Author results

1ZXF
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SOLUTION STRUCTURE OF A SELF-SACRIFICING RESISTANCE PROTEIN, CALC FROM MICROMONOSPORA ECHINOSPORA
分子名称:CalC
著者Singh, S., Hager, M.H., Zhang, C., Griffith, B.R., Lee, M.S., Hallenga, K., Markley, J.L., Thorson, J.S., Center for Eukaryotic Structural Genomics (CESG)
登録日2005-06-08
公開日2005-12-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural insight into the self-sacrifice mechanism of enediyne resistance.
Acs Chem.Biol., 1, 2006
1IIM
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THYMIDYLYLTRANSFERASE COMPLEXED WITH TTP
分子名称:glucose-1-phosphate thymidylyltransferase, THYMIDINE-5'-TRIPHOSPHATE
著者Barton, W.A., Lesniak, J., Biggins, J.B., Jeffrey, P.D., Jiang, J., Rajashankar, K.R., Thorson, J.S., Nikolov, D.B.
登録日2001-04-23
公開日2001-05-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
Nat.Struct.Biol., 8, 2001
1IIN
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THYMIDYLYLTRANSFERASE COMPLEXED WITH UDP-GLUCOSE
分子名称:glucose-1-phosphate thymidylyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Barton, W.A., Lesniak, J., Biggins, J.B., Jeffrey, P.D., Jiang, J., Rajashankar, K.R., Thorson, J.S., Nikolov, D.B.
登録日2001-04-23
公開日2001-05-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
Nat.Struct.Biol., 8, 2001
1MP4
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W224H VARIANT OF S. ENTERICA RMLA
分子名称:W224H Variant of S. Enterica RmlA Bound to UDP-Glucose, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Barton, W.A., Biggins, J.B., Jiang, J., Thorson, J.S., Nikolov, D.B.
登録日2002-09-11
公開日2002-10-09
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
1MP5
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Y177F VARIANT OF S. ENTERICA RMLA
分子名称:Y177F VARIANT OF S. ENTERICA RmlA BOUND TO UDP-GLUCOSE, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Barton, W.A., Biggins, J.B., Jiang, J., Thorson, J.S., Nikolov, D.B.
登録日2002-09-11
公開日2002-10-09
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
2GKD
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STRUCTURAL INSIGHT INTO SELF-SACRIFICE MECHANISM OF ENEDIYNE RESISTANCE
分子名称:5'-D(*GP*CP*AP*TP*AP*TP*GP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*CP*AP*TP*AP*TP*GP*C)-3', CalC
著者Singh, S., Thorson, J.S.
登録日2006-04-01
公開日2006-08-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural insight into the self-sacrifice mechanism of enediyne resistance.
Acs Chem.Biol., 1, 2006
2L65
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HADDOCK CALCULATED MODEL OF THE COMPLEX OF THE RESISTANCE PROTEIN CALC AND CALICHEAMICIN-GAMMA
分子名称:CalC, 4,6-DIDEOXY-4-AMINO-BETA-D-GLUCOPYRANOSIDE, 2,6-DIDEOXY-4-THIO-BETA-D-ALLOSEPYRANOSIDE, ...
著者Singh, S., Markley, J.L., Thorson, J.S., Center for Eukaryotic Structural Genomics (CESG)
登録日2010-11-15
公開日2011-03-02
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural insight into the self-sacrifice mechanism of enediyne resistance.
Acs Chem.Biol., 1, 2006
2LUZ
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SOLUTION NMR STRUCTURE OF CALU16 FROM MICROMONOSPORA ECHINOSPORA, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET MIR12
分子名称:CalU16
著者Ramelot, T.A., Yang, Y., Lee, H., Pederson, K., Lee, D., Kohan, E., Janjua, H., Xiao, R., Acton, T.B., Everett, J.K., Wrobel, R.L., Bingman, C.A., Singh, S., Thorson, J.S., Prestegard, J.H., Montelione, G.T., Phillips Jr., G.N., Kennedy, M.A., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Northeast Structural Genomics Consortium (NESG)
登録日2012-06-22
公開日2012-10-03
最終更新日2014-11-12
実験手法SOLUTION NMR
主引用文献Structure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19.
Acs Chem.Biol., 9, 2014
3BUJ
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CRYSTAL STRUCTURE OF CALO2
分子名称:CalO2, PROTOPORPHYRIN IX CONTAINING FE
著者McCoy, J.G., Johnson, H.D., Singh, S., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N.
登録日2008-01-02
公開日2008-04-29
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Structural characterization of CalO2: a putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway.
Proteins, 74, 2009
3BUS
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CRYSTAL STRUCTURE OF REBM
分子名称:Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者McCoy, J.G., Singh, S., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N.
登録日2008-01-03
公開日2008-03-25
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM.
J.Biol.Chem., 283, 2008
3GWZ
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STRUCTURE OF THE MITOMYCIN 7-O-METHYLTRANSFERASE MMCR
分子名称:MmcR, CALCIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
著者Singh, S., Chang, A., Bingman, C.A., Phillips Jr., G.N., Thorson, J.S.
登録日2009-04-01
公開日2010-04-07
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structural characterization of the mitomycin 7-O-methyltransferase.
Proteins, 79, 2011
3GXO
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STRUCTURE OF THE MITOMYCIN 7-O-METHYLTRANSFERASE MMCR WITH BOUND MITOMYCIN A
分子名称:MmcR, S-ADENOSYL-L-HOMOCYSTEINE, [(1aS,8S,8aR,8bS)-6,8a-dimethoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate, ...
