Author results

1TCA
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THE SEQUENCE, CRYSTAL STRUCTURE DETERMINATION AND REFINEMENT OF TWO CRYSTAL FORMS OF LIPASE B FROM CANDIDA ANTARCTICA
Descriptor:LIPASE, N-ACETYL-D-GLUCOSAMINE
Authors:Uppenberg, J., Jones, T.A.
Deposit date:1994-02-28
Release date:1994-05-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The sequence, crystal structure determination and refinement of two crystal forms of lipase B from Candida antarctica.
Structure, 2, 1994
1TCB
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THE SEQUENCE, CRYSTAL STRUCTURE DETERMINATION AND REFINEMENT OF TWO CRYSTAL FORMS OF LIPASE B FROM CANDIDA ANTARCTICA
Descriptor:LIPASE, N-ACETYL-D-GLUCOSAMINE, B-OCTYLGLUCOSIDE
Authors:Uppenberg, J., Jones, T.A.
Deposit date:1994-02-28
Release date:1994-05-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The sequence, crystal structure determination and refinement of two crystal forms of lipase B from Candida antarctica.
Structure, 2, 1994
1TCC
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THE SEQUENCE, CRYSTAL STRUCTURE DETERMINATION AND REFINEMENT OF TWO CRYSTAL FORMS OF LIPASE B FROM CANDIDA ANTARCTICA
Descriptor:LIPASE, N-ACETYL-D-GLUCOSAMINE, B-OCTYLGLUCOSIDE
Authors:Uppenberg, J., Jones, T.A.
Deposit date:1994-02-28
Release date:1994-05-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The sequence, crystal structure determination and refinement of two crystal forms of lipase B from Candida antarctica.
Structure, 2, 1994
1LBS
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LIPASE (E.C.3.1.1.3) (TRIACYLGLYCEROL HYDROLASE)
Descriptor:LIPASE B, N-ACETYL-D-GLUCOSAMINE, N-HEXYLPHOSPHONATE ETHYL ESTER
Authors:Uppenberg, J., Jones, T.A.
Deposit date:1995-07-11
Release date:1995-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic and molecular-modeling studies of lipase B from Candida antarctica reveal a stereospecificity pocket for secondary alcohols.
Biochemistry, 34, 1995
1LBT
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LIPASE (E.C.3.1.1.3) (TRIACYLGLYCEROL HYDROLASE)
Descriptor:LIPASE B, N-ACETYL-D-GLUCOSAMINE, METHYLPENTA(OXYETHYL) HEPTADECANOATE
Authors:Uppenberg, J., Jones, T.A.
Deposit date:1995-07-11
Release date:1995-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic and molecular-modeling studies of lipase B from Candida antarctica reveal a stereospecificity pocket for secondary alcohols.
Biochemistry, 34, 1995
3PRG
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LIGAND BINDING DOMAIN OF HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR
Descriptor:PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA
Authors:Uppenberg, J., Svensson, C., Jaki, M., Bertilsson, G., Jendeberg, L., Berkenstam, A.
Deposit date:1998-08-24
Release date:1999-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the ligand binding domain of the human nuclear receptor PPARgamma.
J.Biol.Chem., 273, 1998
1QFC
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STRUCTURE OF RAT PURPLE ACID PHOSPHATASE
Descriptor:PROTEIN (PURPLE ACID PHOSPHATASE), N-ACETYL-D-GLUCOSAMINE, FE (III) ION, ...
Authors:Uppenberg, J., Lindqvist, F., Svensson, C., Ek-Rylander, B., Andersson, G.
Deposit date:1999-04-08
Release date:2000-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a mammalian purple acid phosphatase.
J.Mol.Biol., 290, 1999
1H54
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MALTOSE PHOSPHORYLASE FROM LACTOBACILLUS BREVIS
Descriptor:MALTOSE PHOSPHORYLASE, POTASSIUM ION, PHOSPHATE ION
Authors:Van Tilbeurgh, H., Egloff, M.-P.
Deposit date:2001-05-18
Release date:2001-09-05
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Maltose Phosphorylase from Lactobacillus Brevis: Unexpected Evolutionary Relationship with Glucoamylases.
Structure, 9, 2001
1TOU
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CRYSTAL STRUCTURE OF HUMAN ADIPOCYTE FATTY ACID BINDING PROTEIN IN COMPLEX WITH A NON-COVALENT LIGAND
Descriptor:Fatty acid-binding protein, adipocyte, 2-[(2-OXO-2-PIPERIDIN-1-YLETHYL)SULFANYL]-6-(TRIFLUOROMETHYL)PYRIMIDIN-4-OL
Authors:Ringom, R., Axen, E., Uppenberg, J., Lundback, T., Rondahl, L., Barf, T.
