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6QN1
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T=4 QUASI-SYMMETRIC BACTERIAL MICROCOMPARTMENT PARTICLE
Descriptor:Carbon dioxide concentrating mechanism protein CcmL, BMC domain-containing protein
Authors:Kalnins, G.
Deposit date:2019-02-08
Release date:2019-12-25
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Encapsulation mechanisms and structural studies of GRM2 bacterial microcompartment particles
To Be Published
6HPN
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CRYSTAL STRUCTURE OF BORRELIA SPIELMANII WP_012665240 (BSA64) - AN ORTHOLOGOUS PROTEIN TO B. BURGDORFERI BBA64
Descriptor:Antigen, P35
Authors:Brangulis, K., Akopjana, I., Kazaks, A., Tars, K.
Deposit date:2018-09-21
Release date:2019-10-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural analysis of the outer surface proteins from Borrelia burgdorferi
To Be Published
6R1G
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CRYSTAL STRUCTURE OF BORRELIA BURGDORFERI PERIPLASMIC PROTEIN BB0365 (IPLA7, P22)
Descriptor:Outer surface 22 kDa lipoprotein, ZINC ION, TRIETHYLENE GLYCOL, ...
Authors:Brangulis, K., Akopjana, I., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2019-03-14
Release date:2019-09-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural analysis of Borrelia burgdorferi periplasmic lipoprotein BB0365 involved in Lyme disease infection.
Febs Lett., 2019
6RJW
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF LYME DISEASE AGENT BORRELIA BURGDORFERI MAJOR VIRULENCE FACTOR BB0323 (SE-MET DATA)
Descriptor:LysM domain protein
Authors:Brangulis, K., Akopjana, I., Kazaks, A., Tars, K.
Deposit date:2019-04-29
Release date:2019-09-11
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of the N-terminal domain of the major virulence factor BB0323 from the Lyme disease agent Borrelia burgdorferi.
Acta Crystallogr D Struct Biol, 75, 2019
6RJX
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF LYME DISEASE AGENT BORRELIA BURGDORFERI MAJOR VIRULENCE FACTOR BB0323 (NATIVE DATA)
Descriptor:LysM domain protein
Authors:Brangulis, K., Akopjana, I., Kazaks, A., Tars, K.
Deposit date:2019-04-29
Release date:2019-09-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the N-terminal domain of the major virulence factor BB0323 from the Lyme disease agent Borrelia burgdorferi.
Acta Crystallogr D Struct Biol, 75, 2019
6QO1
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CRYSTAL STRUCTURE OF BORRELIA (BORRELIELLA) BURGDORFERI OUTER SURFACE PROTEIN BBA69
Descriptor:Putative surface protein
Authors:Brangulis, K., Akopjana, I., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2019-02-12
Release date:2019-06-26
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of Borrelia burgdorferi outer surface protein BBA69 in comparison to the paralogous protein CspA.
Ticks Tick Borne Dis, 10, 2019
6ROC
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CRYSTAL STRUCTURE OF BORRELIA BURGDORFERI OUTER SURFACE PROTEIN BBA69, MUTANT LEU214MET (SE-MET DATA)
Descriptor:Putative surface protein
Authors:Brangulis, K., Akopjana, I., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2019-05-11
Release date:2019-06-26
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of Borrelia burgdorferi outer surface protein BBA69 in comparison to the paralogous protein CspA.
Ticks Tick Borne Dis, 10, 2019
6FZE
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BBE31 FROM LYME DISEASE AGENT BORRELIA (BORRELIELLA) BURGDORFERI PLAYING A VITAL ROLE IN SUCCESSFUL COLONIZATION OF THE MAMMALIAN HOST (NATIVE DATA)
Descriptor:Putative surface protein, GLUTATHIONE, SULFATE ION
Authors:Brangulis, K., Akopjana, I., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2018-03-14
Release date:2019-03-27
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the ability to bind glutathione.
