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2WFF
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BU of 2wff by Molmil
Equine Rhinitis A Virus
Descriptor: P1
Authors:Fry, E.E, Tuthill, T.J, Harlos, K, Walter, T.S, Knowles, N.J, Gropelli, E, Rowlands, D.J, Stuart, D.I.
Deposit date:2009-04-05
Release date:2010-05-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Equine Rhinitis a Virus and its Low Ph Empty Particle: Clues Towards an Aphthovirus Entry Mechanism?
Plos Pathog., 5, 2009
2WS9
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BU of 2ws9 by Molmil
Equine Rhinitis A Virus at Low pH
Descriptor: P1
Authors:Fry, E.E, Tuthill, T.J, Harlos, K, Walter, T.S, Knowles, N.J, Gropelli, E, Rowlands, D.J, Stuart, D.I.
Deposit date:2009-09-04
Release date:2010-08-25
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Equine Rhinitis a Virus and its Low Ph Empty Particle: Clues Towards an Aphthovirus Entry Mechanism?
Plos Pathog., 5, 2009
3JB4
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BU of 3jb4 by Molmil
Structure of Ljungan virus: insight into picornavirus packaging
Descriptor: VP0, VP1, VP3
Authors:Zhu, L, Wang, X.X, Ren, J.S, Porta, C, Wenham, H, Ekstrom, J.-O, Panjwani, A, Knowles, N.J, Kotecha, A, Siebert, A, Lindberg, M, Fry, E.E, Rao, Z.H, Tuthill, T.J, Stuart, D.I.
Deposit date:2015-07-21
Release date:2015-10-21
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of Ljungan virus provides insight into genome packaging of this picornavirus.
Nat Commun, 6, 2015
5GKA
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BU of 5gka by Molmil
cryo-EM structure of human Aichi virus
Descriptor: Genome polyprotein, capsid protein VP0, capsid protein VP1
Authors:Zhu, L, Wang, X.X, Ren, J.S, Tuthill, T.J, Fry, E.E, Rao, Z.H, Stuart, D.I.
Deposit date:2016-07-04
Release date:2016-09-21
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of human Aichi virus and implications for receptor binding
Nat Microbiol, 1, 2016
2XBO
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BU of 2xbo by Molmil
Equine Rhinitis A Virus in Complex with its Sialic Acid Receptor
Descriptor: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, P1
Authors:Fry, E.E, Tuthill, T.J, Harlos, K, Walter, T.S, Rowlands, D.J, Stuart, D.I.
Deposit date:2010-04-14
Release date:2010-09-22
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4 Å)
Cite:The Crystal Structure of Equine Rhinitis a Virus in Complex with its Sialic Acid Receptor.
J.Gen.Virol., 91, 2010
6THD
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BU of 6thd by Molmil
Multiple Genomic RNA-Coat Protein Contacts Play Vital Roles in the Assembly of Infectious Enterovirus-E
Descriptor: Genome polyprotein, MYRISTIC ACID, SULFATE ION
Authors:Chandler-Bostock, R, Mata, C.P, Bingham, R, Dykeman, E.J, Meng, B, Tuthill, T.J, Rowlands, D.J, Ranson, N.A, Twarock, R, Stockley, P.G.
Deposit date:2019-11-19
Release date:2020-12-09
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (2.23 Å)
Cite:Assembly of infectious enteroviruses depends on multiple, conserved genomic RNA-coat protein contacts.
Plos Pathog., 16, 2020
6THN
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BU of 6thn by Molmil
Multiple Genomic RNA-Coat Protein Contacts Play Vital Roles in the Assembly of Infectious Enterovirus-E symmetry expansion+2fold focused classification
Descriptor: Genome polyprotein, MYRISTIC ACID, RNA Peak 9 Bernoulli Plot, ...
Authors:Chandler-Bostock, R, Mata, C.P, Bingham, R, Dykeman, E.J, Meng, B, Tuthill, T.J, Rowlands, D.J, Ranson, N.A, Twarock, R, Stockley, P.G.
Deposit date:2019-11-20
Release date:2020-12-09
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Assembly of infectious enteroviruses depends on multiple, conserved genomic RNA-coat protein contacts.
Plos Pathog., 16, 2020
5MU6
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BU of 5mu6 by Molmil
Human N-myristoyltransferase (NMT1) with Myristoyl-CoA and IMP-1088 inhibitor bound
Descriptor: 1-[5-[3,4-bis(fluoranyl)-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-1-methyl-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ...
Authors:Perez-Dorado, I, Bell, A.S, Tate, E.W.
Deposit date:2017-01-12
Release date:2018-02-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus.
Nat Chem, 10, 2018
6FFA
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BU of 6ffa by Molmil
FMDV Leader protease bound to substrate ISG15
Descriptor: GLYCEROL, Lbpro, SULFATE ION, ...
Authors:Swatek, K.N, Pruneda, J.N, Komander, D.
Deposit date:2018-01-05
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7B3Y
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BU of 7b3y by Molmil
Structure of a nanoparticle for a COVID-19 vaccine candidate
Descriptor: Fibronectin binding protein,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase
Authors:Duyvesteyn, H.M.E, Stuart, D.I.
Deposit date:2020-12-01
Release date:2021-01-13
Last modified:2021-02-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses.
Nat Commun, 12, 2021
5O6J
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BU of 5o6j by Molmil
Human NMT1 in complex with myristoyl-CoA and inhibitor IMP-1031
Descriptor: 1-[5-[3-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-1-methyl-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, Glycylpeptide N-tetradecanoyltransferase 1, MAGNESIUM ION, ...
Authors:Brannigan, J.A, Wilkinson, A.J.
Deposit date:2017-06-06
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus.
Nat Chem, 10, 2018
5O6H
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BU of 5o6h by Molmil
Human NMT1 in complex with myristoyl-CoA and inhibitor IMP-917
Descriptor: 1-[5-[4-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-2~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Brannigan, J.A, Wilkinson, A.J.
Deposit date:2017-06-06
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus.
Nat Chem, 10, 2018
5O48
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BU of 5o48 by Molmil
P.vivax NMT with an aminomethylindazole inhibitor bound
Descriptor: 1-[5-(4-fluoranyl-2-methyl-phenyl)-1~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, 2-oxopentadecyl-CoA, CHLORIDE ION, ...
Authors:Brannigan, J.A, Wilkinson, A.J.
Deposit date:2017-05-26
Release date:2018-05-16
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus.
Nat Chem, 10, 2018
5O4V
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BU of 5o4v by Molmil
P.vivax NMT with aminomethylindazole and quinoline inhibitors bound
Descriptor: 1-[5-(4-fluoranyl-2-methyl-phenyl)-1~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, 2-oxopentadecyl-CoA, CHLORIDE ION, ...
Authors:Brannigan, J.A, Wilkinson, A.J.
Deposit date:2017-05-31
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus.
Nat Chem, 10, 2018
5OYI
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BU of 5oyi by Molmil
FMDV A10 dissociated pentamer
Descriptor: Genome polyprotein
Authors:Kotecha, A, Malik, N, Stuart, D.I.
Deposit date:2017-09-09
Release date:2017-09-20
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation.
PLoS Pathog., 13, 2017
5OWX
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BU of 5owx by Molmil
Inside-out FMDV A10 capsid
Descriptor: Genome polyprotein
Authors:Kotecha, A, Malik, N, Fry, E.E, Stuart, D.I.
Deposit date:2017-09-04
Release date:2017-09-20
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation.
PLoS Pathog., 13, 2017

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