Deposit date:2004-06-15
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substituted benzylamino-6-(trifluoromethyl)pyrimidin-4(1H)-ones: a novel class of selective human A-FABP inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
1TOW
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CRYSTAL STRUCTURE OF HUMAN ADIPOCYTE FATTY ACID BINDING PROTEIN IN COMPLEX WITH A CARBOXYLIC ACID LIGAND
Descriptor:Fatty acid-binding protein, adipocyte, 4-(9H-CARBAZOL-9-YL)BUTANOIC ACID
Authors:Lehmann, F., Haile, S., Axen, E., Medina, C., Uppenberg, J., Svensson, S., Lundback, T., Rondahl, L., Barf, T.
Deposit date:2004-06-15
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target.
Bioorg.Med.Chem.Lett., 14, 2004
1WM0
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PPARGAMMA IN COMPLEX WITH A 2-BABA COMPOUND
Descriptor:Peroxisome proliferator activated receptor gamma, 14-mer from Nuclear receptor coactivator 2, 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID
Authors:Ostberg, T., Svensson, S., Selen, G., Uppenberg, J., Thor, M., Sundbom, M., Sydow-Backman, M., Gustavsson, A.L., Jendeberg, L.
Deposit date:2004-07-01
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A new class of peroxisome proliferator-activated receptor agonists with a novel binding epitope shows antidiabetic effects
J.Biol.Chem., 279, 2004
2G9N
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STRUCTURE OF THE DEAD DOMAIN OF HUMAN EUKARYOTIC INITIATION FACTOR 4A, EIF4A
Descriptor:Eukaryotic initiation factor 4A-I
Authors:Hogbom, M., Ogg, D., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Uppenberg, J., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)
Deposit date:2006-03-07
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
2GK9
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HUMAN PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE, TYPE II, GAMMA
Descriptor:phosphatidylinositol-4-phosphate 5-kinase, type II, gamma
Authors:Uppenberg, J., Hogbom, M., Ogg, D., Arrowsmith, C., Berglund, H., Collins, R., Ehn, M., Flodin, S., Flores, A., Graslund, S., Holmberg-Schiavone, L., Edwards, A., Hammarstrom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Hallberg, B.M., Structural Genomics Consortium (SGC)
Deposit date:2006-03-31
Release date:2006-05-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma
To be Published
2GSE
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CRYSTAL STRUCTURE OF HUMAN DIHYDROPYRIMIDINEASE-LIKE 2
Descriptor:Dihydropyrimidinase-related protein 2, CALCIUM ION
Authors:Ogg, D., Stenmark, P., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Kotenyova, T., Kursula, P., Nilsson-Ehle, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Holmberg-Schiavone, L., Thorsell, A.G., Uppenberg, J., Van Den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2006-04-26
Release date:2006-05-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of human collapsin response mediator protein 2, a regulator of axonal growth.
J.Neurochem., 101, 2007
2CN1
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE III (NT5C3)(CASP TARGET)
Descriptor:CYTOSOLIC 5'-NUCLEOTIDASE III
Authors:Wallden, K., Stenmark, P., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Kotenyova, T., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Uppenberg, J., Van Den Berg, S., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2006-05-17
Release date:2006-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Crystal Structure of Human Cytosolic 5'-Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition.
J.Biol.Chem., 282, 2007
2H4U
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CRYSTAL STRUCTURE OF HUMAN THIOESTERASE SUPERFAMILY MEMBER 2 (CASP TARGET)
Descriptor:Thioesterase superfamily member 2
Authors:Ogg, D.J., Uppenberg, J., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Grasslund, S., Flodin, S., Hammerstrom, M., Hogbom, M., Holmberg-Schiavone, L., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.-G., Weigelt, J., Hallberg, M., Structural Genomics Consortium (SGC)
Deposit date:2006-05-25
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of human thioesterase superfamily member 2
To be Published
2HE7
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FERM DOMAIN OF EPB41L3 (DAL-1)
Descriptor:Band 4.1-like protein 3
Authors:Hallberg, B.M., Busam, R.D., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Schiavone, L.H., Johansson, I., Hogbom, M., Karlberg, T., Kotenyova, T., Nilvebrandt, J., Norberg, P., Stenmark, P., Nordlund, P., Nilsson-ehle, P., Nyman, T., Ogg, D., Sagemark, J., Sundstrom, M., Uppenberg, J., Van den berg, S., Weigelt, J., Persson, C., Thorsell, A.G., Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B).
