Author results

3L50
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THE CRYSTAL STRUCTURE OF HUMAN GLIA MATURATION FACTOR, GAMMA (GMFG)
Descriptor:Glia maturation factor gamma, CHLORIDE ION
Authors:Ugochukwu, E., Pilka, E., Krysztofinska, E., Hapka, E., Krojer, T., Muniz, J., Vollmar, M., Pike, A.C.W., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K.L., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2009-12-21
Release date:2010-02-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of human Glia Maturation Factor, Gamma (GMFG)
To be Published
2NZL
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CRYSTAL STRUCTURE OF HUMAN HYDROXYACID OXIDASE 1
Descriptor:Hydroxyacid oxidase 1, FLAVIN MONONUCLEOTIDE, GLYOXYLIC ACID
Authors:Ugochukwu, E., Kavanagh, K., Pilka, E., Berridge, G., Debreczeni, J.E., Papagrigoriou, E., Turnbull, A., Niesen, F., Gileadi, O., von Delft, F., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-11-24
Release date:2006-12-12
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structure of human hydroxyacid oxidase 1
To be Published
2B69
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CRYSTAL STRUCTURE OF HUMAN UDP-GLUCORONIC ACID DECARBOXYLASE
Descriptor:UDP-glucuronate decarboxylase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE
Authors:Ugochukwu, E., Dubinina, E., Kavanagh, K., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2005-09-30
Release date:2005-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Crystal Structure of Human UDP-glucoronic acid decarboxylase
To be Published
2F5Y
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN FROM HUMAN RGS-3
Descriptor:regulator of G-protein signalling 3 isoform 1, SULFATE ION
Authors:Ugochukwu, E., Berridge, G., Johansson, C., Smee, C., Savitsky, P., Burgess, N., Colebrook, S., Yang, X., Elkins, J., Doyle, D., Turnbull, A., Papagrigoriou, E., Debreczeni, J., Bunkoczi, G., Gorrec, F., von Delft, F., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
Deposit date:2005-11-28
Release date:2005-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Crystal Structure of the PDZ Domain from Human RGS-3
To be Published
2FE5
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THE CRYSTAL STRUCTURE OF THE SECOND PDZ DOMAIN OF HUMAN DLG3
Descriptor:Presynaptic protein SAP102, SULFATE ION, GLYCEROL
Authors:Ugochukwu, E., Phillips, C., Schoch, G., Berridge, G., Salah, E., Colebrook, S., Smee, C., Savitsky, P., Bray, J., Elkins, J., Doyle, D., Bunkoczi, G., Debreczeni, J., Turnbull, A., Gorrec, F., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
Deposit date:2005-12-15
Release date:2005-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Crystal Structure of the Second PDZ Domain of Human DLG3
To be Published
2PQ5
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CRYSTAL STRUCTURE OF DUAL SPECIFICITY PROTEIN PHOSPHATASE 13 (DUSP13)
Descriptor:Dual specificity protein phosphatase 13
Authors:Ugochukwu, E., Salah, E., Savitsky, P., Barr, A., Pantic, N., Niesen, F., Burgess-Brown, N., Berridge, G., Bunkoczi, G., Uppenberg, J., Pike, A.C.W., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., von Delft, F., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2007-05-01
Release date:2007-05-22
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Dual specificity protein phosphatase 13 (DUSP13).
To be Published
3F3S
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THE CRYSTAL STRUCTURE OF HUMAN LAMBDA-CRYSTALLIN, CRYL1
Descriptor:Lambda-crystallin homolog, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
Authors:Ugochukwu, E., Johansson, C., Yue, W.W., Kochan, G., Pilka, E., Kramm, A., Pike, A.C.W., Filippakopoulos, P., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2008-10-31
Release date:2008-11-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human Lambda-Crystallin, CRYL1
To be Published
3FLV
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THE CRYSTAL STRUCTURE OF HUMAN ACYL-COENZYMEA BINDING DOMAIN CONTAINING 5
Descriptor:Acyl-CoA-binding domain-containing protein 5, STEARIC ACID, COENZYME A, ...
