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4BAY
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BU of 4bay by Molmil
Phosphomimetic mutant of LSD1-8a splicing variant in complex with CoREST
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1
Authors:Toffolo, E, Paganini, L, Rusconi, F, Tortorici, M, Pilotto, S, Verpelli, C, Tedeschi, G, Maffioli, E, Sala, C, Mattevi, A, Battaglioli, E.
Deposit date:2012-09-17
Release date:2013-11-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Phosphorylation of Neuronal Lysine-Specific Demethylase 1Lsd1/Kdm1A Impairs Transcriptional Repression by Regulating Interaction with Corest and Histone Deacetylases Hdac1/2.
J.Neurochem., 128, 2014
4CZZ
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BU of 4czz by Molmil
Histone demethylase LSD1(KDM1A)-CoREST3 Complex
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 3
Authors:Barrios, A.P, Gomez, A.V, Saez, J.E, Ciossani, G, Toffolo, E, Battaglioli, E, Mattevi, A, Andres, M.E.
Deposit date:2014-04-23
Release date:2014-06-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Differential Properties of Transcriptional Complexes Formed by the Corest Family.
Mol.Cell.Biol., 34, 2014
2X0L
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BU of 2x0l by Molmil
Crystal structure of a neuro-specific splicing variant of human histone lysine demethylase LSD1.
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, HISTONE H3 PEPTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
Authors:Zibetti, C, Adamo, A, Binda, C, Forneris, F, Verpelli, C, Ginelli, E, Mattevi, A, Sala, C, Battaglioli, E.
Deposit date:2009-12-15
Release date:2010-03-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Alternative Splicing of the Histone Demethylase Lsd1/Kdm1 Contributes to the Modulation of Neurite Morphogenesis in the Mammalian Nervous System.
J.Neurosci., 30, 2010
5L3D
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BU of 5l3d by Molmil
Human LSD1/CoREST: LSD1 Y761H mutation
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, REST corepressor 1
Authors:Pilotto, S, Speranzini, V, Marabelli, C, Mattevi, A.
Deposit date:2016-04-06
Release date:2016-05-04
Last modified:2016-12-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors.
Hum.Mol.Genet., 25, 2016
5L3B
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BU of 5l3b by Molmil
Human LSD1/CoREST: LSD1 D556G mutation
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, REST corepressor 1
Authors:Pilotto, S, Speranzini, V, Marabelli, C.
Deposit date:2016-04-06
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors.
Hum.Mol.Genet., 25, 2016
5L3C
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BU of 5l3c by Molmil
Human LSD1/CoREST: LSD1 E379K mutation
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, REST corepressor 1
Authors:Pilotto, S, Speranzini, V, Marabelli, C, Mattevi, A.
Deposit date:2016-04-06
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors.
Hum.Mol.Genet., 25, 2016

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PDB entries from 2024-03-27

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