7OZZ
| The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG with LNA-amide modification | Descriptor: | DNA (5'-D(*CP*TP*(05H)P*TP*CP*TP*TP*TP*G)-3'), POTASSIUM ION, RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3') | Authors: | Thorpe, C, Hardwick, J, McDonough, M.A, Hall, J.P, Baker, Y.R, El-Sagheer, A.H, Brown, T. | Deposit date: | 2021-06-29 | Release date: | 2022-08-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides. Nat Commun, 13, 2022
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7NRP
| The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG | Descriptor: | CACODYLATE ION, DNA (5'-D(*CP*TP*TP*TP*TP*CP*TP*TP*TP*G)-3'), RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3') | Authors: | Thorpe, C, Hardwick, J, McDonough, M.A, Hall, J.P, Baker, Y.R, El-Sagheer, A.H, Brown, T. | Deposit date: | 2021-03-04 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides. Nat Commun, 13, 2022
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7OOO
| The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG containing an LNA-Amide-LNA modification | Descriptor: | DNA (5'-D(*CP*TP*(05A)P*TP*CP*TP*TP*TP*G)-3'), MAGNESIUM ION, RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3') | Authors: | Thorpe, C, Hardwick, J, McDonough, M.A, Hall, J.P, Baker, Y.R, El-Sagheer, A.H, Brown, T. | Deposit date: | 2021-05-28 | Release date: | 2022-08-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides. Nat Commun, 13, 2022
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7OOS
| The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG | Descriptor: | DNA (5'-D(*CP*TP*(05K)P*TP*CP*TP*TP*TP*G)-3'), RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3'), STRONTIUM ION | Authors: | Thorpe, C, Hardwick, J, McDonough, M.A, Hall, J.P, Baker, Y.R, El-Sagheer, A.H, Brown, T. | Deposit date: | 2021-05-28 | Release date: | 2022-08-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides. Nat Commun, 13, 2022
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4LDK
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3MBG
| Crystal Structure of Human Augmenter of Liver Regeneration (ALR) | Descriptor: | ACETATE ION, FAD-linked sulfhydryl oxidase ALR, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Dong, M, Schaefer, S, Daithankar, V.N, Thorpe, C, Bahnson, B.J. | Deposit date: | 2010-03-25 | Release date: | 2010-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of the human sulfhydryl oxidase augmenter of liver regeneration and characterization of a human mutation causing an autosomal recessive myopathy . Biochemistry, 49, 2010
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3LLI
| Sulfhydryl Oxidase Fragment of Human QSOX1 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Sulfhydryl oxidase 1 | Authors: | Alon, A, Fass, D. | Deposit date: | 2010-01-29 | Release date: | 2010-03-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | QSOX contains a pseudo-dimer of functional and degenerate sulfhydryl oxidase domains. Febs Lett., 584, 2010
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3LLK
| Sulfhydryl Oxidase Fragment of Human QSOX1 | Descriptor: | CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, Sulfhydryl oxidase 1 | Authors: | Alon, A, Fass, D. | Deposit date: | 2010-01-29 | Release date: | 2010-03-31 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | QSOX contains a pseudo-dimer of functional and degenerate sulfhydryl oxidase domains. Febs Lett., 584, 2010
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3T58
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3T59
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3U5S
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3Q6O
| Oxidoreductase Fragment of Human QSOX1 | Descriptor: | SULFATE ION, Sulfhydryl oxidase 1 | Authors: | Fass, D, Alon, A. | Deposit date: | 2011-01-03 | Release date: | 2012-05-30 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The dynamic disulphide relay of quiescin sulphydryl oxidase. Nature, 488, 2012
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3QD9
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3QCP
| QSOX from Trypanosoma brucei | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, QSOX from Trypanosoma brucei (TbQSOX) | Authors: | Alon, A, Fass, D. | Deposit date: | 2011-01-17 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The dynamic disulphide relay of quiescin sulphydryl oxidase. Nature, 488, 2012
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