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1OJI
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ANATOMY OF GLYCOSYNTHESIS: STRUCTURE AND KINETICS OF THE HUMICOLA INSOLENS CEL7B E197A AND E197S GLYCOSYNTHASE MUTANTS
Descriptor:ENDOGLUCANASE I, N-ACETYL-D-GLUCOSAMINE, GLYCEROL
Authors:Ducros, V.M.-A., Tarling, C.A., Zechel, D.L., Brzozowski, A.M., Frandsen, T.P., Von Ossowski, I., Schulein, M., Withers, S.G., Davies, G.J.
Deposit date:2003-07-10
Release date:2004-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola Insolens Cel7B E197A and E197S Glycosynthase Mutants
Chem.Biol., 10, 2003
1OJJ
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ANATOMY OF GLYCOSYNTHESIS: STRUCTURE AND KINETICS OF THE HUMICOLA INSOLENS CEL7BE197A AND E197S GLYCOSYNTHASE MUTANTS
Descriptor:ENDOGLUCANASE I, BETA-D-GLUCOSE, BETA-D-GALACTOSE, ...
Authors:Ducros, V.M.-A., Tarling, C.A., Zechel, D.L., Brzozowski, A.M., Frandsen, T.P., Von Ossowski, I., Schulein, M., Withers, S.G., Davies, G.J.
Deposit date:2003-07-10
Release date:2004-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola Insolens Cel7B E197A and E197S Glycosynthase Mutants
Chem.Biol., 10, 2003
1OJK
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ANATOMY OF GLYCOSYNTHESIS: STRUCTURE AND KINETICS OF THE HUMICOLA INSOLENS CEL7BE197A AND E197S GLYCOSYNTHASE MUTANTS
Descriptor:ENDOGLUCANASE I, ALPHA-D-GLUCOSE, BETA-D-GLUCOSE, ...
Authors:Ducros, V.M.-A., Tarling, C.A., Zechel, D.L., Brzozowski, A.M., Frandsen, T.P., Von Ossowski, I., Schulein, M., Withers, S.G., Davies, G.J.
Deposit date:2003-07-10
Release date:2004-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola Insolens Cel7B E197A and E197S Glycosynthase Mutants
Chem.Biol., 10, 2003
1UQT
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TREHALOSE-6-PHOSPHATE FROM E. COLI BOUND WITH UDP-2-FLUORO GLUCOSE.
Descriptor:ALPHA, ALPHA-TREHALOSE-PHOSPHATE SYNTHASE, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE
Authors:Gibson, R.P., Tarling, C.A., Roberts, S., Withers, S.G., Davies, G.J.
Deposit date:2003-10-20
Release date:2003-12-12
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:The donor subsite of trehalose-6-phosphate synthase: binary complexes with UDP-glucose and UDP-2-deoxy-2-fluoro-glucose at 2 A resolution.
J. Biol. Chem., 279, 2004
1UQU
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TREHALOSE-6-PHOSPHATE FROM E. COLI BOUND WITH UDP-GLUCOSE.
Descriptor:ALPHA, ALPHA-TREHALOSE-PHOSPHATE SYNTHASE, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Gibson, R.P., Tarling, C.A., Roberts, S., Withers, S.G., Davies, G.J.
Deposit date:2003-10-20
Release date:2003-11-13
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:The donor subsite of trehalose-6-phosphate synthase: binary complexes with UDP-glucose and UDP-2-deoxy-2-fluoro-glucose at 2 A resolution.
J. Biol. Chem., 279, 2004
1V0K
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XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 5.8
Descriptor:ENDO-1,4-BETA-XYLANASE A, BETA-D-XYLOPYRANOSE, PIPERIDINE-3,4,5-TRIOL
Authors:Gloster, T.M., Williams, S.J., Roberts, S., Tarling, C.A., Wicki S, J., Withers, G., Davies, G.J.
Deposit date:2004-03-31
Release date:2004-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:Atomic Resolution Analyses of the Binding of Xylobiose-Derived Deoxynojirimycin and Isofagomine to Xylanase Xyn10A
Chem.Commun.(Camb.), 16, 2004
1V0L
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XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-ISOFAGOMINE AT PH 5.8
Descriptor:ENDO-1,4-BETA-XYLANASE A, PIPERIDINE-3,4-DIOL, BETA-D-XYLOPYRANOSE
Authors:Gloster, T.M., Williams, S.J., Roberts, S., Tarling, C.A., Wicki, J., Withers, S.G., Davies, G.J.
Deposit date:2004-03-31
Release date:2004-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Atomic Resolution Analyses of the Binding of Xylobiose-Derived Deoxynojirimycin and Isofagomine to Xylanase Xyn10A
Chem.Commun.(Camb.), 16, 2004
1V0M
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XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 7.5
Descriptor:ENDO-1,4-BETA-XYLANASE A, PIPERIDINE-3,4,5-TRIOL, BETA-D-XYLOPYRANOSE, ...
Authors:Gloster, T.M., Williams, S.J., Roberts, S., Tarling, C.A., Wicki, J., Withers, S.G., Davies, G.J.
