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1ST7
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SOLUTION STRUCTURE OF ACYL COENZYME A BINDING PROTEIN FROM YEAST
Descriptor:Acyl-CoA-binding protein
Authors:Teilum, K., Thormann, T., Caterer, N.R., Poulsen, H.I., Jensen, P.H., Knudsen, J., Kragelund, B.B., Poulsen, F.M.
Deposit date:2004-03-25
Release date:2005-03-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Different secondary structure elements as scaffolds for protein folding transition states of two homologous four-helix bundles
Proteins, 59, 2005
4W1O
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PDE4D COMPLEXED WITH INHIBITOR
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, N-(3,5-dichloropyridin-4-yl)-3-[(3-ethyl-1,2-oxazol-5-yl)methoxy]-4-methoxybenzamide, ZINC ION
Authors:Sorensen, M.D.
Deposit date:2014-08-14
Release date:2014-11-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery and Early Clinical Development of 2-{6-[2-(3,5-Dichloro-4-pyridyl)acetyl]-2,3-dimethoxyphenoxy}-N-propylacetamide (LEO 29102), a Soft-Drug Inhibitor of Phosphodiesterase 4 for Topical Treatment of Atopic Dermatitis
J.Med.Chem, 57, 2014
4WCU
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PDE4 COMPLEXED WITH INHIBITOR
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, N-benzyl-2-{6-[(3,5-dichloropyridin-4-yl)acetyl]-2,3-dimethoxyphenoxy}acetamide, ZINC ION, ...
Authors:Sorensen, M.D.
Deposit date:2014-09-05
Release date:2014-10-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Discovery and Early Clinical Development of 2-{6-[2-(3,5-Dichloro-4-pyridyl)acetyl]-2,3-dimethoxyphenoxy}-N-propylacetamide (LEO 29102), a Soft-Drug Inhibitor of Phosphodiesterase 4 for Topical Treatment of Atopic Dermatitis.
J. Med. Chem., 57, 2014
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