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3ZV8
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CRYSTAL STRUCTURE OF 3C PROTEASE OF ENTEROVIRUS 68
Descriptor:3C PROTEASE
Authors:Tan, J., Perbandt, M., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-07-24
Release date:2012-08-08
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
3ZV9
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3C PROTEASE OF ENTEROVIRUS 68 COMPLEXED WITH MICHAEL RECEPTOR INHIBITOR 74
Descriptor:3C PROTEASE, ETHYL (4R)-4-[(TERT-BUTOXYCARBONYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE
Authors:Tan, J., Perbandt, M., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-07-24
Release date:2012-08-08
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
3ZVA
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3C PROTEASE OF ENTEROVIRUS 68 COMPLEXED WITH MICHAEL RECEPTOR INHIBITOR 75
Descriptor:3C PROTEASE, ETHYL (4R)-4-({N-[(BENZYLOXY)CARBONYL]-L-PHENYLALANYL}AMINO)-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE
Authors:Tan, J., Perbandt, M., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-07-24
Release date:2012-08-08
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
3ZVB
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3C PROTEASE OF ENTEROVIRUS 68 COMPLEXED WITH MICHAEL RECEPTOR INHIBITOR 81
Descriptor:3C PROTEASE, ETHYL (4R)-4-{[N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANYL]AMINO}-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE
Authors:Tan, J., Perbandt, M., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-07-24
Release date:2012-08-08
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
3ZVC
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3C PROTEASE OF ENTEROVIRUS 68 COMPLEXED WITH MICHAEL RECEPTOR INHIBITOR 82
Descriptor:3C PROTEASE, ETHYL (5S,8S,11R)-8-BENZYL-5-(3-TERT-BUTOXY-3-OXOPROPYL)-3,6,9-TRIOXO-11-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}-1-PHENYL-2-OXA-4,7,10-TRIAZATETRADECAN-14-OATE
Authors:Tan, J., Perbandt, M., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-07-24
Release date:2012-08-08
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
3ZVD
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3C PROTEASE OF ENTEROVIRUS 68 COMPLEXED WITH MICHAEL RECEPTOR INHIBITOR 83
Descriptor:3C PROTEASE, ETHYL (5S,8S,11R)-8-BENZYL-5-(2-TERT-BUTOXY-2-OXOETHYL)-3,6,9-TRIOXO-11-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}-1-PHENYL-2-OXA-4,7,10-TRIAZATETRADECAN-14-OATE
Authors:Tan, J., Perbandt, M., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-07-24
Release date:2012-08-08
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
3ZVE
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3C PROTEASE OF ENTEROVIRUS 68 COMPLEXED WITH MICHAEL RECEPTOR INHIBITOR 84
Descriptor:3C PROTEASE, O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonyl-N-{(2R)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-phenylalaninamide
Authors:Tan, J., Perbandt, M., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-07-24
Release date:2012-08-08
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
3ZVF
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3C PROTEASE OF ENTEROVIRUS 68 COMPLEXED WITH MICHAEL RECEPTOR INHIBITOR 85
Descriptor:3C PROTEASE, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-seryl-N-{(2R)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-phenylalaninamide
Authors:Tan, J., Perbandt, M., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-07-24
Release date:2012-08-08
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
3ZVG
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3C PROTEASE OF ENTEROVIRUS 68 COMPLEXED WITH MICHAEL RECEPTOR INHIBITOR 98
Descriptor:3C PROTEASE, N-(tert-butoxycarbonyl)-O-tert-butyl-L-threonyl-N-{(2R)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-phenylalaninamide
Authors:Tan, J., Perbandt, M., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-07-24
Release date:2012-08-08
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
2W2G
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HUMAN SARS CORONAVIRUS UNIQUE DOMAIN
Descriptor:NON-STRUCTURAL PROTEIN 3, SULFATE ION
Authors:Tan, J., Vonrhein, C., Smart, O.S., Bricogne, G., Bollati, M., Kusov, Y., Hansen, G., Mesters, J.R., Schmidt, C.L., Hilgenfeld, R.
Deposit date:2008-10-30
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:The Sars-Unique Domain (Sud) of Sars Coronavirus Contains Two Macrodomains that Bind G-Quadruplexes.
Plos Pathog., 5, 2009
2WCT
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HUMAN SARS CORONAVIRUS UNIQUE DOMAIN (TRICLINIC FORM)
Descriptor:NON-STRUCTURAL PROTEIN 3
Authors:Tan, J., Vonrhein, C., Smart, O.S., Bricogne, G., Bollati, M., Hansen, G., Mesters, J.R., Hilgenfeld, R.