Authors:Ugochukwu, E., Roos, A., Yue, W.W., Shafqat, N., Salah, E., Savitsky, P., Muniz, J.R.C., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2008-12-19
Release date:2009-02-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of human acyl-Coenzyme A binding domain containing 5
To be Published
3HMI
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THE CRYSTAL STRUCTURE OF HUMAN ABL2 IN COMPLEX WITH 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE
Descriptor:Tyrosine-protein kinase ABL2, 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE
Authors:Ugochukwu, E., Salah, E., Barr, A., Mahajan, P., Shrestha, B., Savitsky, P., Chaikuad, A., Allerston, C., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2009-05-29
Release date:2009-07-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The crystal structure of human ABL2 in complex with 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE
To be Published
3I2B
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THE CRYSTAL STRUCTURE OF HUMAN 6 PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE
Descriptor:6-pyruvoyl tetrahydrobiopterin synthase, 1,2-ETHANEDIOL, NICKEL (II) ION, ...
Authors:Ugochukwu, E., Cocking, R., Pilka, E., Yue, W.W., Bray, J.E., Chaikuad, A., Krojer, T., Muniz, J., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2009-06-29
Release date:2009-07-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of human 6 Pyruvoyl Tetrahydrobiopterin Synthase
To be Published
3IAR
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THE CRYSTAL STRUCTURE OF HUMAN ADENOSINE DEAMINASE
Descriptor:Adenosine deaminase, (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, NICKEL (II) ION, ...
Authors:Ugochukwu, E., Zhang, Y., Hapka, E., Yue, W.W., Bray, J.E., Muniz, J., Burgess-Brown, N., Chaikuad, A., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K.L., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2009-07-14
Release date:2009-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:The crystal structure of human adenosine deaminase
To be Published
3II0
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CRYSTAL STRUCTURE OF HUMAN GLUTAMATE OXALOACETATE TRANSAMINASE 1 (GOT1)
Descriptor:Aspartate aminotransferase, cytoplasmic, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Ugochukwu, E., Pilka, E., Cooper, C., Bray, J.E., Yue, W.W., Muniz, J., Chaikuad, A., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K.L., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2009-07-31
Release date:2009-08-11
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1)
To be Published
3IR3
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CRYSTAL STRUCTURE OF HUMAN 3-HYDROXYACYL-THIOESTER DEHYDRATASE 2 (HTD2)
Descriptor:3-hydroxyacyl-thioester dehydratase 2, MALONATE ION
Authors:Ugochukwu, E., Cocking, R., Burgess-Brown, N., Pilka, E., Muniz, J., Krojer, T., Chaikuad, A., Gileadi, O., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K.L., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2009-08-21
Release date:2009-09-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structure of human 3-hydroxyacyl-thioester dehydratase 2 (HTD2)
To be Published
3K1Z
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CRYSTAL STRUCTURE OF HUMAN HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN CONTAINING 3 (HDHD3)
Descriptor:Haloacid dehalogenase-like hydrolase domain-containing protein 3, 1,2-ETHANEDIOL, GLYCEROL
Authors:Ugochukwu, E., Guo, K., Yue, W.W., Pilka, E., Picaud, S., Muniz, J., Pike, A.C.W., Krojer, T., Gomes, M., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2009-09-29
Release date:2009-11-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure of Human Haloacid Dehalogenase-like Hydrolase Domain containing 3 (HDHD3)
To be Published
3KVO
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN HYDROXYSTEROID DEHYDROGENASE LIKE 2 (HSDL2)
Descriptor:Hydroxysteroid dehydrogenase-like protein 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Ugochukwu, E., Bhatia, C., Huang, J., Pilka, E., Muniz, J.R.C., Pike, A.C.W., Krojer, T., von Delft, F., Arrowsmith, C.H., Weigelt, J., Edwards, A., Bountra, C., Verdin, E.M., Oppermann, U., Kavanagh, K.L., Structural Genomics Consortium (SGC)
Deposit date:2009-11-30
Release date:2010-03-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of the catalytic domain of human Hydroxysteroid dehydrogenase like 2 (HSDL2)
To be Published
3MDZ
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CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE VII [ISOFORM 1], CA7
Descriptor:Carbonic anhydrase 7, ZINC ION, 6-ethoxy-1,3-benzothiazole-2-sulfonamide, ...
Authors:Ugochukwu, E., Shafqat, N., Pilka, E., Chaikuad, A., Krojer, T., Muniz, J., Kim, J., Bray, J., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., von Delft, F., Carpenter, E.P., Yue, W.W., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2010-03-31
Release date:2010-06-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Crystal Structure of Human Carbonic Anhydrase VII [isoform 1], CA7
to be published
3NR3
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CRYSTAL STRUCTURE OF HUMAN PERIPHERAL MYELIN PROTEIN 2
Descriptor:PMP2 protein, PALMITIC ACID, SULFATE ION, ...
