Author results

7JIR
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THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2 , C111S MUTANT, IN COMPLEX WITH PLP_SNYDER457
Descriptor:Papain-like protease, 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, ZINC ION, ...
Authors:Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-07-23
Release date:2020-08-05
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant, in complex with PLP_Snyder457
to be published
7JIT
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THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2 , C111S MUTANT, IN COMPLEX WITH PLP_SNYDER495
Descriptor:Papain-like protease, 5-[(carbamoylcarbamoyl)amino]-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide, ZINC ION, ...
Authors:Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-07-23
Release date:2020-08-05
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant, in complex with PLP_Snyder495
to be published
7JIV
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THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2 , C111S MUTANT, IN COMPLEX WITH PLP_SNYDER530
Descriptor:Papain-like protease, 5-(acryloylamino)-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide, ZINC ION, ...
Authors:Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-07-23
Release date:2020-08-05
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant, in complex with PLP_Snyder530
to be published
7JIW
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THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2 IN COMPLEX WITH PLP_SNYDER530
Descriptor:Papain-Like Protease, 5-(acryloylamino)-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide, ZINC ION, ...
Authors:Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-07-23
Release date:2020-08-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of Papain-Like Protease of SARS CoV-2 in complex with PLP_Snyder530
to be published
7JN2
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THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2 IN COMPLEX WITH PLP_SNYDER441
Descriptor:Papain-Like Protease, 3-amino-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide, ZINC ION, ...
Authors:Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-08-03
Release date:2020-08-12
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:The crystal structure of Papain-Like Protease of SARS CoV-2 in complex with PLP_Snyder441
to be published
7KOJ
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THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2, C111S MUTANT, IN COMPLEX WITH PLP_SNYDER494
Descriptor:Papain-like protease, 2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]-5-{[(prop-2-en-1-yl)carbamoyl]amino}benzamide, ZINC ION, ...
Authors:Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-11-09
Release date:2020-11-18
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with PLP_Snyder494
to be published
7KOK
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THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2, C111S MUTANT, IN COMPLEX WITH PLP_SNYDER496
Descriptor:Papain-like protease, 5-[(E)-(hydroxyimino)methyl]-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide, ZINC ION, ...
Authors:Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-11-09
Release date:2020-11-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with PLP_Snyder496
to be published
7KOL
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THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2 IN COMPLEX WITH PLP_SNYDER496
Descriptor:Papain-Like Protease, 5-[(E)-(hydroxyimino)methyl]-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide, ZINC ION, ...
Authors:Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-11-09
Release date:2020-11-18
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:The crystal structure of Papain-Like Protease of SARS CoV-2 in complex with PLP_Snyder496
to be published
7KRX
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THE CRYSTAL STRUCTURE OF PAPAIN-LIKE PROTEASE OF SARS COV-2, C111S MUTANT, IN COMPLEX WITH PLP_SNYDER441
Descriptor:Papain-like protease, 3-amino-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide, ZINC ION, ...
Authors:Osipiuk, J., Tesar, C., Endres, M., Lisnyak, V., Maki, S., Taylor, C., Zhang, Y., Zhou, Z., Azizi, S.A., Jones, K., Kathayat, R., Snyder, S.A., Dickinson, B.C., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-11-20
Release date:2020-12-02
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with PLP_Snyder441
to be published
4F3L
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CRYSTAL STRUCTURE OF THE HETERODIMERIC CLOCK:BMAL1 TRANSCRIPTIONAL ACTIVATOR COMPLEX
Descriptor:BMAL1b, Circadian locomoter output cycles protein kaput
Authors:Huang, N., Chelliah, Y., Shan, Y., Taylor, C., Yoo, S., Partch, C., Green, C.B., Zhang, H., Takahashi, J.
Deposit date:2012-05-09
Release date:2012-06-06
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.268 Å)
Cite:Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex.
Science, 337, 2012
5MKV
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CRYSTAL STRUCTURE OF HUMAN DIHYDROPYRIMIDINEASE-LIKE 2 (DPYSL2A)/COLLAPSIN RESPONSE MEDIATOR PROTEIN (CRMP2) RESIDUES 13-516
Descriptor:Dihydropyrimidinase-related protein 2, 1,2-ETHANEDIOL
Authors:Sethi, R., Zheng, Y., Krojer, T., Velupillai, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Ahmed, A.A., von Delft, F.
Deposit date:2016-12-05
Release date:2017-02-22
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Nat Commun, 9, 2018
5MLE
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CRYSTAL STRUCTURE OF HUMAN DIHYDROPYRIMIDINEASE-LIKE 2 (DPYSL2A)/COLLAPSIN RESPONSE MEDIATOR PROTEIN (CRMP2 13-516) MUTANT Y479E/Y499E
Descriptor:Dihydropyrimidinase-related protein 2, DI(HYDROXYETHYL)ETHER, 1,2-ETHANEDIOL, ...
