2A1J
 
 | | Crystal Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1 | | Descriptor: | DNA excision repair protein ERCC-1, DNA repair endonuclease XPF, MERCURY (II) ION | | Authors: | Tsodikov, O.V, Enzlin, J.H, Scharer, O.D, Ellenberger, T. | | Deposit date: | 2005-06-20 | | Release date: | 2005-08-02 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A1I
 | | Crystal Structure of the Central Domain of Human ERCC1 | | Descriptor: | DNA excision repair protein ERCC-1, MERCURY (II) ION | | Authors: | Tsodikov, O.V, Enzlin, J.H, Scharer, O.D, Ellenberger, T. | | Deposit date: | 2005-06-20 | | Release date: | 2005-08-02 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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3PVP
 | | Structure of Mycobacterium tuberculosis DnaA-DBD in complex with box2 DNA | | Descriptor: | Chromosomal replication initiator protein dnaA, DNA (5'-D(*CP*GP*TP*TP*AP*TP*CP*CP*AP*CP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*GP*TP*GP*GP*AP*TP*AP*AP*CP*G)-3') | | Authors: | Tsodikov, O.V, Biswas, T. | | Deposit date: | 2010-12-07 | | Release date: | 2011-05-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and Thermodynamic Signatures of DNA Recognition by Mycobacterium tuberculosis DnaA.
J.Mol.Biol., 410, 2011
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3PVV
 | | Structure of Mycobacterium tuberculosis DnaA-DBD in complex with box1 DNA | | Descriptor: | Chromosomal replication initiator protein dnaA, DNA (5'-D(*CP*GP*TP*TP*GP*TP*CP*CP*AP*CP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*GP*TP*GP*GP*AP*CP*AP*AP*CP*G)-3') | | Authors: | Tsodikov, O.V, Biswas, T. | | Deposit date: | 2010-12-07 | | Release date: | 2011-05-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and Thermodynamic Signatures of DNA Recognition by Mycobacterium tuberculosis DnaA.
J.Mol.Biol., 410, 2011
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2JNW
 | | Solution structure of a ERCC1-XPA heterodimer | | Descriptor: | DNA excision repair protein ERCC-1, DNA-repair protein complementing XP-A cells | | Authors: | Tsodikov, O.V, Ivanov, D, Orelli, B, Staresincic, L, Scharer, O.D, Wagner, G. | | Deposit date: | 2007-02-07 | | Release date: | 2007-10-30 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA
Embo J., 26, 2007
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4RVH
 | | Crystal structure of MtmC in complex with SAH and TDP-4-keto-D-olivose | | Descriptor: | D-mycarose 3-C-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | | Authors: | Tsodikov, O.V, Hou, C, Chen, J.-M, Rohr, J. | | Deposit date: | 2014-11-26 | | Release date: | 2015-01-28 | | Last modified: | 2015-05-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain.
Biochemistry, 54, 2015
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4RVG
 | | Crystal structure of MtmC in complex with SAM and TDP | | Descriptor: | ACETATE ION, D-mycarose 3-C-methyltransferase, S-ADENOSYLMETHIONINE, ... | | Authors: | Tsodikov, O.V, Hou, C, Chen, J.-M, Rohr, J. | | Deposit date: | 2014-11-26 | | Release date: | 2015-01-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain.
Biochemistry, 54, 2015
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4RVD
 | | Crystal structure of MtmC in complex with SAM | | Descriptor: | ACETATE ION, D-mycarose 3-C-methyltransferase, S-ADENOSYLMETHIONINE, ... | | Authors: | Tsodikov, O.V, Hou, C, Chen, J.-M, Rohr, J. | | Deposit date: | 2014-11-26 | | Release date: | 2015-01-28 | | Last modified: | 2015-05-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain.
