Author results

1RA6
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POLIOVIRUS POLYMERASE FULL LENGTH APO STRUCTURE
Descriptor:Genome polyprotein, ACETIC ACID
Authors:Thompson, A.A., Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
1RA7
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POLIOVIRUS POLYMERASE WITH GTP
Descriptor:Genome polyprotein, GUANOSINE-5'-TRIPHOSPHATE, ACETIC ACID
Authors:Thompson, A.A., Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
1RAJ
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POLIOVIRUS POLYMERASE WITH A 68 RESIDUE N-TERMINAL TRUNCATION
Descriptor:Genome polyprotein
Authors:Thompson, A.A., Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
1TQL
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POLIOVIRUS POLYMERASE G1A MUTANT
Descriptor:RNA-directed RNA polymerase, ACETIC ACID
Authors:Thompson, A.A., Peersen, O.B.
Deposit date:2004-06-17
Release date:2004-08-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase
Embo J., 23, 2004
2ILY
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CRYSTAL STRUCTURE OF POLIOVIRUS POLYMERASE COMPLEXED WITH ATP AND MG2+
Descriptor:Poliovirus polymerase, SODIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Thompson, A.A., Peersen, O.B.
Deposit date:2006-10-03
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
2ILZ
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CRYSTAL STRUCTURE OF POLIOVIRUS POLYMERASE COMPLEXED WITH GTP AND MN2+
Descriptor:poliovirus polymerase, MANGANESE (II) ION, SODIUM ION, ...
Authors:Thompson, A.A., Peersen, O.B.
Deposit date:2006-10-03
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
2IM0
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CRYSTAL STRUCTURE OF POLIOVIRUS POLYMERASE COMPLEXED WITH CTP AND MG2+
Descriptor:poliovirus polymerase, SODIUM ION, CYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Thompson, A.A., Peersen, O.B.
Deposit date:2006-10-03
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
2IM1
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CRYSTAL STRUCTURE OF POLIOVIRUS POLYMERASE COMPLEXED WITH CTP AND MN2+
Descriptor:poliovirus polymerase, MANGANESE (II) ION, SODIUM ION, ...
Authors:Thompson, A.A., Peersen, O.B.
Deposit date:2006-10-03
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
2IM2
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CRYSTAL STRUCTURE OF POLIOVIRUS POLYMERASE COMPLEXED WITH UTP AND MG2+
Descriptor:poliovirus polymerase, SODIUM ION, URIDINE 5'-TRIPHOSPHATE, ...
Authors:Thompson, A.A., Peersen, O.B.
Deposit date:2006-10-03
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
2IM3
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CRYSTAL STRUCTURE OF POLIOVIRUS POLYMERASE COMPLEXED WITH UTP AND MN2+
Descriptor:poliovirus polymerase, MANGANESE (II) ION, SODIUM ION, ...
Authors:Thompson, A.A., Peersen, O.B.
Deposit date:2006-10-03
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
3QIX
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CRYSTAL STRUCTURE OF BONT/A LC WITH ZINC BOUND
Descriptor:Botulinum neurotoxin type A, 1,2-ETHANEDIOL, ZINC ION
Authors:Thompson, A.A., Han, G.W., Stevens, R.C.
Deposit date:2011-01-28
Release date:2011-04-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.413 Å)
Cite:Structural Characterization of Three Novel Hydroxamate-Based Zinc Chelating Inhibitors of the Clostridium botulinum Serotype A Neurotoxin Light Chain Metalloprotease Reveals a Compact Binding Site Resulting from 60/70 Loop Flexibility.
Biochemistry, 50, 2011
3QIY
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CRYSTAL STRUCTURE OF BONT/A LC COMPLEXED WITH HYDROXAMATE-BASED INHIBITOR PT-1
Descriptor:Botulinum neurotoxin type A, ZINC ION, 4-[bis(4-chlorobenzyl)amino]-N-hydroxybutanamide, ...
Authors:Thompson, A.A., Han, G.W., Stevens, R.C.
Deposit date:2011-01-28
Release date:2011-04-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Characterization of Three Novel Hydroxamate-Based Zinc Chelating Inhibitors of the Clostridium botulinum Serotype A Neurotoxin Light Chain Metalloprotease Reveals a Compact Binding Site Resulting from 60/70 Loop Flexibility.
Biochemistry, 50, 2011
3QIZ
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CRYSTAL STRUCTURE OF BONT/A LC COMPLEXED WITH HYDROXAMATE-BASED INHIBITOR PT-2
Descriptor:Botulinum neurotoxin type A, ZINC ION, (2S,4R)-2-(2-{[3-(4-fluoro-3-methylphenyl)propyl](methyl)amino}ethyl)-4-(4-fluorophenyl)-N-hydroxy-4-methoxybutanamide, ...
Authors:Thompson, A.A., Han, G.W., Stevens, R.C.
Deposit date:2011-01-28
Release date:2011-04-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Characterization of Three Novel Hydroxamate-Based Zinc Chelating Inhibitors of the Clostridium botulinum Serotype A Neurotoxin Light Chain Metalloprotease Reveals a Compact Binding Site Resulting from 60/70 Loop Flexibility.