Biochim Biophys Acta Gen Subj, 1864, 2019
6FZZ
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CRYSTAL STRUCTURE OF BSE31 (BSPA14S_RS05060 GENE PRODUCT) FROM LYME DISEASE AGENT BORRELIA (BORRELIELLA) SPIELMANII
Descriptor:Virulent strain associated lipoprotein, TETRAETHYLENE GLYCOL
Authors:Brangulis, K., Akopjana, I., Kazaks, A., Tars, K.
Deposit date:2018-03-15
Release date:2019-03-27
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the ability to bind glutathione.
Biochim Biophys Acta Gen Subj, 1864, 2019
6FXE
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BBE31 FROM LYME DISEASE AGENT BORRELIA (BORRELIELLA) BURGDORFERI PLAYING A VITAL ROLE IN SUCCESSFUL COLONIZATION OF THE MAMMALIAN HOST
Descriptor:Putative surface protein, GLUTATHIONE
Authors:Brangulis, K., Akopjana, I., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2018-03-08
Release date:2019-03-20
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the ability to bind glutathione.
Biochim Biophys Acta Gen Subj, 1864, 2019
6GOL
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THREE DIMENSIONAL STRUCTURE OF A NOVEL INFLUENZA HEMAGGLUTININ TRI-STALK PROTEIN
Descriptor:Hemagglutinin tri-stalk
Authors:Kirsteina, A., Kazaks, A., Tars, K.
Deposit date:2018-06-01
Release date:2018-10-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and applications of novel influenza HA tri-stalk protein for evaluation of HA stem-specific immunity.
PLoS ONE, 13, 2018
6FL0
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CRYSTAL STRUCTURE OF THE MEMBRANE ATTACK COMPLEX ASSEMBLY INHIBITOR BGA71 FROM LYME DISEASE AGENT BORRELIELLA BAVARIENSIS
Descriptor:membrane attack complex assembly inhibitor BGA71
Authors:Brangulis, K., Akopjana, I., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2018-01-25
Release date:2018-08-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the membrane attack complex assembly inhibitor BGA71 from the Lyme disease agent Borrelia bavariensis.
Sci Rep, 8, 2018
6FMH
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CRYSTAL STRUCTURE OF THE MEMBRANE ATTACK COMPLEX ASSEMBLY INHIBITOR BGA71 FROM LYME DISEASE AGENT BORRELIELLA BAVARIENSIS (NATIVE DATA)
Descriptor:membrane attack complex assembly inhibitor BGA71
Authors:Brangulis, K., Akopjana, I., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2018-01-31
Release date:2018-08-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the membrane attack complex assembly inhibitor BGA71 from the Lyme disease agent Borrelia bavariensis.
Sci Rep, 8, 2018
6FE0
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THREE DIMENSIONAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE IX IN COMPLEX WITH BENZENESULFONAMIDE.
Descriptor:Carbonic anhydrase 9, ZINC ION, 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide
Authors:Leitans, J., Tars, K.
Deposit date:2017-12-28
Release date:2018-07-04
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
Oncotarget, 9, 2018
6FE1
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THREE DIMENSIONAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE IX IN COMPLEX WITH BENZENESULFONAMIDE.
Descriptor:Carbonic anhydrase 9, ZINC ION, 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide
Authors:Leitans, J., Tars, K.
Deposit date:2017-12-28
Release date:2018-07-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
Oncotarget, 9, 2018
6FE2
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THREE DIMENSIONAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE IX
Descriptor:Carbonic anhydrase 9, ZINC ION
Authors:Leitans, J., Tars, K.
Deposit date:2017-12-28
Release date:2018-07-04
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
Oncotarget, 9, 2018
6G98
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THREE DIMENSIONAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE IX IN COMPLEX WITH SULFONAMIDE
Descriptor:Carbonic anhydrase 9, ZINC ION, 4-[2-[3-(cyclododecylamino)-2,5,6-tris(fluoranyl)-4-sulfamoyl-phenyl]sulfanylethyl]benzoic acid
Authors:Leitans, J., Tars, K.
