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5MXX
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BU of 5mxx by Molmil
Crystal structure of human SR protein kinase 1 (SRPK1) in complex with compound 1
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-methyl-~{N}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide, ...
Authors:Tallant, C, Redondo, C, Batson, J, Toop, H.D, Babaebi-Jadidib, R, Savitsky, P, Elkins, J.M, Newman, J.A, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bates, D.O, Morris, J.C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2017-01-25
Release date:2017-05-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.
ACS Chem. Biol., 12, 2017
5MY8
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BU of 5my8 by Molmil
Crystal structure of SRPK1 in complex with SPHINX31
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, DIMETHYL SULFOXIDE, ...
Authors:Chaikuad, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2017-01-25
Release date:2017-05-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.
ACS Chem. Biol., 12, 2017
5MYV
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BU of 5myv by Molmil
Crystal structure of SRPK2 in complex with compound 1
Descriptor: 5-methyl-~{N}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide, DIMETHYL SULFOXIDE, SRSF protein kinase 2,SRSF protein kinase 2, ...
Authors:Chaikuad, A, Pike, A.C.W, Savitsky, P, von Delft, F, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2017-01-29
Release date:2017-05-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.
ACS Chem. Biol., 12, 2017

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PDB entries from 2024-03-27

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