5FV7
| Human Fen1 in complex with an N-hydroxyurea compound | Descriptor: | 1-[(2S)-2,3-dihydro-1,4-benzodioxin-2-ylmethyl]-3-hydroxythieno[3,2-d]pyrimidine-2,4(1H,3H)-dione, FLAP ENDONUCLEASE 1, MAGNESIUM ION | Authors: | Exell, J.C, Thompson, M.J, Finger, L.D, Shaw, S.K, Abbott, W.M, McWhirter, C, Debreczeni, J.E, Jones, C.D, Nissink, J.W.M, Ward, T.A, Sioberg, C.W.L, Molina, D.M, Durant, S.T, Grasby, J.A. | Deposit date: | 2016-02-03 | Release date: | 2016-08-17 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Cellular Active N-Hydroxyurea Fen1 Inhibitors Block Substrate Entry to the Active Site Nat.Chem.Biol., 12, 2016
|
|
2ONX
| NNQQ peptide corresponding to residues 8-11 of yeast prion sup35 (alternate crystal form) | Descriptor: | peptide corresponding to residues 8-11 of yeast prion sup35 | Authors: | Sawaya, M.R, Sambashivan, S, Nelson, R, Ivanova, M, Sievers, S.A, Apostol, M.I, Thompson, M.J, Balbirnie, M, Wiltzius, J.J, McFarlane, H, Madsen, A.O, Riekel, C, Eisenberg, D. | Deposit date: | 2007-01-24 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature, 447, 2007
|
|
7QL5
| Torpedo muscle-type nicotinic acetylcholine receptor - nicotine-bound conformation | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zarkadas, E, Pebay-Peyroula, E, Baenziger, J, Nury, H. | Deposit date: | 2021-12-19 | Release date: | 2022-02-09 | Last modified: | 2022-05-04 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor. Neuron, 110, 2022
|
|
7QKO
| Torpedo muscle-type nicotinic acetylcholine receptor - Resting conformation | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Acetylcholine receptor subunit alpha, Acetylcholine receptor subunit beta, ... | Authors: | Zarkadas, E, Pebay-Peyroula, E, Baenziger, J, Nury, H. | Deposit date: | 2021-12-18 | Release date: | 2022-02-09 | Last modified: | 2022-05-04 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor. Neuron, 110, 2022
|
|
7QL6
| Torpedo muscle-type nicotinic acetylcholine receptor - carbamylcholine-bound conformation | Descriptor: | 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zarkadas, E, Pebay-Peyroula, E, Baenziger, J, Nury, H. | Deposit date: | 2021-12-19 | Release date: | 2022-02-09 | Last modified: | 2022-05-04 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor. Neuron, 110, 2022
|
|
5K97
| Flap endonuclease 1 (FEN1) D233N with cleaved product fragment and Sm3+ | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*AP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*T)-3'), ... | Authors: | Tsutakawa, S.E, Arvai, A.S, Tainer, J.A. | Deposit date: | 2016-05-31 | Release date: | 2017-06-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability. Nat Commun, 8, 2017
|
|
5KSE
| Flap endonuclease 1 (FEN1) R100A with 5'-flap substrate DNA and Sm3+ | Descriptor: | DNA (5'-D(*AP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*AP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*T)-3'), DNA (5'-D(P*TP*AP*AP*TP*TP*GP*AP*GP*GP*CP*AP*GP*AP*GP*T)-3'), ... | Authors: | Tsutakawa, S.E, Arvai, A.S, Tainer, J.A. | Deposit date: | 2016-07-08 | Release date: | 2017-06-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.105 Å) | Cite: | Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability. Nat Commun, 8, 2017
|
|
5UM9
| Flap endonuclease 1 (FEN1) D86N with 5'-flap substrate DNA and Sm3+ | Descriptor: | DNA (5'-D(*AP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*AP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*T)-3'), DNA (5'-D(P*TP*CP*TP*TP*GP*AP*GP*GP*CP*AP*GP*AP*GP*T)-3'), ... | Authors: | Tsutakawa, S.E, Arvai, A.S, Tainer, J.A. | Deposit date: | 2017-01-26 | Release date: | 2017-06-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.805 Å) | Cite: | Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability. Nat Commun, 8, 2017
|
|
2OMM
| |
2OMQ
| |
2ON9
| |
2OKZ
| |
2OLX
| |
2ONA
| |
2OL9
| |
2OMP
| |
2ONV
| |
2ONW
| |
2H2J
| Structure of Rubisco LSMT bound to Sinefungin and Monomethyllysine | Descriptor: | N-METHYL-LYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, SINEFUNGIN | Authors: | Couture, J.F, Hauk, G, Trievel, R.C. | Deposit date: | 2006-05-18 | Release date: | 2006-05-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases. J.Biol.Chem., 281, 2006
|
|
2H2E
| Structure of Rubisco LSMT bound to AzaAdoMet and Lysine | Descriptor: | LYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE | Authors: | Couture, J.F, Hauk, G, Trievel, R.C. | Deposit date: | 2006-05-18 | Release date: | 2006-05-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases. J.Biol.Chem., 281, 2006
|
|
2H21
| Structure of Rubisco LSMT bound to AdoMet | Descriptor: | Ribulose-1,5 bisphosphate carboxylase/oxygenase, S-ADENOSYLMETHIONINE | Authors: | Couture, J.F, Hauk, G, Trievel, R.C. | Deposit date: | 2006-05-17 | Release date: | 2006-05-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases. J.Biol.Chem., 281, 2006
|
|
2H23
| Structure of Rubisco LSMT bound to Trimethyllysine and AdoHcy | Descriptor: | N-TRIMETHYLLYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Couture, J.F, Hauk, G, Trievel, R.C. | Deposit date: | 2006-05-17 | Release date: | 2006-05-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases. J.Biol.Chem., 281, 2006
|
|