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2N3A
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SOLUTION STRUCTURE OF LEDGF/P75 IBD IN COMPLEX WITH POGZ PEPTIDE (1389-1404)
Descriptor:Pogo transposable element with ZNF domain, PC4 and SFRS1-interacting protein
Authors:Tesina, P., Cermakova, K., Horejsi, M., Prochazkova, K., Fabry, M., Sharma, S., Christ, F., Demeulemeester, J., Debyser, Z., De Rijck, J., Veverka, V., Rezacova, P.
Deposit date:2015-05-26
Release date:2015-08-19
Method:SOLUTION NMR
Cite:Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif.
Nat Commun, 6, 2015
6Q8Y
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CRYO-EM STRUCTURE OF THE MRNA TRANSLATING AND DEGRADING YEAST 80S RIBOSOME-XRN1 NUCLEASE COMPLEX
Descriptor:18S ribosomal RNA, 60S ribosomal protein L8-A, 60S ribosomal protein L23-A, ...
Authors:Tesina, P., Heckel, E., Cheng, J., Buschauer, R., Kater, L., Berninghausen, O., Becker, T., Beckmann, R.
Deposit date:2018-12-16
Release date:2019-03-13
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the 80S ribosome-Xrn1 nuclease complex.
Nat.Struct.Mol.Biol., 26, 2019
6T4Q
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STRUCTURE OF YEAST 80S RIBOSOME STALLED ON THE CGA-CCG INHIBITORY CODON COMBINATION.
Descriptor:18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S15, ...
Authors:Tesina, P., Buschauer, R., Cheng, J., Berninghausen, O., Becker, R., Beckmann, R.
Deposit date:2019-10-14
Release date:2019-12-25
Last modified:2020-02-12
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
6T7I
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STRUCTURE OF YEAST 80S RIBOSOME STALLED ON THE CGA-CGA INHIBITORY CODON COMBINATION.
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Tesina, P., Buschauer, R., Cheng, J., Berninghausen, O., Becker, R., Beckmann, R.
Deposit date:2019-10-22
Release date:2019-12-25
Last modified:2020-02-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
6T7T
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STRUCTURE OF YEAST 80S RIBOSOME STALLED ON POLY(A) TRACT.
Descriptor:60S ribosomal protein L2-A, 40S ribosomal protein S0-A, 60S ribosomal protein L3, ...
Authors:Tesina, P., Buschauer, R., Cheng, J., Berninghausen, O., Becker, R., Beckmann, R.
Deposit date:2019-10-23
Release date:2019-12-25
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
6T83
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STRUCTURE OF YEAST DISOME (DI-RIBOSOME) STALLED ON POLY(A) TRACT.
Descriptor:18S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Tesina, P., Buschauer, R., Cheng, J., Berninghausen, O., Becker, R., Beckmann, R.
Deposit date:2019-10-24
Release date:2019-12-25
Last modified:2020-02-12
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
6I7O
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THE STRUCTURE OF A DI-RIBOSOME (DISOME) AS A UNIT FOR RQC AND NGD QUALITY CONTROL PATHWAYS RECOGNITION.
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Tesina, P., Cheng, J., Becker, T., Beckmann, R.
Deposit date:2018-11-16
Release date:2019-01-16
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.
EMBO J., 38, 2019
6SNT
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YEAST 80S RIBOSOME STALLED ON SDD1 MRNA.
Descriptor:Saccharomyces cerevisiae S288C 18S ribosomal RNA (RDN18-1), rRNA, 40S ribosomal protein S0-A, ...
Authors:Tesina, P., Buschauer, R., Cheng, J., Becker, T., Beckmann, R.
Deposit date:2019-08-27
Release date:2020-03-04
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.
Nat.Struct.Mol.Biol., 27, 2020
6SV4
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THE CRYO-EM STRUCTURE OF SDD1-STALLED COLLIDED TRISOME.
Descriptor:25S rRNA, 5S rRNA, 5.8S rRNA, ...
Authors:Tesina, P., Buschauer, R., Cheng, J., Becker, T., Beckmann, R.
Deposit date:2019-09-17
Release date:2020-03-04
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.
Nat.Struct.Mol.Biol., 27, 2020
2MSR
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SOLUTION STRUCTURE OF LEDGF/P75 IBD IN COMPLEX WITH MLL1 PEPTIDE (140-160)
Descriptor:Histone-lysine N-methyltransferase 2A, PC4 and SFRS1-interacting protein
Authors:Cermakova, K., Tesina, P., Demeulemeester, J., El Ashkar, S., Mereau, H., Schwaller, J., Rezacova, P., Veverka, V., De Rijck, J.
Deposit date:2014-08-05
Release date:2014-08-20
Last modified:2014-10-08
Method:SOLUTION NMR
Cite:Validation and Structural Characterization of the LEDGF/p75-MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia.