Deposit date:2004-03-31
Release date:2004-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Atomic Resolution Analyses of the Binding of Xylobiose-Derived Deoxynojirimycin and Isofagomine to Xylanase Xyn10A
Chem.Commun.(Camb.), 16, 2004
1V0N
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XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-ISOFAGOMINE AT PH 7.5
Descriptor:ENDO-1,4-BETA-XYLANASE A, 1,2-ETHANEDIOL, PIPERIDINE-3,4-DIOL, ...
Authors:Gloster, T.M., Williams, S.J., Roberts, S., Tarling, C.A., Wicki, J., Withers, S.G., Davies, G.J.
Deposit date:2004-03-31
Release date:2004-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic Resolution Analyses of the Binding of Xylobiose-Derived Deoxynojirimycin and Isofagomine to Xylanase Xyn10A
Chem.Commun.(Camb.), 16, 2004
1W3J
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FAMILY 1 B-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH TETRAHYDROOXAZINE
Descriptor:BETA-GLUCOSIDASE, TETRAHYDROOXAZINE
Authors:Gloster, T.M., Macdonald, J.M., Tarling, C.A., Stick, R.V., Withers, S.W., Davies, G.J.
Deposit date:2004-07-16
Release date:2004-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural, Thermodynamic, and Kinetic Analyses of Tetrahydrooxazine-Derived Inhibitors Bound to {Beta}-Glucosidases
J.Biol.Chem., 279, 2004
1W3K
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ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS IN COMPLEX WITH CELLOBIO DERIVED-TETRAHYDROOXAZINE
Descriptor:ENDOGLUCANASE 5A, BETA-D-GLUCOSE, TETRAHYDROOXAZINE, ...
Authors:Gloster, T.M., Macdonald, J.M., Tarling, C.A., Stick, R.V., Withers, S.W., Davies, G.J.
Deposit date:2004-07-16
Release date:2004-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural, Thermodynamic, and Kinetic Analyses of Tetrahydrooxazine-Derived Inhibitors Bound to {Beta}-Glucosidases
J.Biol.Chem., 279, 2004
1W3L
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ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS IN COMPLEX WITH CELLOTRI DERIVED-TETRAHYDROOXAZINE
Descriptor:ENDOGLUCANASE 5A, GLYCEROL, SULFATE ION, ...
Authors:Gloster, T.M., Macdonald, J.M., Tarling, C.A., Stick, R.V., Withers, S.W., Davies, G.J.
Deposit date:2004-07-16
Release date:2004-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Structural, Thermodynamic, and Kinetic Analyses of Tetrahydrooxazine-Derived Inhibitors Bound to {Beta}-Glucosidases
J.Biol.Chem., 279, 2004
2C1X
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STRUCTURE AND ACTIVITY OF A FLAVONOID 3-O GLUCOSYLTRANSFERASE REVEALS THE BASIS FOR PLANT NATURAL PRODUCT MODIFICATION
Descriptor:UDP-GLUCOSE FLAVONOID 3-O GLYCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Offen, W., Martinez-Fleites, C., Kiat-Lim, E., Yang, M., Davis, B.G., Tarling, C.A., Ford, C.M., Bowles, D.J., Davies, G.J.
Deposit date:2005-09-22
Release date:2006-01-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification.
Embo J., 25, 2006
2C1Z
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STRUCTURE AND ACTIVITY OF A FLAVONOID 3-O GLUCOSYLTRANSFERASE REVEALS THE BASIS FOR PLANT NATURAL PRODUCT MODIFICATION
Descriptor:UDP-GLUCOSE FLAVONOID 3-O GLYCOSYLTRANSFERASE, 3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE
Authors:Offen, W., Martinez-Fleites, C., Kiat-Lim, E., Yang, M., Davis, B.G., Tarling, C.A., Ford, C.M., Bowles, D.J., Davies, G.J.
Deposit date:2005-09-22
Release date:2006-01-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification.
Embo J., 25, 2006
2C9Z
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STRUCTURE AND ACTIVITY OF A FLAVONOID 3-0 GLUCOSYLTRANSFERASE REVEALS THE BASIS FOR PLANT NATURAL PRODUCT MODIFICATION
Descriptor:UDP GLUCOSE\:FLAVONOID 3-O-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, 3,5,7,3',4'-PENTAHYDROXYFLAVONE
Authors:Offen, W., Martinez-Fleites, C., Kiat-Lim, E., Yang, M., Davis, B.G., Tarling, C.A., Ford, C.M., Bowles, D.J., Davies, G.J.
Deposit date:2005-12-15
Release date:2006-01-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification.
Embo J., 25, 2006
2V38
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FAMILY 5 ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS IN COMPLEX WITH CELLOBIO-DERIVED NOEUROMYCIN
Descriptor:ENDOGLUCANASE 5A, GLYCEROL, SULFATE ION, ...
Authors:Gloster, T.M., Meloncelli, P.J., Money, V.A., Tarling, C.A., Davies, G.J., Withers, S.G., Stick, R.V.
