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1S1J
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CRYSTAL STRUCTURE OF ZIPA IN COMPLEX WITH INDOLOQUINOLIZIN INHIBITOR 1
Descriptor:Cell division protein zipA, (12bS)-1,2,3,4,12,12b-hexahydroindolo[2,3-a]quinolizin-7(6H)-one
Authors:Jenning, L.D., Foreman, K.W., Rush III, T.S., Tsao, D.H., Mosyak, L., Li, Y., Sukhdeo, M.N., Ding, W., Dushin, E.G., Kenney, C.H., Moghazeh, S.L., Peterson, P.J., Ruzin, A.V., Tuckman, M., Sutherland, A.G.
Deposit date:2004-01-06
Release date:2004-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction
Bioorg.Med.Chem.Lett., 14, 2004
1S1S
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CRYSTAL STRUCTURE OF ZIPA IN COMPLEX WITH INDOLOQUINOLIZIN 10B
Descriptor:Cell division protein zipA, N-{3-[(12bS)-7-oxo-1,3,4,6,7,12b-hexahydroindolo[2,3-a]quinolizin-12(2H)-yl]propyl}propane-2-sulfonamide
Authors:Jennings, L.D., Foreman, K.W., Rush III, T.S., Tsao, D.H., Mosyak, L., Li, Y., Sukhdeo, M.N., Ding, W., Dushin, E.G., Kenny, C.H., Moghazeh, S.L., Petersen, P.J., Ruzin, A.V., Tuckman, M., Sutherland, A.G.
Deposit date:2004-01-07
Release date:2005-01-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction
BIOORG.MED.CHEM.LETT., 14, 2004
1VND
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VND/NK-2 PROTEIN (HOMEODOMAIN), NMR
Descriptor:VND/NK-2 PROTEIN
Authors:Tsao, D.H.H., Gruschus, J.M., Wang, L.-H., Nirenberg, M., Ferretti, J.A.
Deposit date:1996-05-22
Release date:1996-11-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The three-dimensional solution structure of the NK-2 homeodomain from Drosophila.
J.Mol.Biol., 251, 1995
1F2H
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SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF THE TNFR1 ASSOCIATED PROTEIN, TRADD.
Descriptor:TUMOR NECROSIS FACTOR RECEPTOR TYPE 1 ASSOCIATED DEATH DOMAIN PROTEIN
Authors:Tsao, D., McDonaugh, T., Malakian, K., Xu, G.-Y., Telliez, J.-B., Hsu, H., Lin, L.-L.
Deposit date:2000-05-24
Release date:2001-05-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of N-TRADD and characterization of the interaction of N-TRADD and C-TRAF2, a key step in the TNFR1 signaling pathway.
Mol.Cell, 5, 2000
1NK2
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VND/NK-2 HOMEODOMAIN/DNA COMPLEX, NMR, 20 STRUCTURES
Descriptor:DNA (5'-D(*TP*GP*TP*GP*TP*CP*AP*AP*GP*TP*GP*GP*CP*TP*GP*T)-3'), DNA (5'-D(*AP*CP*AP*GP*CP*CP*AP*CP*TP*TP*GP*AP*CP*AP*CP*A)-3'), HOMEOBOX PROTEIN VND
Authors:Gruschus, J.M., Tsao, D.H.H., Wang, L.-H., Nirenberg, M., Ferretti, J.A.
Deposit date:1998-05-06
Release date:1999-02-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity.
Biochemistry, 36, 1997
1NK3
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VND/NK-2 HOMEODOMAIN/DNA COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*TP*GP*TP*GP*TP*CP*AP*AP*GP*TP*GP*GP*CP*TP*GP*T)-3'), DNA (5'-D(*AP*CP*AP*GP*CP*CP*AP*CP*TP*TP*GP*AP*CP*AP*CP*A)-3'), HOMEOBOX PROTEIN VND
Authors:Gruschus, J.M., Tsao, D.H.H., Wang, L.-H., Nirenberg, M., Ferretti, J.A.
Deposit date:1998-05-06
Release date:1998-12-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity.
Biochemistry, 36, 1997
2K2G
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SOLUTION STRUCTURE OF THE WILD-TYPE CATALYTIC DOMAIN OF HUMAN MATRIX METALLOPROTEINASE 12 (MMP-12) IN COMPLEX WITH A TIGHT-BINDING INHIBITOR
Descriptor:Macrophage metalloelastase, ZINC ION, N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine
Authors:Markus, M.A., Dwyer, B., Wolfrom, S., Li, J., Li, W., Malakian, K., Wilhelm, J., Tsao, D.H.H.
Deposit date:2008-04-01
Release date:2008-05-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of wild-type human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor.
J.Biomol.Nmr, 41, 2008
2KDY
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NMR STRUCTURE OF LP2086-B01
Descriptor:Factor H binding protein variant B01_001
Authors:Mascioni, A., Bentley, B.E., Camarda, R., Dilts, D.A., Fink, P., Gusarova, V., Hoiseth, S., Jacob, J., Lin, S.L., Malakian, K., McNeil, L.K., Mininni, T., Moy, F., Murphy, E., Novikova, E., Sigethy, S., Wen, Y., Zlotnick, G.W., Tsao, D.H.H.
Deposit date:2009-01-20
Release date:2009-02-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Basis for the Immunogenic Properties of the Meningococcal Vaccine Candidate LP2086.
J.Biol.Chem., 284, 2009
3KXZ
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THE COMPLEX CRYSTAL STRUCTURE OF LCK WITH A PROBE MOLECULE W259
Descriptor:Proto-oncogene tyrosine-protein kinase LCK, SULFATE ION, CALCIUM ION, ...
Authors:Xu, Z.B., Moy, F.J., Kelleher, K., Mosyak, L., Protein Structure Factory (PSF)
Deposit date:2009-12-04
Release date:2010-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Novel synthesis and structural characterization of a high-affinity paramagnetic kinase probe for the identification of non-ATP site binders by nuclear magnetic resonance.
J.Med.Chem., 53, 2010