Cancer Res., 74, 2014
6TB3
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YEAST 80S RIBOSOME IN COMPLEX WITH THE NOT5 SUBUNIT OF THE CCR4-NOT COMPLEX
Descriptor:Saccharomyces cerevisiae S288C 18S ribosomal RNA (RDN18-1), rRNA, mRNA, ...
Authors:Buschauer, R., Cheng, J., Berninghausen, O., Tesina, P., Becker, T., Beckmann, R.
Deposit date:2019-10-31
Release date:2020-04-22
Last modified:2020-04-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Science, 368, 2020
6TNU
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YEAST 80S RIBOSOME IN COMPLEX WITH EIF5A AND DECODING A-SITE AND P-SITE TRNAS.
Descriptor:18S rRNA, mRNA, 40S ribosomal protein S0-A, ...
Authors:Buschauer, R., Cheng, J., Berninghausen, O., Tesina, P., Becker, T., Beckmann, R.
Deposit date:2019-12-10
Release date:2020-04-22
Last modified:2020-04-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Science, 368, 2020
5YI9
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SOLUTION STRUCTURE OF THE LEDGF/P75 IBD - JPO2 (AA 56-91) COMPLEX
Descriptor:PC4 and SFRS1-interacting protein,Cell division cycle-associated 7-like protein
Authors:Veverka, V.
Deposit date:2017-10-03
Release date:2018-08-15
Method:SOLUTION NMR
Cite:Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EMO
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SOLUTION STRUCTURE OF THE LEDGF/P75 IBD - JPO2 (AA 1-32) COMPLEX
Descriptor:PC4 and SFRS1-interacting protein,LEDGF/p75 IBD-JPO2 M1
Authors:Veverka, V.
Deposit date:2017-10-03
Release date:2018-07-25
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EMP
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SOLUTION STRUCTURE OF THE LEDGF/P75 IBD - POGZ (AA 1370-1404) COMPLEX
Descriptor:PC4 and SFRS1-interacting protein,Pogo transposable element with ZNF domain
Authors:Veverka, V.
Deposit date:2017-10-03
Release date:2018-07-25
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EMQ
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SOLUTION STRUCTURE OF THE LEDGF/P75 IBD - MLL1 (AA 111-160) COMPLEX
Descriptor:PC4 and SFRS1-interacting protein,Histone-lysine N-methyltransferase 2A
Authors:Veverka, V.
Deposit date:2017-10-03
Release date:2018-08-01
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EMR
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SOLUTION STRUCTURE OF THE LEDGF/P75 IBD - IWS1 (AA 446-548) COMPLEX
Descriptor:PC4 and SFRS1-interacting protein,Protein IWS1 homolog
Authors:Veverka, V.
Deposit date:2017-10-03
Release date:2018-07-25
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5O2M
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P130CAS SH3 DOMAIN
Descriptor:Breast cancer anti-estrogen resistance 1
Authors:Hexnerova, R., Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2019-10-30
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5O2P
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P130CAS SH3 DOMAIN PTP-PEST PEPTIDE CHIMERA
Descriptor:Breast cancer anti-estrogen resistance 1,Tyrosine-protein phosphatase non-receptor type 12
Authors:Hexnerova, R., Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2019-10-30
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5O2Q
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P130CAS SH3 DOMAIN VINCULIN PEPTIDE CHIMERA
Descriptor:Breast cancer anti-estrogen resistance 1,Vinculin
Authors:Hexnerova, R., Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2019-10-30
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
6HD5
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CRYO-EM STRUCTURE OF THE RIBOSOME-NATA COMPLEX
Descriptor:N-terminal acetyltransferase A complex subunit NAT1, N-terminal acetyltransferase A complex catalytic subunit ARD1, N-alpha-acetyltransferase NAT5
Authors:Knorr, A.G., Becker, T., Beckmann, R.
Deposit date:2018-08-17
Release date:2018-12-19
Last modified:2019-01-16
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Ribosome-NatA architecture reveals that rRNA expansion segments coordinate N-terminal acetylation.
Nat. Struct. Mol. Biol., 26, 2019
6HD7
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CRYO-EM STRUCTURE OF THE RIBOSOME-NATA COMPLEX
Descriptor:Saccharomyces cerevisiae S288C 35S pre-ribosomal RNA (RDN37-1), miscRNA, 5S rRNA, ...
Authors:Knorr, A.G., Becker, T., Beckmann, R.
Deposit date:2018-08-17
Release date:2018-12-19
Last modified:2019-01-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Ribosome-NatA architecture reveals that rRNA expansion segments coordinate N-terminal acetylation.
Nat. Struct. Mol. Biol., 26, 2019
170172
PDB entries from 2020-10-21