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5KTH
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BU of 5kth by Molmil
Structure of cow mincle complexed with brartemicin
Descriptor: 2,4-dihydroxy-6-methyl Benzoic acid, CALCIUM ION, TRIETHYLENE GLYCOL, ...
Authors:Feinberg, H, Rambaruth, N.D.S, Jegouzo, S.A.F, Jacobsen, K.M, Djurhuus, R, Poulsen, T.B, Taylor, M.E, Drickamer, K, Weis, W.I.
Deposit date:2016-07-11
Release date:2016-08-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
J.Biol.Chem., 291, 2016
5KTI
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BU of 5kti by Molmil
Structure of cow mincle complexed with KMJ1
Descriptor: 2,3-dimethoxybenzoic acid, CALCIUM ION, TRIETHYLENE GLYCOL, ...
Authors:Feinberg, H, Rambaruth, N.D.S, Jegouzo, S.A.F, Jacobsen, K.M, Djurhuus, R, Poulsen, T.B, Taylor, M.E, Drickamer, K, Weis, W.I.
Deposit date:2016-07-11
Release date:2016-08-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
J.Biol.Chem., 291, 2016
4ZET
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BU of 4zet by Molmil
Blood dendritic cell antigen 2 (BDCA-2) complexed with GalGlcNAcMan
Descriptor: C-type lectin domain family 4 member C, CALCIUM ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose
Authors:Jegouzo, S.A.F, Feinberg, H, Dungarwalla, T, Drickamer, K, Weis, W.I, Taylor, M.E.
Deposit date:2015-04-20
Release date:2015-05-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2.
J.Biol.Chem., 290, 2015
4ZES
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BU of 4zes by Molmil
Blood dendritic cell antigen 2 (BDCA-2) complexed with methyl-mannoside
Descriptor: C-type lectin domain family 4 member C, CALCIUM ION, MAGNESIUM ION, ...
Authors:Jegouzo, S.A.F, Feinberg, H, Dungarwalla, T, Drickamer, K, Weis, W.I, Taylor, M.E.
Deposit date:2015-04-20
Release date:2015-05-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2.
J.Biol.Chem., 290, 2015
4ZRW
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BU of 4zrw by Molmil
Structure of cow mincle complexed with trehalose
Descriptor: CALCIUM ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, mincle protein
Authors:Feinberg, H, Rambaruth, N.D.S, Taylor, M.E, Drickamer, K, Weis, W.I.
Deposit date:2015-05-12
Release date:2016-05-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
J.Biol.Chem., 291, 2016
4ZRV
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BU of 4zrv by Molmil
Structure of cow mincle CRD complexed with trehalose mono butyrate
Descriptor: 6-O-butanoyl-alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
Authors:Feinberg, H, Rambaruth, N.D.S, Taylor, M.E, Drickamer, K, Weis, W.I.
Deposit date:2015-05-12
Release date:2016-05-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.095 Å)
Cite:Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
J.Biol.Chem., 291, 2016
4KZW
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BU of 4kzw by Molmil
Structure of the carbohydrate-recognition domain of the C-type lectin mincle
Descriptor: C-TYPE LECTIN MINCLE, CALCIUM ION, CITRATE ANION, ...
Authors:Feinberg, H, Jegouzo, S.A.F, Rowntree, T.J.W, Guan, Y, Brash, M.A, Taylor, M.E, Weis, W.I, Drickamer, K.
Deposit date:2013-05-30
Release date:2013-08-28
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mechanism for Recognition of an Unusual Mycobacterial Glycolipid by the Macrophage Receptor Mincle.
J.Biol.Chem., 288, 2013
4KZV
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BU of 4kzv by Molmil
Structure of the carbohydrate-recognition domain of the C-type lectin mincle bound to trehalose
Descriptor: C-type lectin mincle, CALCIUM ION, SODIUM ION, ...
Authors:Feinberg, H, Jegouzo, S.A.F, Rowntree, T.J.W, Guan, Y, Brash, M.A, Taylor, M.E, Weis, W.I, Drickamer, K.
Deposit date:2013-05-30
Release date:2013-08-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Mechanism for Recognition of an Unusual Mycobacterial Glycolipid by the Macrophage Receptor Mincle.