Deposit date:2018-04-10
Release date:2018-07-04
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
Oncotarget, 9, 2018
6G9U
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THREE DIMENSIONAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE IX IN COMPLEX WITH SULFONAMIDE
Descriptor:Carbonic anhydrase 9, ZINC ION, 4-[2-[3-(cyclooctylamino)-2,5,6-tris(fluoranyl)-4-sulfamoyl-phenyl]sulfanylethyl]benzoic acid
Authors:Leitans, J., Tars, K.
Deposit date:2018-04-11
Release date:2018-07-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
Oncotarget, 9, 2018
5MJN
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THREE DIMENSIONAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 5-[(4CHLOROBENZYL)SULFANYL]THIOPHENE-2-SULFONAMIDE
Descriptor:Carbonic anhydrase 2, ZINC ION, 5-[(4-chlorophenyl)methylsulfanyl]thiophene-2-sulfonamide
Authors:Leitans, J., Tars, K.
Deposit date:2016-12-01
Release date:2017-12-06
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations.
Bioorg. Med. Chem., 25, 2017
5ODJ
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SINGLE-STRANDED DNA-BINDING PROTEIN FROM BACTERIOPHAGE ENC34
Descriptor:Single-stranded DNA-binding protein, MAGNESIUM ION, CHLORIDE ION
Authors:Cernooka, E., Rumnieks, J., Kazaks, A., Tars, K.
Deposit date:2017-07-05
Release date:2017-10-25
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis for DNA Recognition of a Single-stranded DNA-binding Protein from Enterobacter Phage Enc34.
Sci Rep, 7, 2017
5ODK
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SINGLE-STRANDED DNA-BINDING PROTEIN FROM BACTERIOPHAGE ENC34, C-TERMINAL TRUNCATION
Descriptor:single-stranded DNA-binding protein, PHOSPHATE ION, GLYCEROL
Authors:Cernooka, E., Rumnieks, J., Kazaks, A., Tars, K.
Deposit date:2017-07-05
Release date:2017-10-25
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Structural Basis for DNA Recognition of a Single-stranded DNA-binding Protein from Enterobacter Phage Enc34.
Sci Rep, 7, 2017
5ODL
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SINGLE-STRANDED DNA-BINDING PROTEIN FROM BACTERIOPHAGE ENC34 IN COMPLEX WITH SSDNA
Descriptor:single-stranded DNA-binding protein, oligo(T), GLYCEROL, ...
Authors:Cernooka, E., Rumnieks, J., Kazaks, A., Tars, K.
Deposit date:2017-07-05
Release date:2017-10-25
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural Basis for DNA Recognition of a Single-stranded DNA-binding Protein from Enterobacter Phage Enc34.
Sci Rep, 7, 2017
5T87
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CRYSTAL STRUCTURE OF CDI COMPLEX FROM CUPRIAVIDUS TAIWANENSIS LMG 19424
Descriptor:CdiI immunity protein, CdiA toxin
Authors:Michalska, K., Joachimiak, G., Jedrzejczak, R., Hayes, C.S., Goulding, C.W., Joachimiak, A., Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG)
Deposit date:2016-09-06
Release date:2017-09-13
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).
Proteins, 86 Suppl 1, 2018
5MNT
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BACTERIOPHAGE QBETA MATURATION PROTEIN
Descriptor:A2 maturation protein
Authors:Rumnieks, J., Tars, K.
Deposit date:2016-12-13
Release date:2017-01-11
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Crystal Structure of the Maturation Protein from Bacteriophage Q beta.
J. Mol. Biol., 429, 2017
5LQP
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CRYO-EM RECONSTRUCTION OF BACTERIOPHAGE AP205 VIRUS-LIKE PARTICLES.
Descriptor:Coat protein
Authors:Diebolder, C.A., Rumnieks, J., Tars, K., Koning, R.I.
Deposit date:2016-08-17
Release date:2016-12-14
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of AP205 Coat Protein Reveals Circular Permutation in ssRNA Bacteriophages.
J. Mol. Biol., 428, 2016