Author results

5WT9
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COMPLEX STRUCTURE OF PD-1 AND NIVOLUMAB-FAB
分子名称:Heavy Chain of Nivolumab, Light Chain of Nivolumab, Programmed cell death protein 1, ...
著者Tan, S., Zhang, H., Chai, Y., Song, H., Tong, Z., Wang, Q., Qi, J., Wong, G., Zhu, X., Liu, W.J., Gao, S., Wang, Z., Shi, Y., Yang, F., Gao, G.F., Yan, J.
登録日2016-12-10
公開日2017-02-15
最終更新日2017-12-13
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献An unexpected N-terminal loop in PD-1 dominates binding by nivolumab.
Nat Commun, 8, 2017
2FLR
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NOVEL 5-AZAINDOLE FACTOR VIIA INHIBITORS
分子名称:Coagulation factor VII, Tissue factor, [2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA
著者Riggs, J.R., Hu, H., Kolesnikov, A., Tong, Z., Leahy, E.M., Wesson, K.E., Shrader, W.D., Vijaykumar, D., Wahl, T.A., Sprengeler, P.A., Green, M.J., Yu, C., Katz, B.A., Young, W.B.
登録日2006-01-06
公開日2007-01-23
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Novel 5-azaindole factor VIIa inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
5GZN
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
分子名称:Genome polyprotein, Antibody Heavy chain, Antibody light chain
著者Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
登録日2016-09-29
公開日2016-12-28
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
5GZO
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
分子名称:Genome polyprotein, Antibody heavy chain, Antibody light chain
著者Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
登録日2016-09-29
公開日2017-01-18
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (2.755 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
5XJ3
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COMPLEX STRUCTURE OF IPILIMUMAB-SCFV AND CTLA-4
分子名称:ipilimumab-VH, ipilimumab-VL, Cytotoxic T-lymphocyte protein 4
著者He, M., Chai, Y., Qi, J., Tong, Z., Tan, S., Gao, G.F.
登録日2017-04-29
公開日2018-04-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies
Oncotarget, 8, 2017
6IEA
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STRUCTURE OF RVFV GN AND HUMAN MONOCLONAL ANTIBODY R13
分子名称:NSmGnGc, R13 L chain, R13 H chain, ...
著者Wang, Q.H., Wu, Y., Gao, F., Qi, J.X., Gao, G.F.
登録日2018-09-13
公開日2019-04-10
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
6IEB
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STRUCTURE OF RVFV GN AND HUMAN MONOCLONAL ANTIBODY R15
分子名称:R15 H chain, R15 L chain, NSmGnGc
著者Wang, Q.H., Wu, Y., Gao, F., Qi, J.X., Gao, G.F.
登録日2018-09-13
公開日2019-04-10
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (2.409 Å)
主引用文献Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
6IEC
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STRUCTURE OF RVFV GN AND HUMAN MONOCLONAL ANTIBODY R17
分子名称:NSmGnGc, R17 H chain, R17 L chain
著者Wang, Q.H., Wu, Y., Gao, F., Qi, J.X., Gao, G.F.
登録日2018-09-13
公開日2019-04-10
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
6IEK
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STRUCTURE OF RVFV GN AND HUMAN MONOCLONAL ANTIBODY R12
分子名称:NSmGnGc, Heavy chain of Fab R12, Light chain of Fab R12
著者Wang, Q.H., Wu, Y., Gao, F., Qi, J.X., Gao, G.F.
登録日2018-09-14
公開日2019-04-10
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
6A3V
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COMPLEX STRUCTURE OF HUMAN 4-1BB AND 4-1BBL
分子名称:Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9, N-ACETYL-D-GLUCOSAMINE
著者Li, Y., Zhang, C., Chai, Y., Qi, J., Tien, P., Gao, S., Gao, G.F.
登録日2018-06-17
公開日2018-10-10
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (3.391 Å)
主引用文献Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.
Cell Rep, 25, 2018
6A3W
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COMPLEX STRUCTURE OF 4-1BB AND UTOMILUMAB
分子名称:utomilumab VH, utomilumab VL, Tumor necrosis factor receptor superfamily member 9, ...
著者Li, Y., Tan, S., Zhang, C., Chai, Y., Qi, J., Tien, P., Gao, S., Gao, G.F.
登録日2018-06-17
公開日2018-10-10
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.
Cell Rep, 25, 2018
4PL0
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CRYSTAL STRUCTURE OF THE ANTIBACTERIAL PEPTIDE ABC TRANSPORTER MCJD IN AN OUTWARD OCCLUDED STATE
分子名称:Microcin-J25 export ATP-binding/permease protein McjD, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
著者Choudhury, H.G., Beis, K.
登録日2014-05-15
公開日2014-06-18
最終更新日2014-06-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of an antibacterial peptide ATP-binding cassette transporter in a novel outward occluded state.
Proc.Natl.Acad.Sci.USA, 111, 2014
5GZR
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ZIKA VIRUS E PROTEIN COMPLEXED WITH A NEUTRALIZING ANTIBODY Z23-FAB
分子名称:structural protein E, strutural protein M, Z23 Fab heavy chain, ...
著者Gao, G.G., Shi, Y., Peng, R., Liu, S.
登録日2016-10-01
公開日2016-11-30
最終更新日2016-12-28
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
1FW1
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GLUTATHIONE TRANSFERASE ZETA/MALEYLACETOACETATE ISOMERASE
分子名称:GLUTATHIONE TRANSFERASE ZETA, SULFATE ION, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ...
著者Polekhina, G., Board, P.G., Blackburn, A.C., Parker, M.W.
登録日2000-09-20
公開日2001-09-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity.
Biochemistry, 40, 2001
5EG1
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ANTIBACTERIAL PEPTIDE ABC TRANSPORTER MCJD WITH A RESOLVED LIPID
分子名称:Microcin-J25 export ATP-binding/permease protein McjD, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
著者Choudhury, H.G., Beis, K.
登録日2015-10-26
公開日2016-08-31
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Structural and Functional Basis for Lipid Synergy on the Activity of the Antibacterial Peptide ABC Transporter McjD.
J.Biol.Chem., 291, 2016
5OFP
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STRUCTURE OF THE ANTIBACTERIAL PEPTIDE ABC TRANSPORTER MCJD IN AN APO INWARD OCCLUDED CONFORMATION
分子名称:Microcin-J25 export ATP-binding/permease protein McjD
著者Beis, K., Choudhury, H.G.
登録日2017-07-11
公開日2017-09-06
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (4.71 Å)
主引用文献Structural basis for antibacterial peptide self-immunity by the bacterial ABC transporter McjD.
EMBO J., 36, 2017
5OFR
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STRUCTURE OF THE ANTIBACTERIAL PEPTIDE ABC TRANSPORTER MCJD IN A HIGH ENERGY OUTWARD OCCLUDED INTERMEDIATE STATE
分子名称:Microcin-J25 export ATP-binding/permease protein McjD, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Beis, K., Bountra, K.
登録日2017-07-11
公開日2017-09-06
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis for antibacterial peptide self-immunity by the bacterial ABC transporter McjD.
EMBO J., 36, 2017