E
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BU of 7q1e by Molmil
CPAP:TUBULIN:IIH5 ALPHAREP COMPLEX
Descriptor: Centromere protein J, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Campanacci, V, Gigant, b.
Deposit date:2021-10-19
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.
Proc.Natl.Acad.Sci.USA, 119, 2022
7Q1F
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BU of 7q1f by Molmil
CPAP:TUBULIN:IE5 ALPHAREP COMPLEX
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CITRATE ANION, Centromere protein J, ...
Authors:Campanacci, V, Gigant, b.
Deposit date:2021-10-19
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.
Proc.Natl.Acad.Sci.USA, 119, 2022
6GX7
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BU of 6gx7 by Molmil
Tubulin-CopN-alphaRep complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Gigant, B, Campanacci, V.
Deposit date:2018-06-26
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Insight into microtubule nucleation from tubulin-capping proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
6GVN
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BU of 6gvn by Molmil
Tubulin:TM-3 DARPin complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Gigant, B, Cantos Fernandes, S, Campanacci, V.
Deposit date:2018-06-21
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Insight into microtubule nucleation from tubulin-capping proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
6GVM
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BU of 6gvm by Molmil
Tubulin:F3II DARPin complex
Descriptor: F3II DARPIN, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Gigant, B, Campanacci, V, Cantos Fernandes, S.
Deposit date:2018-06-21
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Insight into microtubule nucleation from tubulin-capping proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
6G4J
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BU of 6g4j by Molmil
Structure of the protein kinase YabT from Bacillus subtilis in complex with an alphaREP crystallization helper
Descriptor: Probable serine/threonine-protein kinase YabT, alphaREP bE8
Authors:Nessler, S, Cavagnino, A, Rabefiraisana, J.L.
Deposit date:2018-03-27
Release date:2019-01-30
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:Structural Analysis of the Hanks-Type Protein Kinase YabT FromBacillus subtilisProvides New Insights in its DNA-Dependent Activation.
Front Microbiol, 9, 2018
6FSQ
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BU of 6fsq by Molmil
Structure of A3_bGFPD, an artificial bi-domain protein based on two different alphaRep domains : A3 and a GFP binding domain (bGFPD)
Descriptor: MALONATE ION, SODIUM ION, alphaRep A3_bGFPD
Authors:Li de la Sierra-Gallay, I, Leger, C.
Deposit date:2018-02-20
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Ligand-induced conformational switch in an artificial bidomain protein scaffold.
Sci Rep, 9, 2019
6GWC
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BU of 6gwc by Molmil
Tubulin:iE5 alphaRep complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALPHA-TUBULIN, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Gigant, B, Campanacci, V.
Deposit date:2018-06-22
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Selection and Characterization of Artificial Proteins Targeting the Tubulin alpha Subunit.
Structure, 27, 2019

 

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