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6CHA
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STRUCTURE OF A TETRAHEDRAL TRANSITION STATE COMPLEX OF ALPHA-*CHYMOTRYPSIN AT 1.8-*ANGSTROMS RESOLUTION
Descriptor:ALPHA-CHYMOTRYPSIN A, PHENYLETHANE BORONIC ACID
Authors:Tulinsky, A., Blevins, R.A.
Deposit date:1987-02-06
Release date:1987-04-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a tetrahedral transition state complex of alpha-chymotrypsin dimer at 1.8-A resolution.
J.Biol.Chem., 262, 1987
1KGA
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STRUCTURE OF 2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE AT 2.8 ANGSTROMS RESOLUTION
Descriptor:2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE
Authors:Tulinsky, A.
Deposit date:1978-08-21
Release date:1978-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of 2-keto-3-deoxy-6-phosphogluconate aldolase at 2 . 8 A resolution.
J.Mol.Biol., 162, 1982
1PK4
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CRYSTAL AND MOLECULAR STRUCTURE OF HUMAN PLASMINOGEN KRINGLE 4 REFINED AT 1.9-ANGSTROMS RESOLUTION
Descriptor:PLASMINOGEN KRINGLE 4, SULFATE ION
Authors:Tulinsky, A., Mulichak, A.M.
Deposit date:1991-07-18
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal and molecular structure of human plasminogen kringle 4 refined at 1.9-A resolution.
Biochemistry, 30, 1991
2PK4
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THE REFINED STRUCTURE OF THE EPSILON-AMINOCAPROIC ACID COMPLEX OF HUMAN PLASMINOGEN KRINGLE
Descriptor:HUMAN PLASMINOGEN KRINGLE 4, 6-AMINOHEXANOIC ACID
Authors:Tulinsky, A., Wu, T.-P.
Deposit date:1991-07-18
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The refined structure of the epsilon-aminocaproic acid complex of human plasminogen kringle 4.
Biochemistry, 30, 1991
1HXF
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HUMAN THROMBIN COMPLEX WITH HIRUDIN VARIANT
Descriptor:THROMBIN, HIRUDIN VARIANT
Authors:Tulinsky, A., Zhang, E.
Deposit date:1996-09-09
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The molecular environment of the Na+ binding site of thrombin.
Biophys.Chem., 63, 1997
1DIT
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COMPLEX OF A DIVALENT INHIBITOR WITH THROMBIN
Descriptor:ALPHA-THROMBIN, PEPTIDE INHIBITOR CVS995
Authors:Tulinsky, A., Krishnan, R.
Deposit date:1995-07-20
Release date:1996-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Synthesis, structure, and structure-activity relationships of divalent thrombin inhibitors containing an alpha-keto-amide transition-state mimetic.
Protein Sci., 5, 1996
2HPP
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STRUCTURES OF THE NONCOVALENT COMPLEXES OF HUMAN AND BOVINE PROTHROMBIN FRAGMENT 2 WITH HUMAN PPACK-THROMBIN
Descriptor:ALPHA-THROMBIN LIGHT CHAIN, ALPHA-THROMBIN HEAVY CHAIN, Prothrombin, ...
Authors:Tulinsky, A., Padmanabhan, K.
Deposit date:1993-04-28
Release date:1994-01-31
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin.
Biochemistry, 32, 1993
2HPQ
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STRUCTURES OF THE NONCOVALENT COMPLEXES OF HUMAN AND BOVINE PROTHROMBIN FRAGMENT 2 WITH HUMAN PPACK-THROMBIN
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), Prothrombin, ...
Authors:Tulinsky, A., Padmanabhan, K.
Deposit date:1993-04-28
Release date:1994-01-31
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin.
Biochemistry, 32, 1993
1CEA
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THE STRUCTURE OF THE NON-COVALENT COMPLEX OF RECOMBINANT KRINGLE 1 DOMAIN OF HUMAN PLASMINOGEN WITH EACA (EPSILON-AMINOCAPROIC ACID)
Descriptor:PLASMINOGEN, 6-AMINOHEXANOIC ACID
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1995-12-03
Release date:1996-04-03
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid.
Biochemistry, 35, 1996
1CEB
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THE STRUCTURE OF THE NON-COVALENT COMPLEX OF RECOMBINANT KRINGLE 1 DOMAIN OF HUMAN PLASMINOGEN WITH AMCHA (TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID)
Descriptor:PLASMINOGEN, TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1995-12-03
Release date:1996-04-03
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid.