J.Biol.Chem., 288, 2013
4N34
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BU of 4n34 by Molmil
Structure of langerin CRD I313 with alpha-MeGlcNAc
Descriptor: C-type lectin domain family 4 member K, CALCIUM ION, methyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside
Authors:Feinberg, H, Rowntree, T.J.W, Tan, S.L.W, Drickamer, K, Weis, W.I, Taylor, M.E.
Deposit date:2013-10-06
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Common polymorphisms in human langerin change specificity for glycan ligands.
J.Biol.Chem., 288, 2013
4N37
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BU of 4n37 by Molmil
Structure of langerin CRD I313 D288 complexed with Me-Man
Descriptor: C-type lectin domain family 4 member K, CALCIUM ION, methyl alpha-D-mannopyranoside
Authors:Feinberg, H, Rowntree, T.J.W, Tan, S.L.W, Drickamer, K, Weis, W.I, Taylor, M.E.
Deposit date:2013-10-06
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Common polymorphisms in human langerin change specificity for glycan ligands.
J.Biol.Chem., 288, 2013
4N33
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BU of 4n33 by Molmil
Structure of langerin CRD complexed with GlcNAc-beta1-3Gal-beta1-4Glc-beta-CH2CH2N3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, C-type lectin domain family 4 member K, ...
Authors:Feinberg, H, Rowntree, T.J.W, Tan, S.L.W, Drickamer, K, Weis, W.I, Taylor, M.E.
Deposit date:2013-10-06
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Common polymorphisms in human langerin change specificity for glycan ligands.
J.Biol.Chem., 288, 2013
4N32
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BU of 4n32 by Molmil
Structure of langerin CRD with alpha-Me-GlcNAc.
Descriptor: C-type lectin domain family 4 member K, CALCIUM ION, methyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside
Authors:Feinberg, H, Rowntree, T.J.W, Tan, S.L.W, Drickamer, K, Weis, W.I, Taylor, M.E.
Deposit date:2013-10-06
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Common polymorphisms in human langerin change specificity for glycan ligands.
J.Biol.Chem., 288, 2013
4N38
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BU of 4n38 by Molmil
Structure of langerin CRD I313 D288 complexed with GlcNAc-beta1-3Gal-beta1-4GlcNAc-beta-CH2CH2N3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, C-type lectin domain family 4 member K, CALCIUM ION, ...
Authors:Feinberg, H, Rowntree, T.J.W, Tan, S.L.W, Drickamer, K, Weis, W.I, Taylor, M.E.
Deposit date:2013-10-06
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Common polymorphisms in human langerin change specificity for glycan ligands.
J.Biol.Chem., 288, 2013
4N36
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BU of 4n36 by Molmil
Structure of langerin CRD I313 D288 complexed with Me-GlcNAc
Descriptor: C-type lectin domain family 4 member K, CALCIUM ION, MAGNESIUM ION, ...
Authors:Feinberg, H, Rowntree, T.J.W, Tan, S.L.W, Drickamer, K, Weis, W.I, Taylor, M.E.
Deposit date:2013-10-06
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Common polymorphisms in human langerin change specificity for glycan ligands.
J.Biol.Chem., 288, 2013
4N35
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BU of 4n35 by Molmil
Structure of langerin CRD I313 complexed with GlcNAc-beta1-3Gal-beta1-4Glc-beta-CH2CH2N3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, C-type lectin domain family 4 member K, ...
Authors:Feinberg, H, Rowntree, T.J.W, Tan, S.L.W, Drickamer, K, Weis, W.I, Taylor, M.E.
Deposit date:2013-10-06
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Common polymorphisms in human langerin change specificity for glycan ligands.
J.Biol.Chem., 288, 2013
2OX9
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BU of 2ox9 by Molmil
Mouse Scavenger Receptor C-type Lectin carbohydrate-recognition domain.
Descriptor: CALCIUM ION, Collectin placenta 1, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Weis, W.I, Feinberg, H, Drickamer, K, Taylor, M.E.
Deposit date:2007-02-20
Release date:2007-04-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Scavenger receptor C-type lectin binds to the leukocyte cell surface glycan Lewis(x) by a novel mechanism.