Biochemistry, 50, 2011
3QJ0
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CRYSTAL STRUCTURE OF BONT/A LC COMPLEXED WITH HYDROXAMATE-BASED INHIBITOR PT-3
Descriptor:Botulinum neurotoxin type A, ZINC ION, (4R)-4-(4-chlorophenoxy)-1-[(4-chlorophenyl)sulfonyl]-N-hydroxy-L-prolinamide, ...
Authors:Thompson, A.A., Han, G.W., Stevens, R.C.
Deposit date:2011-01-28
Release date:2011-04-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural Characterization of Three Novel Hydroxamate-Based Zinc Chelating Inhibitors of the Clostridium botulinum Serotype A Neurotoxin Light Chain Metalloprotease Reveals a Compact Binding Site Resulting from 60/70 Loop Flexibility.
Biochemistry, 50, 2011
4EA3
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STRUCTURE OF THE N/OFQ OPIOID RECEPTOR IN COMPLEX WITH A PEPTIDE MIMETIC
Descriptor:Fusion protein of Nociceptin receptor and cytochrome b562, 1-benzyl-N-[3-(1'H,3H-spiro[2-benzofuran-1,4'-piperidin]-1'-yl)propyl]-D-prolinamide, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
Authors:Thompson, A.A., Liu, W., Chun, E., Katritch, V., Wu, H., Vardy, E., Huang, X.P., Trapella, C., Guerrini, R., Calo, G., Roth, B.L., Cherezov, V., Stevens, R.C., GPCR Network (GPCR)
Deposit date:2012-03-22
Release date:2012-04-25
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.013 Å)
Cite:Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic.
Nature, 485, 2012
3EVA
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CRYSTAL STRUCTURE OF YELLOW FEVER VIRUS METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thompson, A.A., Geiss, B.J., Peersen, O.B.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVB
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CRYSTAL STRUCTURE OF YELLOW FEVER VIRUS METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thompson, A.A., Geiss, B.J., Peersen, O.B.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVC
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CRYSTAL STRUCTURE OF GTP COMPLEX OF YELLOW FEVER VIRUS METHYLTRANSFERASE AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE, GUANOSINE-5'-TRIPHOSPHATE
Authors:Thompson, A.A., Geiss, B.J., Peersen, O.B.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVD
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CRYSTAL STRUCTURE OF GTP COMPLEX OF YELLOW FEVER VIRUS METHYLTRANSFERASE AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:RNA-directed RNA polymerase NS5, GUANOSINE-5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thompson, A.A., Geiss, B.J., Peersen, O.B.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVE
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CRYSTAL STRUCTURE OF GPPPA COMPLEX OF YELLOW FEVER VIRUS METHYLTRANSFERASE AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:RNA-directed RNA polymerase NS5, GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thompson, A.A.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVF
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CRYSTAL STRUCTURE OF ME7-GPPPA COMPLEX OF YELLOW FEVER VIRUS METHYLTRANSFERASE AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:RNA-directed RNA polymerase NS5, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thompson, A.A., Geiss, B.J., Peersen, O.B.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVG
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CRYSTAL STRUCTURE OF DENGUE-2 VIRUS METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:RNA-directed RNA polymerase NS5, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thompson, A.A., Geiss, B.J., Peersen, O.B.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3K3Q
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CRYSTAL STRUCTURE OF A LLAMA ANTIBODY COMPLEXED WITH THE C. BOTULINUM NEUROTOXIN SEROTYPE A CATALYTIC DOMAIN
Descriptor:llama Aa1 VHH domain, Botulinum neurotoxin type A, ZINC ION
Authors:Thompson, A.A., Dong, J., Marks, J.D., Stevens, R.C.
Deposit date:2009-10-04
Release date:2010-02-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic alpha-Exosite Binding Region.
J.Mol.Biol., 397, 2010
4DJH
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STRUCTURE OF THE HUMAN KAPPA OPIOID RECEPTOR IN COMPLEX WITH JDTIC
Descriptor:Kappa-type opioid receptor, Lysozyme, (3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, ...
Authors:Wu, H., Wacker, D., Katritch, V., Mileni, M., Han, G.W., Vardy, E., Liu, W., Thompson, A.A., Huang, X.P., Carroll, F.I., Mascarella, S.W., Westkaemper, R.B., Mosier, P.D., Roth, B.L., Cherezov, V., Stevens, R.C., GPCR Network (GPCR)
Deposit date:2012-02-01
Release date:2012-03-21
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:tructure of the human kappa-opioid receptor in complex with JDTic
Nature, 485, 2012
4EIY
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CRYSTAL STRUCTURE OF THE CHIMERIC PROTEIN OF A2AAR-BRIL IN COMPLEX WITH ZM241385 AT 1.8A RESOLUTION
Descriptor:Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ...
Authors:Liu, W., Chun, E., Thompson, A.A., Chubukov, P., Xu, F., Katritch, V., Han, G.W., Heitman, L.H., Ijzerman, A.P., Cherezov, V., Stevens, R.C., GPCR Network (GPCR)
Deposit date:2012-04-06
Release date:2012-07-25
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for allosteric regulation of GPCRs by sodium ions.
Science, 337, 2012
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