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3KGU
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BU of 3kgu by Molmil
Wild type human transthyretin (TTR) complexed with genistein (TTRwt:GEN) pH 7.5
Descriptor: GENISTEIN, Transthyretin
Authors:Trivella, D.B, Polikarpov, I.
Deposit date:2009-10-29
Release date:2010-03-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J.Struct.Biol., 170, 2010
3KGT
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BU of 3kgt by Molmil
V30M mutant human transthyretin (TTR) complexed with genistein (V30M:GEN) pH 7.5
Descriptor: GENISTEIN, Transthyretin
Authors:Trivella, D.B, Polikarpov, I.
Deposit date:2009-10-29
Release date:2010-03-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J.Struct.Biol., 170, 2010
3KGS
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BU of 3kgs by Molmil
V30M mutant human transthyretin (TTR) (apoV30M) pH 7.5
Descriptor: Transthyretin
Authors:Trivella, D.B, Polikarpov, I.
Deposit date:2009-10-29
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J.Struct.Biol., 170, 2010
4WIF
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BU of 4wif by Molmil
Crystal structure of E47Q mutant cytidine deaminase from Mycobacterium tuberculosis (MtCDA E47Q)
Descriptor: Cytidine deaminase, ZINC ION
Authors:Trivella, D.B, Sanchez-Quitian, A.Z, Basso, L.A, Santos, D.S.
Deposit date:2014-09-25
Release date:2015-09-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of E47Q mutant cytidine deaminase from Mycobacterium tuberculosis (MtCDA E47Q)
Rsc Adv, 2015
4LTC
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BU of 4ltc by Molmil
Crystal structure of yeast 20S proteasome in complex with enone carmaphycin analogue 6
Descriptor: N-hexanoyl-L-valyl-N~1~-[(4S,5S,6R)-5-hydroxy-2,6-dimethyloctan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, ...
Authors:Stein, M, Trivella, D.B.B, Groll, M.
Deposit date:2013-07-23
Release date:2014-07-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
3NEE
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BU of 3nee by Molmil
Wild type human transthyretin (TTR) complexed with GC-1 (TTRwt:GC-1)
Descriptor: GLYCEROL, Transthyretin, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
Authors:Trivella, D.B.B, Polikarpov, I.
Deposit date:2010-06-08
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
J.Struct.Biol., 173, 2011
3NES
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BU of 3nes by Molmil
V30M mutant human transthyretin (TTR) complexed with GC-1 (V30M:GC-1)
Descriptor: GLYCEROL, Transthyretin, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
Authors:Trivella, D.B.B, Polikarpov, I.
Deposit date:2010-06-09
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
J.Struct.Biol., 173, 2011
3NEO
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BU of 3neo by Molmil
Wild type human transthyretin (TTR) complexed with GC-24 (TTRwt:GC-24)
Descriptor: Transthyretin, [4-(3-BENZYL-4-HYDROXYBENZYL)-3,5-DIMETHYLPHENOXY]ACETIC ACID
Authors:Trivella, D.B.B, Polikarpov, I.
Deposit date:2010-06-09
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
J.Struct.Biol., 173, 2011
3NEX
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BU of 3nex by Molmil
V30M mutant human transthyretin (TTR) complexed with GC-24 (V30M:GC-24)
Descriptor: GLYCEROL, Transthyretin, [4-(3-BENZYL-4-HYDROXYBENZYL)-3,5-DIMETHYLPHENOXY]ACETIC ACID
Authors:Trivella, D.B.B, Polikarpov, I.
Deposit date:2010-06-09
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
J.Struct.Biol., 173, 2011
4HNP
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BU of 4hnp by Molmil
Crystal structure of yeast 20S proteasome in complex with vinylketone carmaphycin analogue VNK1
Descriptor: N-hexanoyl-L-valyl-N~1~-[(3S,4S)-3-hydroxy-2,6-dimethylhept-1-en-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, N-hexanoyl-L-valyl-N~1~-[(3S,4S)-3-hydroxy-2,6-dimethylheptan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Proteasome component C1, ...
Authors:Trivella, D.B.B, Stein, M, Groll, M.
Deposit date:2012-10-20
Release date:2014-01-29
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
4HRC
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BU of 4hrc by Molmil
Crystal structure of yeast 20S proteasome in complex with epoxyketone carmaphycin analogue 3
Descriptor: N-hexanoyl-L-valyl-N~1~-[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Proteasome component C1, Proteasome component C11, ...