Authors:Ugochukwu, E., Pilka, E., Phillips, C., Yue, W.W., Krojer, T., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K.L., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2010-06-30
Release date:2010-08-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of Human Peripheral Myelin Protein 2
To be Published
3PS4
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PDZ DOMAIN FROM HUMAN MICROTUBULE-ASSOCIATED SERINE/THREONINE-PROTEIN KINASE 1
Descriptor:Microtubule-associated serine/threonine-protein kinase 1, 1,2-ETHANEDIOL, IMIDAZOLE
Authors:Ugochukwu, E., Wang, J., Krojer, T., Muniz, J.R.C., Sethi, R., Pike, A.C.W., Roos, A., Salah, E., Cocking, R., Savitsky, P., Doyle, D.A., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S., Elkins, J.M., Structural Genomics Consortium (SGC)
Deposit date:2010-11-30
Release date:2010-12-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1
TO BE PUBLISHED
4DYL
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F-BAR DOMAIN OF HUMAN FES TYROSINE KINASE
Descriptor:Tyrosine-protein kinase Fes/Fps
Authors:Ugochukwu, E., Salah, E., Elkins, J., Barr, A., Krojer, T., Filippakopoulos, P., Weigelt, J., Arrowsmith, C.H., Edwards, A., Bountra, C., von Delft, F., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2012-02-29
Release date:2012-04-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:F-BAR domain of human FES tyrosine kinase
TO BE PUBLISHED
1Z6Z
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CRYSTAL STRUCTURE OF HUMAN SEPIAPTERIN REDUCTASE IN COMPLEX WITH NADP+
Descriptor:Sepiapterin reductase, SULFATE ION, CHLORIDE ION, ...
Authors:Ugochukwu, E., Kavanagh, K., Ng, S., Arrowsmith, C., Edwards, A., Sundstrom, M., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2005-03-23
Release date:2005-04-05
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Human Sepiapterin Reductase
To be Published
2DFD
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CRYSTAL STRUCTURE OF HUMAN MALATE DEHYDROGENASE TYPE 2
Descriptor:Malate dehydrogenase, D-MALATE, CHLORIDE ION, ...
Authors:Ugochukwu, E., Shafqat, N., Rojkova, A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-02-28
Release date:2006-03-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Human Malate Dehydrogenase Type 2
To be Published
2FVL
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CRYSTAL STRUCTURE OF HUMAN 3-ALPHA HYDROXYSTEROID/DIHYDRODIOL DEHYDROGENASE (AKR1C4) COMPLEXED WITH NADP+
Descriptor:Aldo-keto reductase family 1, member C4, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Ugochukwu, E., Smee, C., Guo, K., Lukacik, P., Kavanagh, K., Debreczeni, J.E., von Delft, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-01-31
Release date:2006-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human 3-alpha hydroxysteroid/dihydrodiol dehydrogenase (AKR1C4) complexed with NADP+
To be Published
2G0N
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THE CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP AND CHLORIDE
Descriptor:Ras-related C3 botulinum toxin substrate 3, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Ugochukwu, E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2006-02-13
Release date:2006-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
To be Published
2G3Y
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CRYSTAL STRUCTURE OF THE HUMAN SMALL GTPASE GEM
Descriptor:GTP-binding protein GEM, GUANOSINE-5'-DIPHOSPHATE
Authors:Ugochukwu, E., Soundararajan, M., Elkins, J., Gileadi, C., Schoch, G., Sobott, F., Fedorov, O., Bray, J., Pantic, N., Berridge, G., Burgess, N., Lee, W.H., Turnbull, A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2006-02-21
Release date:2006-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the human small GTPase GEM
To be Published
2OV2
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THE CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH THE CRIB DOMAIN OF HUMAN P21-ACTIVATED KINASE 4 (PAK4)
Descriptor:Ras-related C3 botulinum toxin substrate 3, Serine/threonine-protein kinase PAK 4, MAGNESIUM ION, ...
Authors:Ugochukwu, E., Yang, X., Elkins, J.M., Burgess-Brown, N., Bunkoczi, G., Debreczeni, J.E.D., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., von Delft, F., Knapp, S., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-02-12
Release date:2007-03-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of the human RAC3 in complex with the CRIB domain of human p21-activated kinase 4 (PAK4)
To be Published
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