Authors:Sethi, R., Zheng, Y., Talon, R., Velupillai, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Ahmed, A.A., von Delft, F.
Deposit date:2016-12-06
Release date:2017-02-22
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Nat Commun, 9, 2018
5N5L
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CRYSTAL STRUCTURE OF HUMAN PIM-1 KINASE IN COMPLEX WITH A CONSENSUSPEPTIDE AND [2-OXO-2-(1H-PYRROL-2-YL)ETHYL] 5-BROMO-1H-INDOLE-3-CARBOXYLATE
Descriptor:Serine/threonine-protein kinase pim-1, Pimtide, 5-bromanyl-1~{H}-indole-3-carboxylic acid, ...
Authors:Siefker, C., Heine, A., Klebe, G.
Deposit date:2017-02-14
Release date:2018-03-07
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:A crystallographic fragment study with human Pim-1 kinase
to be published
5N5M
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CRYSTAL STRUCTURE OF HUMAN PIM-1 KINASE IN COMPLEX WITH A CONSENSUSPEPTIDE AND (R)-3-(2-((ISOQUINOLIN-5-YLMETHYL)(METHYL)CARBAMOYL)PHENYL)PYRROLIDIN-1-IUM
Descriptor:Serine/threonine-protein kinase pim-1, Pimtide, ~{N}-(isoquinolin-5-ylmethyl)-~{N}-methyl-2-[(3~{R})-pyrrolidin-3-yl]benzamide
Authors:Siefker, C., Heine, A., Klebe, G.
Deposit date:2017-02-14
Release date:2018-03-07
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:A crystallographic fragment study with human Pim-1 kinase
to be published
3P2B
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CRYSTAL STRUCTURE OF PI3K GAMMA WITH 3-(2-MORPHOLINO-6-(PYRIDIN-3-YLAMINO)PYRIMIDIN-4-YL)PHENOL
Descriptor:Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, 3-[2-morpholin-4-yl-6-(pyridin-3-ylamino)pyrimidin-4-yl]phenol
Authors:Knapp, M.S., Elling, R.A., Ornelas, E.
Deposit date:2010-10-01
Release date:2011-08-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Identification and structure-activity relationship of 2-morpholino 6-(3-hydroxyphenyl) pyrimidines, a class of potent and selective PI3 kinase inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
5NAF
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CO-CRYSTAL STRUCTURE OF AN MECP2 PEPTIDE WITH TBLR1 WD40 DOMAIN
Descriptor:F-box-like/WD repeat-containing protein TBL1XR1, Methyl-CpG-binding protein 2, GLYCEROL
Authors:Kruusvee, V., Cook, A.G.
Deposit date:2017-02-27
Release date:2017-03-29
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.493 Å)
Cite:Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6YND
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GAPDH PURIFIED FROM THE SUPERNATANT OF HEK293F CELLS: CRYSTAL FORM 1 OF 4.
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL
Authors:Roversi, P., Lia, A.
Deposit date:2020-04-13
Release date:2020-05-06
Last modified:2020-10-14
Method:X-RAY DIFFRACTION (1.525 Å)
Cite:Partial catalytic Cys oxidation of human GAPDH to Cys-sulfonic acid.
Wellcome Open Res, 5, 2020
6YNE
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GAPDH PURIFIED FROM THE SUPERNATANT OF HEK293F CELLS: CRYSTAL FORM 2 OF 4.
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL
Authors:Roversi, P., Lia, A.
Deposit date:2020-04-13
Release date:2020-05-06
Last modified:2020-10-14
Method:X-RAY DIFFRACTION (1.853 Å)
Cite:Partial catalytic Cys oxidation of human GAPDH to Cys-sulfonic acid.
Wellcome Open Res, 5, 2020
6YNF
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GAPDH PURIFIED FROM THE SUPERNATANT OF HEK293F CELLS: CRYSTAL FORM 3 OF 4.
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL
Authors:Roversi, P., Lia, A.
Deposit date:2020-04-13
Release date:2020-05-06
Last modified:2020-10-14
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Partial catalytic Cys oxidation of human GAPDH to Cys-sulfonic acid.
Wellcome Open Res, 5, 2020
6YNH
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GAPDH PURIFIED FROM THE SUPERNATANT OF HEK293F CELLS: CRYSTAL FORM 4 OF 4
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL
Authors:Roversi, P., Lia, A.
Deposit date:2020-04-13
Release date:2020-05-06
Last modified:2020-10-14
Method:X-RAY DIFFRACTION (2.621 Å)
Cite:Partial catalytic Cys oxidation of human GAPDH to Cys-sulfonic acid.
Wellcome Open Res, 5, 2020
171916
PDB entries from 2020-12-02