Authors:Trivella, D.B.B, Stein, M, Groll, M.
Deposit date:2012-10-27
Release date:2014-01-29
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
4HRD
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BU of 4hrd by Molmil
Crystal structure of yeast 20S proteasome in complex with the natural product carmaphycin A
Descriptor: N-[(2S)-1-({(2S)-1-{[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]amino}-4-[(R)-methylsulfinyl]-1-oxobutan-2-yl}amino)-3-methyl-1-oxobutan-2-yl]hexanamide, Proteasome component C1, Proteasome component C11, ...
Authors:Trivella, D.B.B, Stein, M, Groll, M.
Deposit date:2012-10-27
Release date:2014-01-29
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
4DEU
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BU of 4deu by Molmil
Crystal Structure of the Wild Type TTR Binding Naringenin (TTRwt:NAR)
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, NARINGENIN, ...
Authors:Trivella, D.B.B, Polikarpov, I.
Deposit date:2012-01-22
Release date:2012-11-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180, 2012
4DES
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BU of 4des by Molmil
Crystal Structure of the Wild Type TTR Binding Chrysin (TTRwt:CHR)
Descriptor: Transthyretin, chrysin
Authors:Trivella, D.B.B, Polikarpov, I.
Deposit date:2012-01-21
Release date:2012-11-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180, 2012
4DET
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BU of 4det by Molmil
Crystal Structure of the Wild Type TTR Binding Kaempferol (TTRwt:KAE)
Descriptor: 3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE, Transthyretin
Authors:Trivella, D.B.B, Polikarpov, I.
Deposit date:2012-01-22
Release date:2012-11-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180, 2012
4DEW
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BU of 4dew by Molmil
Crystal Structure of the Wild Type TTR Binding Luteolin (TTRwt:LUT)
Descriptor: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, Transthyretin
Authors:Trivella, D.B.B, Polikarpov, I.
Deposit date:2012-01-22
Release date:2012-11-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180, 2012
4DER
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BU of 4der by Molmil
Crystal Structure of the Wild Type TTR Binding Apigenin (TTRwt:API)
Descriptor: 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, GLYCEROL, Transthyretin
Authors:Trivella, D.B.B, Polikarpov, I.
Deposit date:2012-01-21
Release date:2012-11-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180, 2012
3TKM
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BU of 3tkm by Molmil
Crystal structure PPAR delta binding GW0742
Descriptor: GLYCEROL, Peroxisome proliferator-activated receptor delta, {4-[({2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid
Authors:Trivella, D.B.B, Batista, F.H, Polikarpov, I.
Deposit date:2011-08-27
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.953 Å)
Cite:Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding.
Plos One, 7, 2012
4Z9B
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BU of 4z9b by Molmil
Crystal structure of Low Molecular Weight Protein Tyrosine Phosphatase isoform A complexed with benzylphosphonic acid
Descriptor: Low molecular weight phosphotyrosine protein phosphatase, benzylphosphonic acid
Authors:Fonseca, E.M.B, Trivella, D.B.B, Scorsato, V, Dias, M.P, de Oliveira, F.L, Miranda, P.C.M.L, Aparicio, R.
Deposit date:2015-04-10
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates.
Bioorg.Med.Chem., 23, 2015
4Z9A
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BU of 4z9a by Molmil
Crystal structure of Low Molecular Weight Protein Tyrosine Phosphatase isoform A complexed with phenylmethanesulfonic acid
Descriptor: GLYCEROL, Low molecular weight phosphotyrosine protein phosphatase, SULFATE ION, ...
Authors:Trivella, D.B.B, Fonseca, E.M.B, Scorsato, V, Dias, M.P, Aparicio, R.
Deposit date:2015-04-10
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates.
Bioorg.Med.Chem., 23, 2015
4Z99
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BU of 4z99 by Molmil
Crystal structure of the apo Low Molecular Weight Protein Tyrosine Phosphatase isoform A
Descriptor: Low molecular weight phosphotyrosine protein phosphatase
Authors:Fonseca, E.M.B, Scorsato, V, Dias, M.P, de Oliveria, F.L, Miranda, P.C.M.L, Aparicio, R.
Deposit date:2015-04-10
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates.
Bioorg.Med.Chem., 23, 2015

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PDB entries from 2024-03-27

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