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2W58
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BU of 2w58 by Molmil
Crystal Structure of the DnaI
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Tsai, K.L, Lo, Y.H, Sun, Y.J, Hsiao, C.D.
Deposit date:2008-12-08
Release date:2009-12-22
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Interplay between the Replicative Helicase Dnac and its Loader Protein Dnai from Geobacillus Kaustophilus.
J.Mol.Biol., 393, 2009
2VYF
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BU of 2vyf by Molmil
Crystal Structure of the DnaC
Descriptor: GOLD ION, REPLICATIVE DNA HELICASE
Authors:Lo, Y.H, Tsai, K.L, Sun, Y.J, Hsiao, C.D.
Deposit date:2008-07-23
Release date:2008-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The Crystal Structure of a Replicative Hexameric Helicase Dnac and its Complex with Single-Stranded DNA.
Nucleic Acids Res., 37, 2009
2VYE
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BU of 2vye by Molmil
Crystal Structure of the DnaC-ssDNA complex
Descriptor: 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP)-3', REPLICATIVE DNA HELICASE
Authors:Lo, Y.H, Tsai, K.L, Sun, Y.J, Hsiao, C.D.
Deposit date:2008-07-23
Release date:2008-12-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:The Crystal Structure of a Replicative Hexameric Helicase Dnac and its Complex with Single-Stranded DNA.
Nucleic Acids Res., 37, 2009
6XI8
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BU of 6xi8 by Molmil
Yeast TFIIK (Kin28/Ccl1/Tfb3) Complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Cyclin CCL1, ...
Authors:van Eeuwen, T, Murakami, K, Li, T, Tsai, K.L.
Deposit date:2020-06-19
Release date:2021-04-28
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structure of TFIIK for phosphorylation of CTD of RNA polymerase II.
Sci Adv, 7, 2021
3RJ1
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BU of 3rj1 by Molmil
Architecture of the Mediator Head module
Descriptor: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ...
Authors:Imasaki, T, Calero, G, Cai, G, Tsai, K.L, Yamada, K, Cardelli, F, Erdjument-Bromage, H, Tempst, P, Berger, I, Kornberg, G.L, Asturias, F.J, Kornberg, R.D, Takagi, Y.
Deposit date:2011-04-14
Release date:2011-07-27
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Architecture of the Mediator head module.
Nature, 475, 2011
7KPW
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BU of 7kpw by Molmil
Structure of the H-lobe of yeast CKM
Descriptor: Mediator of RNA polymerase II transcription subunit 12
Authors:Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L.
Deposit date:2020-11-12
Release date:2021-01-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module.
Sci Adv, 7, 2021
7KPV
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BU of 7kpv by Molmil
Structure of kinase and Central lobes of yeast CKM
Descriptor: Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ...
Authors:Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L.
Deposit date:2020-11-12
Release date:2021-01-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module.
Sci Adv, 7, 2021
7KPX
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BU of 7kpx by Molmil
Structure of the yeast CKM
Descriptor: Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ...
Authors:Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L.
Deposit date:2020-11-12
Release date:2021-01-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module.
Sci Adv, 7, 2021
7KUE
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BU of 7kue by Molmil
CryoEM structure of Yeast TFIIK (Kin28/Ccl1/Tfb3) Complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Cyclin CCL1, ...
Authors:van Eeuwen, T, Murakami, K, Li, T, Tsai, K.L.
Deposit date:2020-11-24
Release date:2021-04-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of TFIIK for phosphorylation of CTD of RNA polymerase II.
Sci Adv, 7, 2021
6AUI
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BU of 6aui by Molmil
Human ribonucleotide reductase large subunit (alpha) with dATP and CDP
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Brignole, E.J, Drennan, C.L, Asturias, F.J, Tsai, K.L, Penczek, P.A.
Deposit date:2017-09-01
Release date:2018-04-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:3.3- angstrom resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound.
