Author results

1H4L
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STRUCTURE AND REGULATION OF THE CDK5-P25(NCK5A) COMPLEX
Descriptor:CELL DIVISION PROTEIN KINASE 5, CYCLIN-DEPENDENT KINASE 5 ACTIVATOR
Authors:Tarricone, C., Dhavan, R., Peng, J., Areces, L.B., Tsai, L.-H., Musacchio, A.
Deposit date:2001-05-11
Release date:2002-08-14
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure and Regulation of the Cdk5-P25(Nck5A) Complex
Mol.Cell, 8, 2001
1I49
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CRYSTAL STRUCTURE ANALYSIS OF ARFAPTIN
Descriptor:ARFAPTIN 2
Authors:Tarricone, C., Xiao, B., Justin, N., Gamblin, S.J., Smerdon, S.J.
Deposit date:2001-02-20
Release date:2001-05-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Nature, 411, 2001
1I4D
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CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP COMPLEXED WITH ARFAPTIN (P21)
Descriptor:ARFAPTIN 2, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, MAGNESIUM ION, ...
Authors:Tarricone, C., Xiao, B., Justin, N., Gamblin, S.J., Smerdon, S.J.
Deposit date:2001-02-20
Release date:2001-05-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Nature, 411, 2001
1I4L
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CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP IN COMPLEX WITH ARFAPTIN (P41)
Descriptor:ARFAPTIN 2, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, MAGNESIUM ION, ...
Authors:Tarricone, C., Xiao, B., Justin, N., Gamblin, S.J., Smerdon, S.J.
Deposit date:2001-02-22
Release date:2001-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Nature, 411, 2001
1I4T
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CRYSTAL STRUCTURE ANALYSIS OF RAC1-GMPPNP IN COMPLEX WITH ARFAPTIN
Descriptor:ARFAPTIN 2, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, MAGNESIUM ION, ...
Authors:Tarricone, C., Xiao, B., Justin, N., Gamblin, S.J., Smerdon, S.J.
Deposit date:2001-02-23
Release date:2001-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Nature, 411, 2001
1VHB
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BACTERIAL DIMERIC HEMOGLOBIN FROM VITREOSCILLA STERCORARIA
Descriptor:HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Tarricone, C., Galizzi, A., Coda, A., Ascenzi, P., Bolognesi, M.
Deposit date:1997-02-19
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Unusual structure of the oxygen-binding site in the dimeric bacterial hemoglobin from Vitreoscilla sp.
Structure, 5, 1997
1VYH
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PAF-AH HOLOENZYME: LIS1/ALFA2
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB BETA SUBUNIT, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB ALPHA SUBUNIT
Authors:Tarricone, C., Perrina, F., Monzani, S., Massimiliano, L., Knapp, S., Tsai, L.-H., Derewenda, Z.S., Musacchio, A.
Deposit date:2004-04-30
Release date:2005-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Coupling Paf Signaling to Dynein Regulation: Structure of Lis1 in Complex with Paf-Acetylhydrolase.
Neuron, 44, 2004
2VHB
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AZIDE ADDUCT OF THE BACTERIAL HEMOGLOBIN FROM VITREOSCILLA STERCORARIA
Descriptor:HEMOGLOBIN, AZIDE ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Tarricone, C., Galizzi, A., Coda, A., Ascenzi, P., Bolognesi, M.
Deposit date:1997-02-19
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Unusual structure of the oxygen-binding site in the dimeric bacterial hemoglobin from Vitreoscilla sp.
Structure, 5, 1997
2V66
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CRYSTAL STRUCTURE OF THE COILED-COIL DOMAIN OF NDEL1 (A.A. 58 TO 169) C
Descriptor:NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1, MERCURY (II) ION
Authors:Tarricone, C., Perrina, F., Musacchio, A.
Deposit date:2007-07-13
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure of the Coiled-Coil Domain of Ndel1 and the Basis of its Interaction with Lis1, the Causal Protein of Miller-Dieker Lissencephaly.
Structure, 15, 2007
1AE8
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HUMAN ALPHA-THROMBIN INHIBITION BY EOC-D-PHE-PRO-AZALYS-ONP
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUGEN, ...
Authors:De Simone, G., Balliano, G., Milla, P., Gallina, C., Giordano, C., Tarricone, C., Rizzi, M., Bolognesi, M., Ascenzi, P.
Deposit date:1997-03-06
Release date:1997-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study.
J.Mol.Biol., 269, 1997
1AFE
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HUMAN ALPHA-THROMBIN INHIBITION BY CBZ-PRO-AZALYS-ONP
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUGEN, ...
Authors:De Simone, G., Balliano, G., Milla, P., Gallina, C., Giordano, C., Tarricone, C., Rizzi, M., Bolognesi, M., Ascenzi, P.
Deposit date:1997-03-06
Release date:1997-12-03
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study.
J.Mol.Biol., 269, 1997
2BFX
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MECHANISM OF AURORA-B ACTIVATION BY INCENP AND INHIBITION BY HESPERADIN.
