Author results

1TLE
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LE (LAMININ-TYPE EGF-LIKE) MODULE GIII4 IN SOLUTION AT PH 3.5 AND 290 K, NMR, 14 STRUCTURES
Descriptor:LAMININ
Authors:Baumgartner, R., Czisch, M., Mayer, U., Schl, E.P., Huber, R., Timpl, R., Holak, T.A.
Deposit date:1996-01-26
Release date:1997-02-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the nidogen binding LE module of the laminin gamma1 chain in solution.
J.Mol.Biol., 257, 1996
1KLO
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CRYSTAL STRUCTURE OF THREE CONSECUTIVE LAMININ-TYPE EPIDERMAL GROWTH FACTOR-LIKE (LE) MODULES OF LAMININ GAMMA1 CHAIN HARBORING THE NIDOGEN BINDING SITE
Descriptor:LAMININ
Authors:Stetefeld, J., Mayer, U., Timpl, R., Huber, R.
Deposit date:1996-02-02
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of three consecutive laminin-type epidermal growth factor-like (LE) modules of laminin gamma1 chain harboring the nidogen binding site.
J.Mol.Biol., 257, 1996
1BMO
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BM-40, FS/EC DOMAIN PAIR
Descriptor:BM-40, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
Authors:Hohenester, E., Maurer, P., Timpl, R.
Deposit date:1997-03-25
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of a pair of follistatin-like and EF-hand calcium-binding domains in BM-40.
EMBO J., 16, 1997
1GL4
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NIDOGEN-1 G2/PERLECAN IG3 COMPLEX
Descriptor:NIDOGEN-1, BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN, ZINC ION, ...
Authors:Kvansakul, M., Hopf, M., Ries, A., Timpl, R., Hohenester, E.
Deposit date:2001-08-23
Release date:2001-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the High-Affinity Interaction of Nidogen-1 with Immunoglobulin-Like Domain 3 of Perlecan
Embo J., 20, 2001
1OKQ
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LAMININ ALPHA 2 CHAIN LG4-5 DOMAIN PAIR, CA1 SITE MUTANT
Descriptor:LAMININ ALPHA 2 CHAIN, CALCIUM ION
Authors:Wizemann, H., Garbe, J.H.O., Friedrich, M.V.K., Timpl, R., Sasaki, T., Hohenester, E.
Deposit date:2003-07-28
Release date:2003-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Distinct Requirements for Heparin and Alpha-Dystroglycan Binding Revealed by Structure-Based Mutagenesis of the Laminin Alpha2 Lg4-Lg5 Domain Pair
J.Mol.Biol., 332, 2003
1H4U
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DOMAIN G2 OF MOUSE NIDOGEN-1
Descriptor:NIDOGEN-1
Authors:Hopf, M., Gohring, W., Ries, A., Timpl, R., Hohenester, E.
Deposit date:2001-05-14
Release date:2001-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure and Mutational Analysis of a Perlecan-Binding Fragment of Nidogen-1
Nat.Struct.Biol., 8, 2001
1BY2
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STRUCTURE OF M2BP SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN
Descriptor:MAC-2 BINDING PROTEIN, N-ACETYL-D-GLUCOSAMINE
Authors:Hohenester, E., Sasaki, T., Timpl, R.
Deposit date:1998-10-23
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a scavenger receptor cysteine-rich domain sheds light on an ancient superfamily.
Nat.Struct.Biol., 6, 1999
1DY0
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MURINE ENDOSTATIN, CRYSTAL FORM II
Descriptor:COLLAGEN ALPHA1(XVIII) CHAIN, ZINC ION
Authors:Hohenester, E., Sasaki, T., Timpl, R.
Deposit date:2000-01-21
Release date:2000-04-11
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Variable Zinc Coordination in Endostatin
J.Mol.Biol., 297, 2000
1DY1
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MURINE ENDOSTATIN, CRYSTAL FORM III
Descriptor:COLLAGEN ALPHA1(XVIII) CHAIN, ZINC ION
Authors:Hohenester, E., Sasaki, T., Timpl, R.
Deposit date:2000-01-21
Release date:2001-01-21
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Variable Zinc Coordination in Endostatin
J.Mol.Biol., 297, 2000
1DY2
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MURINE COLLAGEN ALPHA1(XV), ENDOSTATIN DOMAIN
Descriptor:COLLAGEN ALPHA1(XV) CHAIN, SULFATE ION
Authors:Tisi, D., Hohenester, E., Sasaki, T., Timpl, R.
Deposit date:2000-01-21
Release date:2001-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Endostatin Derived from Collagens Xv and Xviii Differ in Structural and Binding Properties, Tissue Distribution and Anti-Angiogenic Activity
J.Mol.Biol., 301, 2000
1NUB
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HELIX C DELETION MUTANT OF BM-40 FS-EC DOMAIN PAIR
Descriptor:BASEMENT MEMBRANE PROTEIN BM-40, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
Authors:Hohenester, E., Sasaki, T., Timpl, R.
Deposit date:1997-12-05
Release date:1998-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectin.
EMBO J., 17, 1998
1QU0
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CRYSTAL STRUCTURE OF THE FIFTH LAMININ G-LIKE MODULE OF THE MOUSE LAMININ ALPHA2 CHAIN
Descriptor:LAMININ ALPHA2 CHAIN, CALCIUM ION, SULFATE ION
Authors:Hohenester, E., Tisi, D., Talts, J.F., Timpl, R.
