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3PX7
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BU of 3px7 by Molmil
Crystal Structure of covalent complex of topoisomerase 1A with substrate
Descriptor: DNA 5'-D(*A*AP*TP*GP*CP*GP*CP*T)-3', DNA 5'-D(*TP*TP*GP*GP*G)-3', DNA topoisomerase, ...
Authors:Zhang, Z, Tse-dinh, Y.C, Cheng, B.
Deposit date:2010-12-09
Release date:2011-04-20
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of E. coli Topoisomerase I Trapped as Covalent Complex Intermediate with Cleaved DNA
To be Published
4RUL
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BU of 4rul by Molmil
Crystal structure of full-length E.Coli topoisomerase I in complex with ssDNA
Descriptor: DNA topoisomerase 1, GLYCEROL, SULFATE ION, ...
Authors:Tan, K, Chen, B, Tse-Dinh, Y.C.
Deposit date:2014-11-20
Release date:2015-11-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for suppression of hypernegative DNA supercoiling by E. coli topoisomerase I.
Nucleic Acids Res., 43, 2015
8TFG
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BU of 8tfg by Molmil
1.88A CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TOPOISOMERASE I
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, DNA topoisomerase 1
Authors:Tan, K, Tse-Dinh, Y.C.
Deposit date:2023-07-11
Release date:2023-08-09
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:1.88A CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TOPOISOMERASE I
To Be Published
5D5H
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BU of 5d5h by Molmil
Crystal structure of Mycobacterium tuberculosis Topoisomerase I
Descriptor: ACETATE ION, DNA topoisomerase 1, GLYCEROL, ...
Authors:Tan, K, Cheng, B, Tse-Dinh, Y.C.
Deposit date:2015-08-10
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Insights from the Structure of Mycobacterium tuberculosis Topoisomerase I with a Novel Protein Fold.
J.Mol.Biol., 428, 2016
6PCM
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BU of 6pcm by Molmil
Crystal Structure of Mycobacterium smegmatis Topoisomerase I with ssDNA bound to both N- and C-terminal domains
Descriptor: DNA (5'-D(P*AP*GP*TP*GP*AP*GP*CP*GP*AP*GP*CP*TP*TP*CP*CP*GP*CP*TP*TP*GP*AP*CP*TP*T)-3'), DNA topoisomerase 1, SULFATE ION
Authors:Tan, K, Cao, N, Tse-Dinh, Y.C.
Deposit date:2019-06-17
Release date:2020-03-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.107 Å)
Cite:Mechanistic insights from structure of Mycobacterium smegmatis topoisomerase I with ssDNA bound to both N- and C-terminal domains.
Nucleic Acids Res., 48, 2020
5UJY
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BU of 5ujy by Molmil
The structure of Mycobacterium tuberculosis topoisomerase I from the 2nd crystal form
Descriptor: DNA topoisomerase 1
Authors:Cao, N, Tan, K, Tse-Dinh, Y.C.
Deposit date:2017-01-19
Release date:2018-01-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site.
Nucleic Acids Res., 46, 2018
5UJ1
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BU of 5uj1 by Molmil
Crystal structure of Mycobacterium tuberculosis Topoisomerase I at 2.15A resolution limit
Descriptor: DNA topoisomerase 1, SULFATE ION
Authors:Cao, N, Tan, K, Tse-Dinh, Y.C.
Deposit date:2017-01-16
Release date:2018-01-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.153 Å)
Cite:Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site.
Nucleic Acids Res., 46, 2018
8CZQ
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BU of 8czq by Molmil
The crystal structure of MtbTOP1 in complex with both G- and T-segments
Descriptor: ACETATE ION, DNA (5'-D(*CP*TP*TP*CP*CP*GP*CP*TP*TP*GP*AP*C)-3'), DNA topoisomerase 1, ...
Authors:Tan, K, Tse-Dinh, Y.-C.
Deposit date:2022-05-25
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:The interaction between transport-segment DNA and topoisomerase IA-crystal structure of MtbTOP1 in complex with both G- and T-segments.
Nucleic Acids Res., 51, 2023
1YUA
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BU of 1yua by Molmil
C-TERMINAL DOMAIN OF ESCHERICHIA COLI TOPOISOMERASE I
Descriptor: TOPOISOMERASE I
Authors:Yu, L, Zhu, C.-X, Tse-Dinh, Y.-C, Fesik, S.W.
Deposit date:1995-03-02
Release date:1996-03-08
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of the C-terminal single-stranded DNA-binding domain of Escherichia coli topoisomerase I.
Biochemistry, 34, 1995
6CQI
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BU of 6cqi by Molmil
2.42A Crystal structure of Mycobacterium tuberculosis Topoisomerase I in complex with an oligonucleotide MTS2-11
Descriptor: ACETATE ION, DNA (5'-D(P*TP*TP*CP*CP*GP*CP*TP*TP*GP*A)-3'), DNA topoisomerase 1, ...
Authors:Cao, N, Thirunavukkarasu, A, Tan, K, Tse-Dinh, Y.-C.
Deposit date:2018-03-15
Release date:2018-05-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site.
Nucleic Acids Res., 46, 2018
6CQ2
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BU of 6cq2 by Molmil
Crystal structure of Mycobacterium tuberculosis Topoisomerase I in complex with oligonucleotide MTS2-12 and Magnesium
Descriptor: DNA (5'-D(P*TP*TP*CP*CP*GP*CP*TP*TP*GP*A)-3'), DNA topoisomerase 1, MAGNESIUM ION, ...
Authors:Cao, N, Thirunavukkaraus, A, Tan, K, Tse-Dinh, Y.-C.
Deposit date:2018-03-14
Release date:2018-05-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site.
Nucleic Acids Res., 46, 2018

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