Author results

3FAN
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CRYSTAL STRUCTURE OF CHYMOTRYPSIN-LIKE PROTEASE/PROTEINASE (3CLSP/NSP4) OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV)
Descriptor:Non-structural protein, PHOSPHATE ION
Authors:Gao, F., Peng, H., Tian, X., Lu, G., Liu, Y., Gao, G.F.
Deposit date:2008-11-17
Release date:2009-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV).
J.Mol.Biol., 392, 2009
3FAO
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CRYSTAL STRUCTURE OF S118A MUTANT 3CLSP OF PRRSV
Descriptor:Non-structural protein, PHOSPHATE ION
Authors:Gao, F., Peng, H., Tian, X., Lu, G., Liu, Y., Gao, G.F.
Deposit date:2008-11-17
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV).
J.Mol.Biol., 392, 2009
2RFT
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CRYSTAL STRUCTURE OF INFLUENZA B VIRUS HEMAGGLUTININ IN COMPLEX WITH LSTA RECEPTOR ANALOG
Descriptor:Influenza B hemagglutinin (HA), N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Wang, Q., Tian, X., Chen, X., Ma, J.
Deposit date:2007-10-01
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for receptor specificity of influenza B virus hemagglutinin.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2RFU
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CRYSTAL STRUCTURE OF INFLUENZA B VIRUS HEMAGGLUTININ IN COMPLEX WITH LSTC RECEPTOR ANALOG
Descriptor:Influenza B hemagglutinin (HA), N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Wang, Q., Tian, X., Chen, X., Ma, J.
Deposit date:2007-10-01
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for receptor specificity of influenza B virus hemagglutinin.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4JGV
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CRYSTAL STRUCTURE OF HUMAN NUR77 LIGAND-BINDING DOMAIN IN COMPLEX WITH THPN
Descriptor:Nuclear receptor subfamily 4 group A member 1, 1-(3,4,5-trihydroxyphenyl)nonan-1-one, GLYCEROL
Authors:Zhang, Q., Li, F., Li, A., Tian, X., Wan, W., Wan, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
Deposit date:2013-03-04
Release date:2013-12-18
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway.
Nat.Chem.Biol., 10, 2014
4KZI
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CRYSTAL STRUCTURE OF TR3 LBD IN COMPLEX WITH DPDO
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL, 1-(3,5-dimethoxyphenyl)decan-1-one
Authors:Li, F., Zhang, Q., Li, A., Tian, X., Cai, Q., Wang, W., Wang, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
Deposit date:2013-05-30
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling
Nat.Struct.Mol.Biol., 2013
4KZJ
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CRYSTAL STRUCTURE OF TR3 LBD L449W MUTANT
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
Authors:Li, F., Zhang, Q., Li, A., Tian, X., Cai, Q., Wang, W., Wang, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
Deposit date:2013-05-30
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling
Nat.Struct.Mol.Biol., 2013
4KZM
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CRYSTAL STRUCTURE OF TR3 LBD S553A MUTANT
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
Authors:Li, F., Zhang, Q., Li, A., Tian, X., Cai, Q., Wang, W., Wang, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
Deposit date:2013-05-30
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling
Nat.Struct.Mol.Biol., 2013
2MIU
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STRUCTURE OF FHL2 LIM ADAPTOR AND ITS INTERACTION WITH SKI
Descriptor:Four and a half LIM domains protein 2, ZINC ION
Authors:Yang, Y., Sun, Y., Medrano, E.E., Tian, X., Weiss, M.A.
Deposit date:2013-12-20
Release date:2014-01-15
Method:SOLUTION NMR
Cite:Structure of FHL2 LIM adaptor and its Interaction with Ski
To be Published
3BT6
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CRYSTAL STRUCTURE OF INFLUENZA B VIRUS HEMAGGLUTININ
Descriptor:Influenza B hemagglutinin (HA), N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Wang, Q., Cheng, F., Lu, M., Tian, X., Ma, J.
Deposit date:2007-12-27
Release date:2008-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of unliganded influenza B virus hemagglutinin.
