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2RH1
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HIGH RESOLUTION CRYSTAL STRUCTURE OF HUMAN B2-ADRENERGIC G PROTEIN-COUPLED RECEPTOR.
Descriptor:beta-2-adrenergic receptor/T4-lysozyme chimera, MALTOSE, SULFATE ION, ...
Authors:Cherezov, V., Rosenbaum, D.M., Hanson, M.A., Rasmussen, S.G.F., Thian, F.S., Kobilka, T.S., Choi, H.J., Kuhn, P., Weis, W.I., Kobilka, B.K., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
Deposit date:2007-10-05
Release date:2007-10-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.
Science, 318, 2007
2R4R
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CRYSTAL STRUCTURE OF THE HUMAN BETA2 ADRENOCEPTOR
Descriptor:Beta-2 adrenergic receptor, antibody for beta2 adrenoceptor, light chain, ...
Authors:Rasmussen, S.G.F., Choi, H.J., Rosenbaum, D.M., Kobilka, T.S., Thian, F.S., Edwards, P.C., Burghammer, M., Ratnala, V.R., Sanishvili, R., Fischetti, R.F., Schertler, G.F., Weis, W.I., Kobilka, B.K.
Deposit date:2007-08-31
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.
Nature, 450, 2007
2R4S
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CRYSTAL STRUCTURE OF THE HUMAN BETA2 ADRENOCEPTOR
Descriptor:Beta-2 adrenergic receptor, antibody for beta2 adrenoceptor, light chain, ...
Authors:Rasmussen, S.G.F., Choi, H.J., Rosenbaum, D.M., Kobilka, T.S., Thian, F.S., Edwards, P.C., Burghammer, M., Ratnala, V.R., Sanishvili, R., Fischetti, R.F., Schertler, G.F., Weis, W.I., Kobilka, B.K.
Deposit date:2007-08-31
Release date:2007-11-06
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.
Nature, 450, 2007
3KJ6
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CRYSTAL STRUCTURE OF A METHYLATED BETA2 ADRENERGIC RECEPTOR-FAB COMPLEX
Descriptor:Beta-2 adrenergic receptor, Fab light chain, Fab heavy chain, ...
Authors:Bokoch, M.P., Zou, Y., Rasmussen, S.G.F., Liu, C.W., Nygaard, R., Rosenbaum, D.M., Fung, J.J., Choi, H.-J., Thian, F.S., Kobilka, T.S., Puglisi, J.D., Weis, W.I., Pardo, L., Prosser, S., Mueller, L., Kobilka, B.K.
Deposit date:2009-11-02
Release date:2010-02-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Nature, 463, 2010
3P0G
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STRUCTURE OF A NANOBODY-STABILIZED ACTIVE STATE OF THE BETA2 ADRENOCEPTOR
Descriptor:Beta-2 adrenergic receptor, Lysozyme, Camelid Antibody Fragment, ...
Authors:Rasmussen, S.G.F., Choi, H.-J., Fung, J.J., Pardon, E., Casarosa, P., Chae, P.S., DeVree, B.T., Rosenbaum, D.M., Thian, F.S., Kobilka, T.S., Schnapp, A., Konetzki, I., Sunahara, R.K., Gellman, S.H., Pautsch, A., Steyaert, J., Weis, W.I., Kobilka, B.K.
Deposit date:2010-09-28
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a nanobody-stabilized active state of the b2 adrenoceptor
Nature, 469, 2011
3SN6
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CRYSTAL STRUCTURE OF THE BETA2 ADRENERGIC RECEPTOR-GS PROTEIN COMPLEX
Descriptor:Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Rasmussen, S.G.F., DeVree, B.T., Zou, Y., Kruse, A.C., Chung, K.Y., Kobilka, T.S., Thian, F.S., Chae, P.S., Pardon, E., Calinski, D., Mathiesen, J.M., Shah, S.T.A., Lyons, J.A., Caffrey, M., Gellman, S.H., Steyaert, J., Skiniotis, G., Weis, W.I., Sunahara, R.K., Kobilka, B.K.
Deposit date:2011-06-28
Release date:2011-07-20
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the beta2 adrenergic receptor-Gs protein complex
Nature, 477, 2011
4DKL
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CRYSTAL STRUCTURE OF THE MU-OPIOID RECEPTOR BOUND TO A MORPHINAN ANTAGONIST
Descriptor:Mu-type opioid receptor, lysozyme chimera, methyl 4-{[(5beta,6alpha)-17-(cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6-yl]amino}-4-oxobutanoate, ...
Authors:Manglik, A., Kruse, A.C., Kobilka, T.S., Thian, F.S., Mathiesen, J.M., Sunahara, R.K., Pardo, L., Weis, W.I., Kobilka, B.K., Granier, S.
Deposit date:2012-02-03
Release date:2012-03-21
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the {mu}-opioid receptor bound to a morphinan antagonist.
Nature, 485, 2012
4EJ4
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STRUCTURE OF THE DELTA OPIOID RECEPTOR BOUND TO NALTRINDOLE
Descriptor:Delta-type opioid receptor, Lysozyme chimera, (4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol
Authors:Granier, S., Manglik, A., Kruse, A.C., Kobilka, T.S., Thian, F.S., Weis, W.I., Kobilka, B.K.
Deposit date:2012-04-06
Release date:2012-05-16
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of the delta opioid receptor bound to naltrindole
Nature, 485, 2012