Biochemistry, 35, 1996
1FPC
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ACTIVE SITE MIMETIC INHIBITION OF THROMBIN
Descriptor:thrombin, Hirudin, amino{[(4S)-4-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)-5-(4-ethylpiperidin-1-yl)-5-oxopentyl]amino}methaniminium
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1994-10-16
Release date:1995-02-27
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Active-site mimetic inhibition of thrombin.
Acta Crystallogr.,Sect.D, 51, 1995
1HAG
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THE ISOMORPHOUS STRUCTURES OF PRETHROMBIN2, HIRUGEN-AND PPACK-THROMBIN: CHANGES ACCOMPANYING ACTIVATION AND EXOSITE BINDING TO THROMBIN
Descriptor:PRETHROMBIN 2, HIRUGEN, N-ACETYL-D-GLUCOSAMINE
Authors:Tulinsky, A., Vijayalakshmi, J.
Deposit date:1994-06-27
Release date:1994-12-20
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
Protein Sci., 3, 1994
1HAH
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THE ISOMORPHOUS STRUCTURES OF PRETHROMBIN2, HIRUGEN-AND PPACK-THROMBIN: CHANGES ACCOMPANYING ACTIVATION AND EXOSITE BINDING TO THROMBIN
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUGEN, ...
Authors:Tulinsky, A., Vijayalakshmi, J.
Deposit date:1994-06-27
Release date:1994-12-20
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
Protein Sci., 3, 1994
1HAI
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THE ISOMORPHOUS STRUCTURES OF PRETHROMBIN2, HIRUGEN-AND PPACK-THROMBIN: CHANGES ACCOMPANYING ACTIVATION AND EXOSITE BINDING TO THROMBIN
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Tulinsky, A., Vijayalakshmi, J.
Deposit date:1994-06-27
Release date:1994-12-20
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
Protein Sci., 3, 1994
1HGT
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STRUCTURE OF THE HIRUGEN AND HIRULOG 1 COMPLEXES OF ALPHA-THROMBIN
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUGEN
Authors:Tulinsky, A., Skrzypczak-Jankun, E.
Deposit date:1991-06-03
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the hirugen and hirulog 1 complexes of alpha-thrombin.
J.Mol.Biol., 221, 1991
1HXE
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SERINE PROTEASE
Descriptor:THROMBIN, HIRUDIN VARIANT-1, RUBIDIUM ION
Authors:Tulinsky, A., Zhang, E.
Deposit date:1995-12-07
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The molecular environment of the Na+ binding site of thrombin.
Biophys.Chem., 63, 1997
1NRN
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CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), RECEPTOR BASED PEPTIDE NRS
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
1NRO
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CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), RECEPTOR BASED PEPTIDE NRP
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
1NRP
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CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), RECEPTOR BASED PEPTIDE NR'S
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
1NRQ
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CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), RECEPTOR BASED PEPTIDE D-FPR'S
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
1NRR
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CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor:Thrombin light chain, Thrombin heavy chain, Proteinase-activated receptor 1, ...
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
1NRS
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CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), RECEPTOR BASED PEPTIDE NRP, ...
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
2HGT
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STRUCTURE OF THE HIRUGEN AND HIRULOG 1 COMPLEXES OF ALPHA-THROMBIN
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), Hirulog
Authors:Tulinsky, A., Carperos, V.
Deposit date:1991-06-03
Release date:1994-01-31
Last modified:2016-11-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the hirugen and hirulog 1 complexes of alpha-thrombin.
J.Mol.Biol., 221, 1991
2HNT
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CRYSTALLOGRAPHIC STRUCTURE OF HUMAN GAMMA-THROMBIN
Descriptor:GAMMA-THROMBIN
Authors:Tulinsky, A.
Deposit date:1994-08-23
Release date:1994-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic structure of human gamma-thrombin.
J.Biol.Chem., 269, 1994
2SPT
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DIFFERENCES IN THE METAL ION STRUCTURE BETWEEN SR-AND CA-PROTHROMBIN FRAGMENT 1
Descriptor:PROTHROMBIN, N-ACETYL-D-GLUCOSAMINE, STRONTIUM ION
Authors:Tulinsky, A.
Deposit date:1994-02-01
Release date:1994-05-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Differences in the metal ion structure between Sr- and Ca-prothrombin fragment 1.
Biochemistry, 33, 1994