Deposit date:2009-03-16
Release date:2009-05-26
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:The Sars-Unique Domain (Sud) of Sars Coronavirus Contains Two Macrodomains that Bind G-Quadruplexes.
Plos Pathog., 5, 2009
3ZYD
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CRYSTAL STRUCTURE OF 3C PROTEASE OF COXSACKIEVIRUS B3
Descriptor:3C PROTEINASE, GLYCEROL
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-22
Release date:2012-08-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Peptidic Ab-Nonsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZYE
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CRYSTAL STRUCTURE OF 3C PROTEASE MUTANT (T68A) OF COXSACKIEVIRUS B3
Descriptor:3C PROTEINASE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-22
Release date:2012-08-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZ3
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CRYSTAL STRUCTURE OF 3C PROTEASE MUTANT (N126Y) OF COXSACKIEVIRUS B3
Descriptor:3C PROTEINASE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZ4
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CRYSTAL STRUCTURE OF 3C PROTEASE MUTANT (T68A AND N126Y) OF COXSACKIEVIRUS B3
Descriptor:3C PROTEINASE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZ5
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CRYSTAL STRUCTURE OF 3C PROTEASE OF COXSACKIEVIRUS B3 COMPLEXED WITH ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR 74
Descriptor:3C PROTEINASE, ETHYL (4R)-4-[(TERT-BUTOXYCARBONYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZ6
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CRYSTAL STRUCTURE OF 3C PROTEASE OF COXSACKIEVIRUS B3 COMPLEXED WITH MICHAEL RECEPTOR INHIBITOR 75
Descriptor:POLYPROTEIN 3BCD, ETHYL (4R)-4-({N-[(BENZYLOXY)CARBONYL]-L-PHENYLALANYL}AMINO)-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Peptidic Ab-Nonsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZ7
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CRYSTAL STRUCTURE OF 3C PROTEASE OF COXSACKIEVIRUS B3 COMPLEXED WITH ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR 81
Descriptor:3C PROTEINASE, ETHYL (4R)-4-{[N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANYL]AMINO}-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZ8
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CRYSTAL STRUCTURE OF 3C PROTEASE OF COXSACKIEVIRUS B3 COMPLEXED WITH ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR 82
Descriptor:3C PROTEINASE, ETHYL (5S,8S,11R)-8-BENZYL-5-(3-TERT-BUTOXY-3-OXOPROPYL)-3,6,9-TRIOXO-11-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}-1-PHENYL-2-OXA-4,7,10-TRIAZATETRADECAN-14-OATE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZ9
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CRYSTAL STRUCTURE OF 3C PROTEASE OF COXSACKIEVIRUS B3 COMPLEXED WITH ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR 83
Descriptor:3C PROTEINASE, ETHYL (5S,8S,11R)-8-BENZYL-5-(2-TERT-BUTOXY-2-OXOETHYL)-3,6,9-TRIOXO-11-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}-1-PHENYL-2-OXA-4,7,10-TRIAZATETRADECAN-14-OATE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZA
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CRYSTAL STRUCTURE OF 3C PROTEASE OF COXSACKIEVIRUS B3 COMPLEXED WITH ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR 84
Descriptor:3C PROTEINASE, O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonyl-N-{(2R)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-phenylalaninamide
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZB
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CRYSTAL STRUCTURE OF 3C PROTEASE OF COXSACKIEVIRUS B3 COMPLEXED WITH ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR 85
Descriptor:3C PROTEINASE, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-seryl-N-{(2R)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-phenylalaninamide
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZC
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CRYSTAL STRUCTURE OF 3C PROTEASE MUTANT (T68A AND N126Y) OF COXSACKIEVIRUS B3 COMPLEXED WITH ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR 83
Descriptor:3C PROTEINASE, ETHYL (5S,8S,11R)-8-BENZYL-5-(2-TERT-BUTOXY-2-OXOETHYL)-3,6,9-TRIOXO-11-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}-1-PHENYL-2-OXA-4,7,10-TRIAZATETRADECAN-14-OATE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZD
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CRYSTAL STRUCTURE OF 3C PROTEASE MUTANT (T68A AND N126Y) OF COXSACKIEVIRUS B3 COMPLEXED WITH ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR 85
Descriptor:3C PROTEINASE, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-seryl-N-{(2R)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-phenylalaninamide
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
4AFK
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IN MESO STRUCTURE OF ALGINATE TRANSPORTER, ALGE, FROM PSEUDOMONAS AERUGINOSA, PAO1
Descriptor:ALGINATE PRODUCTION PROTEIN ALGE, CALCIUM ION, CITRATE ANION, ...
Authors:Tan, J., Pye, V.E., Aragao, D., Caffrey, M.
Deposit date:2012-01-19
Release date:2013-02-06
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
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