J.Biol.Chem., 282, 2007
2OX8
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BU of 2ox8 by Molmil
Human Scavenger Receptor C-type Lectin carbohydrate-recognition domain.
Descriptor: CALCIUM ION, CHLORIDE ION, Scavenger receptor with C-type lectin type I, ...
Authors:Weis, W.I, Feinberg, H, Drickamer, K, Taylor, M.E.
Deposit date:2007-02-20
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Scavenger receptor C-type lectin binds to the leukocyte cell surface glycan Lewis(x) by a novel mechanism.
J.Biol.Chem., 282, 2007
3JQH
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BU of 3jqh by Molmil
Structure of the neck region of the glycan-binding receptor DC-SIGNR
Descriptor: C-type lectin domain family 4 member M
Authors:Feinberg, H, Tso, C.K.W, Taylor, M.E, Drickamer, K, Weis, W.I.
Deposit date:2009-09-06
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Segmented helical structure of the neck region of the glycan-binding receptor DC-SIGNR.
J.Mol.Biol., 394, 2009
3KQG
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BU of 3kqg by Molmil
Trimeric Structure of Langerin
Descriptor: C-type lectin domain family 4 member K, CALCIUM ION
Authors:Feinberg, H, Powlesland, A.S, Taylor, M.E, Weis, W.I.
Deposit date:2009-11-17
Release date:2010-02-23
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Trimeric structure of langerin.
J.Biol.Chem., 285, 2010
1EGI
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BU of 1egi by Molmil
STRUCTURE OF A C-TYPE CARBOHYDRATE-RECOGNITION DOMAIN (CRD-4) FROM THE MACROPHAGE MANNOSE RECEPTOR
Descriptor: CALCIUM ION, MACROPHAGE MANNOSE RECEPTOR
Authors:Feinberg, H, Park-Snyder, S, Kolatkar, A.R, Heise, C.T, Taylor, M.E, Weis, W.I.
Deposit date:2000-02-15
Release date:2000-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor.
J.Biol.Chem., 275, 2000
1EGG
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BU of 1egg by Molmil
STRUCTURE OF A C-TYPE CARBOHYDRATE-RECOGNITION DOMAIN (CRD-4) FROM THE MACROPHAGE MANNOSE RECEPTOR
Descriptor: CALCIUM ION, MACROPHAGE MANNOSE RECEPTOR
Authors:Feinberg, H, Park-Snyder, S, Kolatkar, A.R, Heise, C.T, Taylor, M.E, Weis, W.I.
Deposit date:2000-02-15
Release date:2000-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor.
J.Biol.Chem., 275, 2000
1SL5
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BU of 1sl5 by Molmil
Crystal Structure of DC-SIGN carbohydrate recognition domain complexed with LNFP III (Dextra L504).
Descriptor: CALCIUM ION, MAGNESIUM ION, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ...
Authors:Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K.
Deposit date:2004-03-05
Release date:2004-06-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
1SL4
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BU of 1sl4 by Molmil
Crystal Structure of DC-SIGN carbohydrate recognition domain complexed with Man4
Descriptor: CALCIUM ION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, mDC-SIGN1B type I isoform
Authors:Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K.
Deposit date:2004-03-05
Release date:2004-06-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
1SL6
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BU of 1sl6 by Molmil
Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x.
Descriptor: C-type lectin DC-SIGNR, CALCIUM ION, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose
Authors:Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K.
Deposit date:2004-03-05
Release date:2004-06-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
3P5F
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BU of 3p5f by Molmil
Structure of the carbohydrate-recognition domain of human Langerin with man2 (Man alpha1-2 Man)
Descriptor: C-type lectin domain family 4 member K, CALCIUM ION, alpha-D-mannopyranose, ...
Authors:Feinberg, H, Taylor, M.E, Razi, N, McBride, R, Knirel, Y.A, Graham, S.A, Drickamer, K, Weis, W.I.
Deposit date:2010-10-08
Release date:2010-12-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.7501 Å)
Cite:Structural Basis for Langerin Recognition of Diverse Pathogen and Mammalian Glycans through a Single Binding Site.
J.Mol.Biol., 405, 2011

 

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