Descriptor:AURORA KINASE B-A, INNER CENTROMERE PROTEIN A
Authors:Sessa, F., Mapelli, M., Ciferri, C., Tarricone, C., Areces, L.B., Schneider, T.R., Stukenberg, P.T., Musacchio, A.
Deposit date:2004-12-15
Release date:2005-05-03
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanism of Aurora B Activation by Incenp and Inhibition by Hesperadin
Mol.Cell, 18, 2005
2BFY
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COMPLEX OF AURORA-B WITH INCENP AND HESPERADIN.
Descriptor:AURORA KINASE B-A, INNER CENTROMERE PROTEIN A, N-[2-OXO-3-((E)-PHENYL{[4-(PIPERIDIN-1-YLMETHYL)PHENYL]IMINO}METHYL)-2,6-DIHYDRO-1H-INDOL-5-YL]ETHANESULFONAMIDE
Authors:Sessa, F., Mapelli, M., Ciferri, C., Tarricone, C., Areces, L.B., Schneider, T.R., Stukenberg, P.T., Musacchio, A.
Deposit date:2004-12-15
Release date:2005-05-03
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanism of Aurora B Activation by Incenp and Inhibition by Hesperadin
Mol.Cell, 18, 2005
1LHS
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LOGGERHEAD SEA TURTLE MYOGLOBIN (AQUO-MET)
Descriptor:MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Nardini, M., Tarricone, C., Lania, A., Desideri, A., De Sanctis, G., Coletta, M., Petruzzelli, R., Ascenzi, P., Coda, A., Bolognesi, M.
Deposit date:1995-02-01
Release date:1995-06-03
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Reptile heme protein structure: X-ray crystallographic study of the aquo-met and cyano-met derivatives of the loggerhead sea turtle (Caretta caretta) myoglobin at 2.0 A resolution.
J.Mol.Biol., 247, 1995
1LHT
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LOGGERHEAD SEA TURTLE MYOGLOBIN (CYANO-MET)
Descriptor:MYOGLOBIN, CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Nardini, M., Tarricone, C., Lania, A., Desideri, A., De Sanctis, G., Coletta, M., Petruzzelli, R., Ascenzi, P., Coda, A., Bolognesi, M.
Deposit date:1995-02-01
Release date:1995-06-03
Last modified:2017-02-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Reptile heme protein structure: X-ray crystallographic study of the aquo-met and cyano-met derivatives of the loggerhead sea turtle (Caretta caretta) myoglobin at 2.0 A resolution.
J.Mol.Biol., 247, 1995
3VHB
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IMIDAZOLE ADDUCT OF THE BACTERIAL HEMOGLOBIN FROM VITREOSCILLA SP.
Descriptor:PROTEIN (HEMOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE, IMIDAZOLE
Authors:Bolognesi, M., Boffi, A., Coletta, M., Mozzarelli, A., Pesce, A., Tarricone, C., Ascenzi, P.
Deposit date:1999-03-17
Release date:1999-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Anticooperative ligand binding properties of recombinant ferric Vitreoscilla homodimeric hemoglobin: a thermodynamic, kinetic and X-ray crystallographic study.
J.Mol.Biol., 291, 1999
4VHB
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THIOCYANATE ADDUCT OF THE BACTERIAL HEMOGLOBIN FROM VITREOSCILLA SP.
Descriptor:PROTEIN (HEMOGLOBIN), THIOCYANATE ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bolognesi, M., Boffi, A., Coletta, M., Mozzarelli, A., Pesce, A., Tarricone, C., Ascenzi, P.
Deposit date:1999-03-11
Release date:1999-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Anticooperative ligand binding properties of recombinant ferric Vitreoscilla homodimeric hemoglobin: a thermodynamic, kinetic and X-ray crystallographic study.
J.Mol.Biol., 291, 1999
1UV5
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GLYCOGEN SYNTHASE KINASE 3 BETA COMPLEXED WITH 6-BROMOINDIRUBIN-3'-OXIME
Descriptor:GLYCOGEN SYNTHASE KINASE-3 BETA, 6-BROMOINDIRUBIN-3'-OXIME, PHOSPHATE ION, ...
Authors:Dajani, R., Pearl, L.H., Roe, S.M.
Deposit date:2004-01-14
Release date:2004-01-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Gsk-3-Selective Inhibitors Derived from Tyrian Purple Indurubins
Chem.Biol., 10, 2003
2V71
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COILED-COIL REGION OF NUDEL
Descriptor:NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1
Authors:Derewenda, U., Cooper, D.R., Kim, M.H., Derewenda, Z.S.
Deposit date:2007-07-25
Release date:2007-11-27
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:The Structure of the Coiled-Coil Domain of Ndel1 and the Basis of its Interaction with Lis1, the Causal Protein of Miller-Dieker Lissencephaly.
Structure, 15, 2007
5HYN
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STRUCTURE OF HUMAN POLYCOMB REPRESSIVE COMPLEX 2 (PRC2) WITH ONCOGENIC HISTONE H3K27M PEPTIDE
Descriptor:Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, Polycomb protein SUZ12, ...
Authors:Zhang, Y., Justin, N., Wilson, J.R., Gamblin, S.J.
Deposit date:2016-02-01
Release date:2016-05-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Nat Commun, 7, 2016