Deposit date:2007-06-13
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:D-Glucosylated Derivatives of Isofagomine and Noeuromycin and Their Potential as Inhibitors of Beta-Glycoside Hydrolases
To be Published
2V3G
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STRUCTURE OF A FAMILY 26 LICHENASE IN COMPLEX WITH NOEUROMYCIN
Descriptor:ENDOGLUCANASE H, BETA-D-GLUCOSE, (2R,3S,4R,5R)-5-(HYDROXYMETHYL)PIPERIDINE-2,3,4-TRIOL
Authors:Meloncelli, P.J., Gloster, T.M., Money, V.A., Tarling, C.A., Davies, G.J., Withers, S.G., Stick, R.V.
Deposit date:2007-06-18
Release date:2007-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:D-Glucosylated Derivatives of Isofagomine and Noeuromycin and Their Potential as Inhibitors of Beta-Glycoside Hydrolases
To be Published
2WK2
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CHITINASE A FROM SERRATIA MARCESCENS ATCC990 IN COMPLEX WITH CHITOTRIO-THIAZOLINE DITHIOAMIDE.
Descriptor:CHITINASE A, 2-deoxy-2-(ethanethioylamino)-beta-D-glucopyranose, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, ...
Authors:Taylor, E.J., Dennis, R.J., Macdonald, J.M., Tarling, C.A., Knapp, S., Withers, S.G., Davies, G.J.
Deposit date:2009-06-04
Release date:2010-03-16
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Chitinase Inhibition by Chitobiose and Chitotriose Thiazolines.
Angew.Chem.Int.Ed.Engl., 49, 2010
2WLY
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CHITINASE A FROM SERRATIA MARCESCENS ATCC990 IN COMPLEX WITH CHITOTRIO-THIAZOLINE.
Descriptor:Chitinase, 1,4-DIETHYLENE DIOXIDE, DI(HYDROXYETHYL)ETHER, ...
Authors:Taylor, E.J., Dennis, R.J., Macdonald, J.M., Tarling, C.A., Knapp, S., Withers, S.G., Davies, G.J.
Deposit date:2009-06-29
Release date:2010-03-16
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Chitinase inhibition by chitobiose and chitotriose thiazolines.
Angew. Chem. Int. Ed. Engl., 49, 2010
2WLZ
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CHITINASE A FROM SERRATIA MARCESCENS ATCC990 IN COMPLEX WITH CHITOBIO- THIAZOLINE.
Descriptor:CHITINASE A, 1,4-DIETHYLENE DIOXIDE, DI(HYDROXYETHYL)ETHER, ...
Authors:Taylor, E.J., Dennis, R.J., Macdonald, J.M., Tarling, C.A., Knapp, S., Withers, S.G., Davies, G.J.
Deposit date:2009-06-29
Release date:2010-03-16
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Chitinase Inhibition by Chitobiose and Chitotriose Thiazolines.
Angew.Chem.Int.Ed.Engl., 49, 2010
2WM0
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CHITINASE A FROM SERRATIA MARCESCENS ATCC990 IN COMPLEX WITH CHITOBIO- THIAZOLINE THIOAMIDE.
Descriptor:CHITINASE A, N-ACETYL-D-GLUCOSAMINE, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, ...
Authors:Taylor, E.J., Dennis, R.J., Macdonald, J.M., Tarling, C.A., Knapp, S., Withers, S.G., Davies, G.J.
Deposit date:2009-06-29
Release date:2010-03-16
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Chitinase Inhibition by Chitobiose and Chitotriose Thiazolines.
Angew.Chem.Int.Ed.Engl., 49, 2010
3D4Y
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GOLGI MANNOSIDASE II COMPLEX WITH MANNOIMIDAZOLE
Descriptor:Alpha-mannosidase 2, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Kuntz, D.A., Tarling, C.A., Withers, S.G., Rose, D.R.
Deposit date:2008-05-15
Release date:2008-08-05
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen.
Biochemistry, 47, 2008
3D4Z
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GOLGI MANNOSIDASE II COMPLEX WITH GLUCO-IMIDAZOLE
Descriptor:Alpha-mannosidase 2, ZINC ION, (4R)-2-METHYLPENTANE-2,4-DIOL, ...
Authors:Kuntz, D.A., Tarling, C.A., Withers, S.G., Rose, D.R.
Deposit date:2008-05-15
Release date:2008-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen.
Biochemistry, 47, 2008
3D50
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GOLGI MANNOSIDASE II COMPLEX WITH N-OCTYL-6-EPI-VALIENAMINE
Descriptor:Alpha-mannosidase 2, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Kuntz, D.A., Tarling, C.A., Withers, S.G., Rose, D.R.
Deposit date:2008-05-15
Release date:2008-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen.
Biochemistry, 47, 2008
3D51
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GOLGI MANNOSIDASE II COMPLEX WITH GLUCO-HYDROXYIMINOLACTAM
Descriptor:Alpha-mannosidase 2, ZINC ION, (4R)-2-METHYLPENTANE-2,4-DIOL, ...
Authors:Kuntz, D.A., Tarling, C.A., Withers, S.G., Rose, D.R.
Deposit date:2008-05-15
Release date:2008-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen.
Biochemistry, 47, 2008
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