著者Singh, S., Chang, A., Bingman, C.A., Phillips Jr., G.N., Thorson, J.S.
登録日2009-04-02
公開日2010-04-21
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural characterization of the mitomycin 7-O-methyltransferase.
Proteins, 79, 2011
3IA7
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CRYSTAL STRUCTURE OF CALG4, THE CALICHEAMICIN GLYCOSYLTRANSFERASE
分子名称:CalG4, CALCIUM ION, CHLORIDE ION
著者Chang, A., Singh, S., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N.
登録日2009-07-13
公開日2010-06-02
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
3IAA
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CRYSTAL STRUCTURE OF CALG2, CALICHEAMICIN GLYCOSYLTRANSFERASE, TDP BOUND FORM
分子名称:CalG2, THYMIDINE-5'-DIPHOSPHATE
著者Chang, A., Singh, S., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N.
登録日2009-07-13
公開日2010-06-02
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.505 Å)
主引用文献Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
3LST
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CRYSTAL STRUCTURE OF CALO1, METHYLTRANSFERASE IN CALICHEAMICIN BIOSYNTHESIS, SAH BOUND FORM
分子名称:CalO1 Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 1,2-ETHANEDIOL
著者Chang, A., Singh, S., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Center for Eukaryotic Structural Genomics (CESG)
登録日2010-02-12
公開日2010-03-02
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 67, 2011
3OTG
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CRYSTAL STRUCTURE OF CALG1, CALICHEAMICIN GLYCOSTYLTRANSFERASE, TDP BOUND FORM
分子名称:CalG1, THYMIDINE-5'-DIPHOSPHATE, CHLORIDE ION
著者Chang, A., Singh, S., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2010-09-11
公開日2010-12-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OTH
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CRYSTAL STRUCTURE OF CALG1, CALICHEAMICIN GLYCOSTYLTRANSFERASE, TDP AND CALICHEAMICIN ALPHA3I BOUND FORM
分子名称:CalG1, THYMIDINE-5'-DIPHOSPHATE, Calicheamicin alpha3I
著者Chang, A., Singh, S., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2010-09-11
公開日2010-12-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OTI
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CRYSTAL STRUCTURE OF CALG3, CALICHEAMICIN GLYCOSTYLTRANSFERASE, TDP AND CALICHEAMICIN T0 BOUND FORM
分子名称:CalG3, THYMIDINE-5'-DIPHOSPHATE, Calicheamicin T0, ...
著者Chang, A., Singh, S., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2010-09-11
公開日2010-12-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.597 Å)
主引用文献Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PKP
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Q83S VARIANT OF S. ENTERICA RMLA WITH DATP
分子名称:Glucose-1-phosphate thymidylyltransferase, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION
著者Chang, A., Moretti, R., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Center for Eukaryotic Structural Genomics (CESG)
登録日2010-11-11
公開日2011-01-12
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution.
J.Biol.Chem., 286, 2011
3PKQ
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Q83D VARIANT OF S. ENTERICA RMLA WITH DGTP
分子名称:Glucose-1-phosphate thymidylyltransferase, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Chang, A., Moretti, R., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Center for Eukaryotic Structural Genomics (CESG)
登録日2010-11-11
公開日2011-01-12
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution.
J.Biol.Chem., 286, 2011
3RSC
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CRYSTAL STRUCTURE OF CALG2, CALICHEAMICIN GLYCOSYLTRANSFERASE, TDP AND CALICHEAMICIN T0 BOUND FORM
分子名称:CalG2, THYMIDINE-5'-DIPHOSPHATE, Calicheamicin T0, ...
著者Chang, A., Helmich, K.E., Singh, S., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2011-05-02
公開日2011-08-10
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TOS
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CRYSTAL STRUCTURE OF CALS11, CALICHEAMICIN METHYLTRANSFERASE
分子名称:CalS11, S-ADENOSYL-L-HOMOCYSTEINE, GLUTAMIC ACID, ...
著者Chang, A., Aceti, D.J., Beebe, E.T., Makino, S.-I., Wrobel, R.L., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2011-09-06
公開日2011-10-05
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal Structure of CalS11, Calicheamicin methyltransferase
To be Published
4FZR
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CRYSTAL STRUCTURE OF SSFS6, STREPTOMYCES SP. SF2575 GLYCOSYLTRANSFERASE
分子名称:SsfS6
著者Wang, F., Zhou, M., Singh, S., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2012-07-07
公開日2012-07-25
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis.
Proteins, 81, 2013
4G2T
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CRYSTAL STRUCTURE OF STREPTOMYCES SP. SF2575 GLYCOSYLTRANSFERASE SSFS6, COMPLEXED WITH THYMIDINE DIPHOSPHATE
分子名称:SsfS6, THYMIDINE-5'-DIPHOSPHATE
著者Wang, F., Zhou, M., Singh, S., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2012-07-12
公開日2012-07-25
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.405 Å)
主引用文献Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis.
Proteins, 81, 2013
4HPV
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CRYSTAL STRUCTURE OF S-ADENOSYLMETHIONINE SYNTHETASE FROM SULFOLOBUS SOLFATARICUS
分子名称:S-adenosylmethionine synthase
著者Wang, F., Hurley, K.A., Helmich, K.E., Singh, S., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2012-10-24
公開日2012-11-14
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.214 Å)
主引用文献Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus.
Febs J., 281, 2014
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