J.Virol., 82, 2008
4RZF
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CRYSTAL STRUCTURE ANALYSIS OF THE NUR77 LIGAND BINDING DOMAIN, S441W MUTANT
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
Authors:Li, F., Tian, X., Li, A., Li, L., Liu, Y., Chen, H., Wu, Q., Lin, T.
Deposit date:2014-12-21
Release date:2015-03-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
4RZG
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CRYSTAL STRUCTURE ANALYSIS OF THE DNPA-BOUNDED NUR77 LIGAND BINDING DOMAIN
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL, pentyl (3,5-dihydroxy-2-nonanoylphenyl)acetate
Authors:Li, F., Tian, X., Li, A., Li, L., Liu, Y., Chen, H., Wu, Q., Lin, T.
Deposit date:2014-12-21
Release date:2015-03-18
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
3H6K
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CRYSTAL STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID-DEHYDROGENASE BOUND TO AN ORTHO-CHLRO-SULFONYL-PIPERAZINE INHIBITOR
Descriptor:Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-chloro-4-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl}sulfonyl)benzamide
Authors:Bard, J., Svenson, K.
Deposit date:2009-04-23
Release date:2009-12-01
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.187 Å)
Cite:Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model.
J.Med.Chem., 52, 2009
3HFG
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CRYSTAL STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID-DEHYDROGENASE BOUND TO AN SULFONYL-PIPERAZINE INHIBITOR
Descriptor:Corticosteroid 11-beta-dehydrogenase isozyme 1, (2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-{[3-(1H-1,2,4-triazol-1-yl)phenyl]sulfonyl}piperazine, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Bard, J., Svenson, K.
Deposit date:2009-05-11
Release date:2009-09-29
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model.
J.Med.Chem., 52, 2009
4JHD
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CRYSTAL STRUCTURE OF AN ACTIN DIMER IN COMPLEX WITH THE ACTIN NUCLEATOR CORDON-BLEU
Descriptor:Actin-5C, Protein cordon-bleu, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Chen, X., Ni, F., Wang, Q.
Deposit date:2013-03-04
Release date:2013-06-19
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structural basis of actin filament nucleation by tandem w domains.
Cell Rep, 3, 2013
5T2P
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HEPATITIS B VIRUS CORE PROTEIN Y132A MUTANT IN COMPLEX WITH SULFAMOYLBENZAMIDE (SBA_R01)
Descriptor:Core protein, 4-fluoranyl-3-(4-oxidanylpiperidin-1-yl)sulfonyl-~{N}-[3,4,5-tris(fluoranyl)phenyl]benzamide, ISOPROPYL ALCOHOL, ...
Authors:Zhou, Z., Xu, Z.H.
Deposit date:2016-08-24
Release date:2017-02-22
Method:X-RAY DIFFRACTION (1.693 Å)
Cite:Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms
Sci Rep, 7, 2017
5WRE
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HEPATITIS B VIRUS CORE PROTEIN Y132A MUTANT IN COMPLEX WITH HETEROARYLDIHYDROPYRIMIDINE (HAP_R01)
Descriptor:Core protein, (2S)-1-[[(4R)-4-(2-chloranyl-4-fluoranyl-phenyl)-5-methoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-4,4-bis(fluoranyl)pyrrolidine-2-carboxylic acid, ISOPROPYL ALCOHOL, ...
Authors:Zhou, Z., Xu, Z.H.
Deposit date:2016-12-01
Release date:2017-02-22
Method:X-RAY DIFFRACTION (1.946 Å)
Cite:Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms
Sci Rep, 7, 2017
5WTW
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HEPATITIS B VIRUS CORE PROTEIN Y132A MUTANT IN P 41 21 2 SPACE GROUP
Descriptor:Core protein, CHLORIDE ION
Authors:Zhou, Z., Xu, Z.H.
Deposit date:2016-12-15
Release date:2017-02-22
Method:X-RAY DIFFRACTION (2.623 Å)
Cite:Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms
Sci Rep, 7, 2017