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1E3G
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HUMAN ANDROGEN RECEPTOR LIGAND BINDING IN COMPLEX WITH THE LIGAND METRIBOLONE (R1881)
Descriptor:ANDROGEN RECEPTOR, (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE
Authors:Matias, P.M., Donner, P., Coelho, R., Thomaz, M., Peixoto, C., Macedo, S., Otto, N., Joschko, S., Scholz, P., Wegg, A., Basler, S., Schafer, M., Ruff, M., Egner, U., Carrondo, M.A.
Deposit date:2000-06-14
Release date:2001-06-14
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations.
J. Biol. Chem., 275, 2000
1E3K
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HUMAN PROGESTERON RECEPTOR LIGAND BINDING DOMAIN IN COMPLEX WITH THE LIGAND METRIBOLONE (R1881)
Descriptor:PROGESTERONE RECEPTOR, (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE
Authors:Matias, P.M., Donner, P., Coelho, R., Thomaz, M., Peixoto, C., Macedo, S., Otto, N., Joschko, S., Scholz, P., Wegg, A., Basler, S., Schafer, M., Egner, U., Carrondo, M.A.
Deposit date:2000-06-19
Release date:2001-06-14
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations.
J. Biol. Chem., 275, 2000
2A8F
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BETA-CINNAMOMIN AFTER STEROL REMOVAL
Descriptor:Beta-elicitin cinnamomin
Authors:Rodrigues, M.L., Archer, M., Martel, P., Miranda, S., Thomaz, M., Enguita, F.J., Baptista, R.P., Melo, E.P., Sousa, N., Cravador, A., Carrondo, M.A.
Deposit date:2005-07-08
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structures of the free and sterol-bound forms of beta-cinnamomin
Biochim.Biophys.Acta, 1764, 2006
2AIB
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BETA-CINNAMOMIN IN COMPLEX WITH ERGOSTEROL
Descriptor:Beta-elicitin cinnamomin, ERGOSTEROL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Rodrigues, M.L., Archer, M., Martel, P., Miranda, S., Thomaz, M., Enguita, F.J., Baptista, R.P., Melo, E.P., Sousa, N., Cravador, A., Carrondo, M.A.
Deposit date:2005-07-29
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structures of the free and sterol-bound forms of beta-cinnamomin
Biochim.Biophys.Acta, 1764, 2006
2V5Q
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CRYSTAL STRUCTURE OF WILD-TYPE PLK-1 KINASE DOMAIN IN COMPLEX WITH A SELECTIVE DARPIN
Descriptor:SERINE/THREONINE-PROTEIN KINASE PLK1, DESIGN ANKYRIN REPEAT PROTEIN
Authors:Bandeiras, T.M., Hillig, R.C., Matias, P.M., Eberspaecher, U., Fanghaenel, J., Thomaz, M., Miranda, S., Crusius, K., Puetter, V., Amstutz, P., Gulotti-Georgieva, M., Binz, H.K., Holz, C., Schmitz, A.A.P., Lang, C., Donner, P., Egner, U., Carrondo, M.A., Mueller-Tiemann, B.
Deposit date:2007-07-08
Release date:2008-04-01
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin.
Acta Crystallogr. D Biol. Crystallogr., 64, 2008
1GS4
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STRUCTURAL BASIS FOR THE GLUCOCORTICOID RESPONSE IN A MUTANT HUMAN ANDROGEN RECEPTOR (ARCCR) DERIVED FROM AN ANDROGEN-INDEPENDENT PROSTATE CANCER
Descriptor:ANDROGEN RECEPTOR, 9ALPHA-FLUOROCORTISOL, PHOSPHATE ION
Authors:Matias, P.M., Carrondo, M.A., Coelho, R., Thomaz, M., Zhao, X.-Y., Wegg, A., Crusius, K., Egner, U., Donner, P.
Deposit date:2001-12-27
Release date:2003-01-16
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis for the Glucocorticoid Response in a Mutant Human Androgen Receptor (Ar(Ccr)) Derived from an Androgen-Independent Prostate Cancer
J.Med.Chem., 45, 2002
2C9O
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3D STRUCTURE OF THE HUMAN RUVB-LIKE HELICASE RUVBL1
Descriptor:RUVB-LIKE 1, ADENOSINE-5'-DIPHOSPHATE
Authors:Matias, P.M., Gorynia, S., Donner, P., Carrondo, M.A.
Deposit date:2005-12-14
Release date:2006-10-23
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the human AAA+ protein RuvBL1.
J. Biol. Chem., 281, 2006