Author results

6CNW
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STRUCTURE OF HUMANIZED SINGLE DOMAIN ANTIBODY SD84
Descriptor:humanized antibody SD84h, ACETATE ION, DI(HYDROXYETHYL)ETHER
Authors:Luo, J., Obmolova, O.
Deposit date:2018-03-09
Release date:2018-11-14
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
5VZR
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CRYSTAL STRUCTURE OF MERS-COV NEUTRALIZING ANTIBODY G4 FAB
Descriptor:G4 antibody heavy chain, G4 antibody light chain, GLYCEROL
Authors:Wang, N., Wrapp, D., McLellan, J.S.
Deposit date:2017-05-29
Release date:2017-08-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6OBZ
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CRYSTAL STRUCTURE OF FLUA-20 FAB
Descriptor:Heavy chain of FluA-20 Fab, Light chain of FluA-20 Fab, Immunoglobulin light chain
Authors:Wilson, I.A., Lang, S.
Deposit date:2019-03-21
Release date:2019-05-15
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface.
Cell, 177, 2019
6CJK
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ANTI HIV FAB 10A
Descriptor:Immunoglobulin Fab light chain, Immunoglobulin Fab heavy chain, ACETATE ION, ...
Authors:Hangartner, L., Ward, A.B., Wilson, I.A., Oyen, D.
Deposit date:2018-02-26
Release date:2018-08-15
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (1.795 Å)
Cite:Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization.
Immunity, 49, 2018
5UMN
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CRYSTAL STRUCTURE OF C05 VPGSGW MUTANT BOUND TO H3 INFLUENZA HEMAGGLUTININ, HA1 SUBUNIT
Descriptor:Hemagglutinin, Antibody C05 VPGSGW mutant, heavy chain, ...
Authors:Wu, N.C., Wilson, I.A.
Deposit date:2017-01-27
Release date:2017-05-24
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity.
Nat Commun, 8, 2017
5VYH
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CRYSTAL STRUCTURE OF MERS-COV S1 N-TERMINAL DOMAIN
Descriptor:S protein, N-ACETYL-D-GLUCOSAMINE, FOLIC ACID, ...
Authors:Wang, N., Wrapp, D., Pallesen, J., Ward, A.B., McLellan, J.S.
Deposit date:2017-05-25
Release date:2017-08-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6FYS
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STRUCTURE OF SINGLE DOMAIN ANTIBODY SD83
Descriptor:Single domain antibody SD83, 1,2-ETHANEDIOL
Authors:Laursen, N.S., Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6CK8
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CRYSTAL STRUCTURE OF ANTI-INFLUENZA SINGLE-DOMAIN LLAMA ANTIBODY SD38
Descriptor:Llama antibody SD38, SULFATE ION, PENTAETHYLENE GLYCOL, ...
Authors:Zhu, X., Wilson, I.A.
Deposit date:2018-02-27
Release date:2018-11-14
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6PXG
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CRYSTAL STRUCTURE OF MERS-COV NEUTRALIZING ANTIBODY G2 FAB
Descriptor:G2 Fab Heavy Chain, G2 Fab Light chain
Authors:Wang, N., McLellan, J.S.
Deposit date:2019-07-26
Release date:2019-09-25
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
Cell Rep, 28, 2019
6FYW
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STRUCTURE OF B/BRISBANE/60/2008 INFLUENZA HEMAGGLUTININ IN COMPLEX WITH SD83
Descriptor:Hemagglutinin, Single domain antibody SD83, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Laursen, N.S., Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6PXH
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CRYSTAL STRUCTURE OF MERS-COV S1-NTD BOUND WITH G2 FAB
Descriptor:MERS-CoV S1-NTD, G2 heavy chain, G2 light chain, ...
Authors:Wang, N., McLellan, J.S.
Deposit date:2019-07-26
Release date:2019-09-25
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
Cell Rep, 28, 2019
6FYU
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STRUCTURE OF H7(A/SHANGHAI/2/2013) INFLUENZA HEMAGGLUTININ IN COMPLEX SD36
Descriptor:Hemaggluinin HA1, Hemagglutinin, Single domain antibody SD36, ...
Authors:Laursen, N.S., Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.643 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYT
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STRUCTURE OF H1 (A/SOLOMON ISLANDS/3/06) INFLUENZA HEMAGGLUTININ IN COMPLEX WITH SD38
Descriptor:Hemagglutinin, Single domain antibody SD38, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Laursen, N.S., Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6OC3
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CRYSTAL STRUCTURE OF FLUA-20 FAB IN COMPLEX WITH THE HEAD DOMAIN OF H1 (A/SOLOMON ISLANDS/3/2006)
Descriptor:Heavy chain of FluA-20 Fab, Light chain of FluA-20 Fab, Hemagglutinin, ...
Authors:Wilson, I.A., Lang, S.
Deposit date:2019-03-21
Release date:2019-05-15
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface.
Cell, 177, 2019
6CRV
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, C3 SYMMETRY
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRZ
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SARS SPIKE GLYCOPROTEIN, TRYPSIN-CLEAVED, STABILIZED VARIANT, C3 SYMMETRY
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6MLM
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H7 HA0 IN COMPLEX WITH FV FROM H7.5 IGG
Descriptor:Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, Heavy chain Fv of H7.5 Fab, ...
Authors:Pallesen, J., Turner, H.L., Ward, A.B.
Deposit date:2018-09-27
Release date:2019-02-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains.
PLoS Biol., 17, 2019
5W9I
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL, ...
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6CS0
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SARS SPIKE GLYCOPROTEIN, TRYPSIN-CLEAVED, STABILIZED VARIANT, ONE S1 CTD IN AN UPWARDS CONFORMATION
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRW
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, SINGLE UPWARDS S1 CTD CONFORMATION
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRX
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, TWO S1 CTDS IN THE UPWARDS CONFORMATION
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
5W9H
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:MERS S, G4 VH, G4 VL, ...
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9P
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5I08
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PREFUSION STRUCTURE OF A HUMAN CORONAVIRUS SPIKE PROTEIN
Descriptor:Spike glycoprotein, envelope glycoprotein chimera
Authors:Kirchdoerfer, R.N., Cottrell, C.A., Wang, N., Pallesen, J., Yassine, H.M., Turner, H.L., Corbett, K.S., Graham, B.S., McLellan, J.S., Ward, A.B.
Deposit date:2016-02-03
Release date:2016-03-02
Last modified:2016-04-13
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Pre-fusion structure of a human coronavirus spike protein.
Nature, 531, 2016
6CNV
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INFLUENZA B/BRISBANE HEMAGGLUTININ FAB CR9115 SD84H COMPLEX
Descriptor:Hemagglutinin, Envelope glycoprotein, SD84h, ...
Authors:Luo, J., Obmolova, G.
Deposit date:2018-03-09
Release date:2018-11-14
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
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