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4A56
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BU of 4a56 by Molmil
Crystal structure of the type 2 secretion system pilotin from Klebsiella Oxytoca
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, PULLULANASE SECRETION PROTEIN PULS
Authors:Tosi, T, Nickerson, N.N, Mollica, L, RingkjobingJensen, M, Blackledge, M, Baron, B, England, P, Pugsley, A.P, Dessen, A.
Deposit date:2011-10-24
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Pilotin-Secretin Recognition in the Type II Secretion System of Klebsiella Oxytoca.
Mol.Microbiol, 82, 2011
6HUW
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BU of 6huw by Molmil
Crystal structure of CdaA from Bacillus subtilis
Descriptor: Diadenylate cyclase
Authors:Tosi, T, Freemont, P.S, Grundling, A.
Deposit date:2018-10-09
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:CdaA/GlmM complex in Bacillus subtilis
To Be Published
2WCQ
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BU of 2wcq by Molmil
Crystal Structure of Tip-Alpha N34 (HP0596) from Helicobacter pylori at pH4
Descriptor: CITRIC ACID, TNF-ALPHA INDUCER PROTEIN
Authors:Tosi, T, Cioci, G, Jouravleva, K, Dian, C, Terradot, L.
Deposit date:2009-03-13
Release date:2009-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of the Tumor Necrosis Factor Alpha Inducing Protein Tipalpha: A Novel Virulence Factor from Helicobacter Pylori.
FEBS Lett., 583, 2009
2WCR
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BU of 2wcr by Molmil
Crystal Structure of Tip-Alpha N34 (HP0596) from Helicobacter pylori at pH8
Descriptor: IMIDAZOLE, NICKEL (II) ION, TNF-ALPHA INDUCER PROTEIN
Authors:Tosi, T, Cioci, G, Jouravleva, K, Dian, C, Terradot, L.
Deposit date:2009-03-13
Release date:2009-05-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of the Tumor Necrosis Factor Alpha Inducing Protein Tipalpha: A Novel Virulence Factor from Helicobacter Pylori.
FEBS Lett., 583, 2009
6GYZ
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BU of 6gyz by Molmil
Crystal structure of GlmM from Staphylococcus aureus
Descriptor: Phosphoglucosamine mutase
Authors:Tosi, T, Freemont, P.S, Grundling, A.
Deposit date:2018-07-02
Release date:2019-01-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM.
PLoS Pathog., 15, 2019
6GYW
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BU of 6gyw by Molmil
Crystal structure of DacA from Staphylococcus aureus
Descriptor: Diadenylate cyclase
Authors:Tosi, T, Freemont, P.S, Grundling, A.
Deposit date:2018-07-02
Release date:2019-01-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM.
PLoS Pathog., 15, 2019
6GYY
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BU of 6gyy by Molmil
Crystal structure of DacA from Staphylococcus aureus, N166C/T172C double mutant
Descriptor: Diadenylate cyclase
Authors:Tosi, T, Freemont, P.S, Grundling, A.
Deposit date:2018-07-02
Release date:2019-01-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM.
PLoS Pathog., 15, 2019
6GYX
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BU of 6gyx by Molmil
Crystal structure of DacA from Staphylococcus aureus in complex with ApCpp
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, Diadenylate cyclase, MANGANESE (II) ION
Authors:Tosi, T, Freemont, P.S, Grundling, A.
Deposit date:2018-07-02
Release date:2019-01-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM.
PLoS Pathog., 15, 2019
5IIP
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BU of 5iip by Molmil
Staphylococcus aureus OpuCA
Descriptor: Glycine betaine/carnitine/choline ABC transporter%2C ATP-binding protein%2C putative
Authors:Tosi, T, Campeotto, I, Freemont, P.S, Grundling, A.
Deposit date:2016-03-01
Release date:2016-08-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The second messenger c-di-AMP inhibits the osmolyte uptake system OpuC in Staphylococcus aureus.
Sci.Signal., 9, 2016
6EOW
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BU of 6eow by Molmil
Structure of Raspberry Ketone Synthase with Hydroxybenzalacetone
Descriptor: 4-(4-hydroxyphenyl)butan-2-one, Ketone/zingerone synthase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Tosi, T, Moore, S.J, Freemont, P.S.
Deposit date:2017-10-10
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A cell-free synthetic biochemistry platform for raspberry ketone production
Biorxiv, 2018
7OJS
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BU of 7ojs by Molmil
Complex structure 2 of the Bacillus subtilis CdaA c-di-AMP cyclase domain (CdaACD) and the phosphoglucomutase GlmM short variant (GlmMF369)
Descriptor: Cyclic di-AMP synthase CdaA, Phosphoglucosamine mutase
Authors:Pathania, M, Grundling, A.G, Freemont, P.
Deposit date:2021-05-17
Release date:2021-10-27
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM.
J.Biol.Chem., 297, 2021
7OJR
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BU of 7ojr by Molmil
Bacillus subtilis phosphoglucomutase GlmM (phosphate bound)
Descriptor: PHOSPHATE ION, Phosphoglucosamine mutase
Authors:Pathania, M, Grundling, A.G, Freemont, P.
Deposit date:2021-05-17
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM.
J.Biol.Chem., 297, 2021
7OLH
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BU of 7olh by Molmil
Bacillus subtilis Complex structure 1 of diadenylate cyclase CdaA cytoplasmic domain (CdaACD) and the phosphoglucomutase GlmM short variant (GlmMF369)
Descriptor: Cyclic di-AMP synthase CdaA, Phosphoglucosamine mutase
Authors:Pathania, M, Grundling, A.G, Freemont, P.
Deposit date:2021-05-20
Release date:2021-10-27
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM.
J.Biol.Chem., 297, 2021
7OML
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BU of 7oml by Molmil
Bacillus subtilis phosphoglucomutase GlmM (metal bound)
Descriptor: MAGNESIUM ION, Phosphoglucosamine mutase
Authors:Pathania, M, Grundling, A.G, Freemont, P.
Deposit date:2021-05-24
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM.
J.Biol.Chem., 297, 2021
4G0H
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BU of 4g0h by Molmil
Crystal structure of the N-terminal domain of Helicobacter pylori CagA protein
Descriptor: Cytotoxicity-associated immunodominant antigen
Authors:Kaplan-Turkoz, B, Remaut, H, Dian, C, Louche, A, Terradot, L.
Deposit date:2012-07-09
Release date:2012-08-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural insights into Helicobacter pylori oncoprotein CagA interaction with beta 1 integrin.
Proc.Natl.Acad.Sci.USA, 109, 2012

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