Biochemistry, 54, 2015
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4RVF
 | | Crystal structure of MtmC in complex with TDP | | Descriptor: | D-mycarose 3-C-methyltransferase, THYMIDINE-5'-DIPHOSPHATE, ZINC ION | | Authors: | Tsodikov, O.V, Hou, C, Chen, J.-M, Rohr, J. | | Deposit date: | 2014-11-26 | | Release date: | 2015-01-28 | | Last modified: | 2015-05-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain.
Biochemistry, 54, 2015
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3HYC
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2R8Z
 | | Crystal structure of YrbI phosphatase from Escherichia coli in complex with a phosphate and a calcium ion | | Descriptor: | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, CALCIUM ION, PHOSPHATE ION | | Authors: | Tsodikov, O.V, Aggarwal, P, Rubin, J.R, Stuckey, J.A, Woodard, R.W, Biswas, T. | | Deposit date: | 2007-09-11 | | Release date: | 2008-09-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
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2R8X
 | | Crystal structure of YrbI phosphatase from Escherichia coli | | Descriptor: | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, CHLORIDE ION | | Authors: | Tsodikov, O.V, Aggarwal, P, Rubin, J.R, Stuckey, J.A, Woodard, R.W, Biswas, T. | | Deposit date: | 2007-09-11 | | Release date: | 2008-09-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
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2R8Y
 | | Crystal structure of YrbI phosphatase from Escherichia coli in a complex with Ca | | Descriptor: | CALCIUM ION, CHLORIDE ION, YrbI from Escherichia coli | | Authors: | Tsodikov, O.V, Aggarwal, P, Rubin, J.R, Stuckey, J.A, Woodard, R.W, Biswas, T. | | Deposit date: | 2007-09-11 | | Release date: | 2008-09-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
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2R8E
 | | Crystal structure of YrbI from Escherichia coli in complex with Mg | | Descriptor: | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, CHLORIDE ION, MAGNESIUM ION | | Authors: | Tsodikov, O.V, Aggarwal, P, Rubin, J.R, Stuckey, J.A, Woodard, R, Biswas, T. | | Deposit date: | 2007-09-10 | | Release date: | 2008-09-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
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4Z2Y
 | | Crystal structure of methyltransferase CalO6 | | Descriptor: | CalO6, MERCURY (II) ION | | Authors: | Hou, C, Garneau-Tsodikova, S, Tsodikov, O.V. | | Deposit date: | 2015-03-30 | | Release date: | 2015-07-22 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Crystal structure of O-methyltransferase CalO6 from the calicheamicin biosynthetic pathway: a case of challenging structure determination at low resolution.
Bmc Struct.Biol., 15, 2015
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7JSA
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7JSL
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3U9F
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3U9B
 | | Structure of apo-CATI | | Descriptor: | Chloramphenicol acetyltransferase | | Authors: | Biswas, T, Garneau-Tsodikova, S, Tsodikov, O.V. | | Deposit date: | 2011-10-18 | | Release date: | 2012-02-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The structural basis for substrate versatility of chloramphenicol acetyltransferase CAT(I).
Protein Sci., 21, 2012
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7V0B
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7V0D
 | | Crystal structure of halogenase CtcP from Kitasatospora aureofaciens | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Hou, C, Tsodikov, O.V. | | Deposit date: | 2022-05-10 | | Release date: | 2023-05-17 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structures and complex formation of halogenase CtcP and FAD reductase CtcQ from the chlortetracycline biosynthetic pathway
To Be Published
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3R1K
 | | Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis H37Rv in complex with CoA and an acetamide moiety | | Descriptor: | ACETAMIDE, COENZYME A, Enhanced intracellular survival protein | | Authors: | Biswas, T, Chen, W, Garneau-Tsodikova, S, Tsodikov, O.V. | | Deposit date: | 2011-03-10 | | Release date: | 2011-06-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB.
Proc.Natl.Acad.Sci.USA, 108, 2011
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6DWT
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6DXJ
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6DY5
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