J.Biol.Chem., 286, 2011
2HW4
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CRYSTAL STRUCTURE OF HUMAN PHOSPHOHISTIDINE PHOSPHATASE
Descriptor:14 kDa phosphohistidine phosphatase, FORMIC ACID
Authors:Busam, R.D., Thorsell, A.G., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Holmberg Schiavone, L., Hogbom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Ogg, D., Stenmark, P., Sundstrom, M., Uppenberg, J., Van Den Berg, S., Weigelt, J., Persson, C., Hallberg, B.M., Structural Genomics Consortium (SGC)
Deposit date:2006-07-31
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:First structure of a eukaryotic phosphohistidine phosphatase
J.Biol.Chem., 281, 2006
2I4I
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CRYSTAL STRUCTURE OF HUMAN DEAD-BOX RNA HELICASE DDX3X
Descriptor:ATP-dependent RNA helicase DDX3X, ADENOSINE MONOPHOSPHATE
Authors:Hogbom, M., Karlberg, T., Arrowsmith, C., Berglund, H., Busam, R.D., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Johansson, I., Kotenyova, T., Magnusdottir, A., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Uppenberg, J., Van Den Berg, S., Wallden, K., Weigelt, J., Welin, M., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)
Deposit date:2006-08-22
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Conserved Domains 1 and 2 of the Human DEAD-box Helicase DDX3X in Complex with the Mononucleotide AMP
J.Mol.Biol., 372, 2007
2J2C
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE II (NT5C2, CN-II)
Descriptor:CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, SULFATE ION, ...
Authors:Wallden, K., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Karlberg, T., Kotenyova, T., Loppnau, P., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2006-08-16
Release date:2006-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Human Cytosolic 5'- Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
J.Biol.Chem., 282, 2007
2J4E
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THE ITP COMPLEX OF HUMAN INOSINE TRIPHOSPHATASE
Descriptor:INOSINE TRIPHOSPHATE PYROPHOSPHATASE, INOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Stenmark, P., Kursula, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmbergschiavone, L., Hogbom, M., Kotenyova, T., Landry, R., Loppnau, P., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Schuler, H., Van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.
Deposit date:2006-08-29
Release date:2006-09-20
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Human Inosine Triphosphatase: Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
J.Biol.Chem., 282, 2007
2J67
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THE TIR DOMAIN OF HUMAN TOLL-LIKE RECEPTOR 10 (TLR10)
Descriptor:TOLL LIKE RECEPTOR 10
Authors:Stenmark, P., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kotenyova, T., Magnusdottir, A., Nilsson, M.E., Nilsson-Ehle, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2006-09-26
Release date:2006-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of the Human Toll-Like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer.
J.Biol.Chem., 283, 2008
2IBN
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CRYSTAL STRUCTURE OF HUMAN MYO-INOSITOL OXYGENASE (MIOX)
Descriptor:Inositol oxygenase, FE (III) ION, SULFATE ION, ...
Authors:Hallberg, B.M., Busam, R.D., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hogbom, M., Holmberg-Schiavone, L., Johansson, I., Karlberg, T., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Ogg, D., Sagemark, J., Stenmark, P., Sundstrom, M., Uppenberg, J., Van Den Berg, S., Weigelt, J., Thorsell, A.G., Persson, C., Structural Genomics Consortium (SGC)
Deposit date:2006-09-11
Release date:2006-10-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Biophysical Characterization of Human myo-Inositol Oxygenase
J.Biol.Chem., 283, 2008
2J91
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CRYSTAL STRUCTURE OF HUMAN ADENYLOSUCCINATE LYASE IN COMPLEX WITH AMP
Descriptor:ADENYLOSUCCINATE LYASE, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
Authors:Stenmark, P., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Magnusdottir, A., Nilsson, M.E., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Uppsten, M., Thorsell, A.G., van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.
Deposit date:2006-11-01
Release date:2006-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Human Adenylosuccinate Lyase
To be Published
2NMP
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CRYSTAL STRUCTURE OF HUMAN CYSTATHIONINE GAMMA LYASE
Descriptor:Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE
Authors:Karlberg, T., Uppenberg, J., Arrowsmith, C., Berglund, H., Busam, R.D., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Hogbom, M., Johansson, I., Kotenyova, T., Magnusdottir, A., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., van-den-Berg, S., Wallden, K., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)
Deposit date:2006-10-23
Release date:2006-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S
J.Biol.Chem., 284, 2009
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