Elife, 7, 2018
7UIG
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BU of 7uig by Molmil
Mediator-PIC Early (Mediator A)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-29
Release date:2023-02-15
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIL
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BU of 7uil by Molmil
Mediator-PIC Early (Tail A/B Dimer)
Descriptor: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 15, ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-29
Release date:2023-02-15
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIC
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BU of 7uic by Molmil
Mediator-PIC Early (Tail A)
Descriptor: Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 15, Mediator of RNA polymerase II transcription subunit 16, ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-29
Release date:2023-02-15
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UI9
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BU of 7ui9 by Molmil
Core Mediator-PICearly (Copy A)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-28
Release date:2023-02-15
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIF
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BU of 7uif by Molmil
Mediator-PIC Early (Core B)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-29
Release date:2023-02-15
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIK
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BU of 7uik by Molmil
Mediator-PIC Early (Tail A + Upstream DNA & Activator)
Descriptor: DNA (37-MER), DNA (38-MER), Mediator of RNA polymerase II transcription subunit 14, ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-29
Release date:2023-03-01
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIO
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BU of 7uio by Molmil
Mediator-PIC Early (Composite Model)
Descriptor: ALANINE, ASPARTIC ACID, DNA (37-MER), ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-29
Release date:2023-03-01
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
5U0S
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BU of 5u0s by Molmil
Cryo-EM structure of the Mediator-RNAPII complex
Descriptor: Mediator complex subunit 10, Mediator complex subunit 11, Mediator complex subunit 14, ...
Authors:Tsai, K.-L, Yu, X, Gopalan, S, Chao, T.-C, Zhang, Y, Florens, L, Washburn, M.P, Murakami, K, Conaway, R.C, Conaway, J.W, Asturias, F.
Deposit date:2016-11-26
Release date:2017-03-08
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Mediator structure and rearrangements required for holoenzyme formation.
Nature, 544, 2017
5U0P
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BU of 5u0p by Molmil
Cryo-EM structure of the transcriptional Mediator
Descriptor: Mediator complex subunit 10, Mediator complex subunit 11, Mediator complex subunit 14, ...
Authors:Tsai, K.-L, Yu, X, Gopalan, S, Chao, T.-C, Zhang, Y, Florens, L, Washburn, M.P, Murakami, K, Conaway, R.C, Conaway, J.W, Asturias, F.
Deposit date:2016-11-26
Release date:2017-03-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Mediator structure and rearrangements required for holoenzyme formation.
Nature, 544, 2017
4QCC
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BU of 4qcc by Molmil
Structure of a cube-shaped, highly porous protein cage designed by fusing symmetric oligomeric domains
Descriptor: 2-dehydro-3-deoxy-6-phosphogalactonate aldolase, peptidyl-prolyl cis-trans isomerase chimera
Authors:Lai, Y.-T, Yeates, T.O.
Deposit date:2014-05-10
Release date:2014-11-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (7.078 Å)
Cite:Structure of a designed protein cage that self-assembles into a highly porous cube.
Nat Chem, 6, 2014
4IQ4
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BU of 4iq4 by Molmil
Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P21212 form
Descriptor: Non-haem bromoperoxidase BPO-A2, Matrix protein 1
Authors:Lai, Y.-T, Sawaya, M.R, Yeates, T.O.
Deposit date:2013-01-10
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.495 Å)
Cite:Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly.
J.Am.Chem.Soc., 135, 2013
4ITV
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BU of 4itv by Molmil
Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P212121 form
Descriptor: Non-haem bromoperoxidase BPO-A2, Matrix protein 1
Authors:Lai, Y.-T, Sawaya, M.R, Yeates, T.O.
Deposit date:2013-01-18
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.598 Å)
Cite:Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly.
J.Am.Chem.Soc., 135, 2013
4IVJ
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BU of 4ivj by Molmil
Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, I222 form
Descriptor: Non-haem bromoperoxidase BPO-A2, Matrix protein 1
Authors:Lai, Y.-T, Sawaya, M.R, Yeates, T.O.
Deposit date:2013-01-23
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (7.351 Å)
Cite:Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly.
J.Am.Chem.Soc., 135, 2013

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