Deposit date:1999-07-05
Release date:1999-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The crystal structure of a laminin G-like module reveals the molecular basis of alpha-dystroglycan binding to laminins, perlecan, and agrin.
Mol.Cell, 4, 1999
1SRA
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STRUCTURE OF A NOVEL EXTRACELLULAR CA2+-BINDING MODULE IN BM-40(SLASH)SPARC(SLASH)OSTEONECTIN
Descriptor:SPARC, CALCIUM ION
Authors:Hohenester, E., Maurer, P., Hohenadl, C., Timpl, R., Jansonius, J.N., Engel, J.
Deposit date:1995-08-21
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a novel extracellular Ca(2+)-binding module in BM-40.
Nat.Struct.Biol., 3, 1996
2C5D
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STRUCTURE OF A MINIMAL GAS6-AXL COMPLEX
Descriptor:GROWTH-ARREST-SPECIFIC PROTEIN 6 PRECURSOR, TYROSINE-PROTEIN KINASE RECEPTOR UFO, CALCIUM ION, ...
Authors:Sasaki, T., Knyazev, P.G., Clout, N.J., Cheburkin, Y., Goehring, W., Ullrich, A., Timpl, R., Hohenester, E.
Deposit date:2005-10-26
Release date:2005-12-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Basis for Gas6-Axl Signalling.
Embo J., 25, 2006
1BNL
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ZINC DEPENDENT DIMERS OBSERVED IN CRYSTALS OF HUMAN ENDOSTATIN
Descriptor:COLLAGEN XVIII, ZINC ION
Authors:Ding, Y.-H., Javaherian, K., Lo, K.-M., Chopra, R., Boehm, T., Lanciotti, J., Harris, B.A., Li, Y., Shapiro, R., Hohenester, E., Timpl, R., Folkman, J., Wiley, D.C.
Deposit date:1998-07-30
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Zinc-dependent dimers observed in crystals of human endostatin.
Proc.Natl.Acad.Sci.USA, 95, 1998
1LI1
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THE 1.9-A CRYSTAL STRUCTURE OF THE NONCOLLAGENOUS (NC1) DOMAIN OF HUMAN PLACENTA COLLAGEN IV SHOWS STABILIZATION VIA A NOVEL TYPE OF COVALENT MET-LYS CROSS-LINK
Descriptor:Collagen alpha 1(IV), Collagen alpha 2(IV), ACETATE ION
Authors:Than, M.E., Henrich, S., Huber, R., Ries, A., Mann, K., Kuhn, K., Timpl, R., Bourenkov, G.P., Bartunik, H.D., Bode, W.
Deposit date:2002-04-17
Release date:2002-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link.
Proc.Natl.Acad.Sci.USA, 99, 2002
1H30
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C-TERMINAL LG DOMAIN PAIR OF HUMAN GAS6
Descriptor:GROWTH-ARREST-SPECIFIC PROTEIN, CALCIUM ION, SULFATE ION
Authors:Sasaki, T., Knyazev, P.G., Cheburkin, Y., Gohring, W., Tisi, D., Ullrich, A., Timpl, R., Hohenester, E.
Deposit date:2002-08-21
Release date:2003-01-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Carboxy-Terminal Fragment of Growth-Arrest-Specific Protein Gas6: Receptor Tyrosine Kinase Activation by Laminin G-Like Domains
J.Biol.Chem., 277, 2002
1KOE
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ENDOSTATIN
Descriptor:ENDOSTATIN
Authors:Hohenester, E., Sasaki, T., Olsen, B.R., Timpl, R.
Deposit date:1998-01-22
Release date:1999-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the angiogenesis inhibitor endostatin at 1.5 A resolution.
EMBO J., 17, 1998
1DYK
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LAMININ ALPHA 2 CHAIN LG4-5 DOMAIN PAIR
Descriptor:LAMININ ALPHA 2 CHAIN, CALCIUM ION
Authors:Tisi, D., Talts, J.F., Timple, R., Hohenester, E.
Deposit date:2000-02-01
Release date:2001-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the C-Terminal Laminin G-Like Domain Pair of the Laminin Alpha 2 Chain Harbouring Binding Sites for Alpha-Dystroglycan and Heparin
Embo J., 19, 2000
2JD4
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MOUSE LAMININ ALPHA1 CHAIN, DOMAINS LG4-5
Descriptor:LAMININ SUBUNIT ALPHA-1, MAGNESIUM ION, CHLORIDE ION
Authors:Harrison, D., Hussain, S.A., Combs, A.C., Ervasti, J.M., Yurchenco, P.D., Hohenester, E.
Deposit date:2007-01-04
Release date:2007-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure and Cell Surface Anchorage Sites of Laminin {Alpha}1Lg4-5.
J.Biol.Chem., 282, 2007
2V53
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CRYSTAL STRUCTURE OF A SPARC-COLLAGEN COMPLEX
Descriptor:SPARC, COLLAGEN ALPHA-1(III) CHAIN, CALCIUM ION, ...
Authors:Hohenester, E., Sasaki, T., Giudici, C., Farndale, R.W., Bachinger, H.P.
Deposit date:2008-10-01
Release date:2008-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis of Sequence-Specific Collagen Recognition by Sparc.
Proc.Natl.Acad.Sci.USA, 105, 2008