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6OBI
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BU of 6obi by Molmil
Remarkable rigidity of the single alpha-helical domain of myosin-VI revealed by NMR spectroscopy
Descriptor: Myosin-VI
Authors:Barnes, A, Shen, Y, Ying, J, Takagi, Y, Torchia, D.A, Sellers, J, Bax, A.
Deposit date:2019-03-20
Release date:2019-06-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Remarkable Rigidity of the Single alpha-Helical Domain of Myosin-VI As Revealed by NMR Spectroscopy.
J.Am.Chem.Soc., 141, 2019
2PW6
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BU of 2pw6 by Molmil
Crystal structure of uncharacterized protein JW3007 from Escherichia coli K12
Descriptor: Uncharacterized protein ygiD, ZINC ION
Authors:Newton, M.G, Takagi, Y, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokayama, S, Li, Y, Chen, L, Zhu, J, Ruble, J, Liu, Z.J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-10
Release date:2007-06-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of uncharacterized protein JW3007 from Escherichia coli K12.
To be Published
7ROZ
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BU of 7roz by Molmil
Structure of RNA-dependent RNA polymerase 2 (RDR2) from Arabidopsis thaliana
Descriptor: MAGNESIUM ION, RNA-dependent RNA polymerase 2
Authors:Fukudome, A, Pikaard, C.S, Takagi, Y.
Deposit date:2021-08-02
Release date:2021-12-08
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure and RNA template requirements of Arabidopsis RNA-DEPENDENT RNA POLYMERASE 2.
Proc.Natl.Acad.Sci.USA, 118, 2021
7RQS
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BU of 7rqs by Molmil
Arabidopsis RNA-dependent RNA polymerase 2
Descriptor: MAGNESIUM ION, RNA-dependent RNA polymerase 2
Authors:Fukudome, A, Pikaard, C.S, Takagi, Y.
Deposit date:2021-08-07
Release date:2021-12-08
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Structure and RNA template requirements of Arabidopsis RNA-DEPENDENT RNA POLYMERASE 2.
Proc.Natl.Acad.Sci.USA, 118, 2021
6GQ3
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BU of 6gq3 by Molmil
Human asparagine synthetase (ASNS) in complex with 6-diazo-5-oxo-L-norleucine (DON) at 1.85 A resolution
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-OXO-L-NORLEUCINE, ...
Authors:Zhu, W, Radadiya, A, Bisson, C, Jin, Y, Nordin, B.E, Imasaki, T, Wenzel, S, Sedelnikova, S.E, Berry, A.H, Nomanbhoy, T.K, Kozarich, J.W, Takagi, Y, Rice, D.W, Richards, N.G.J.
Deposit date:2018-06-07
Release date:2019-09-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity.
Commun Biol, 2, 2019
4YTL
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BU of 4ytl by Molmil
Structure of the KOW2-KOW3 Domain of Transcription Elongation Factor Spt5.
Descriptor: GLYCEROL, SULFATE ION, Transcription elongation factor SPT5
Authors:Meyer, P.A, Li, S, ZHang, M, Yamada, K, Takagi, Y, Hartzog, G.A, Fu, J.
Deposit date:2015-03-17
Release date:2015-08-12
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structures and Functions of the Multiple KOW Domains of Transcription Elongation Factor Spt5.
Mol.Cell.Biol., 35, 2015
4YTK
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BU of 4ytk by Molmil
Structure of the KOW1-Linker1 domain of Transcription Elongation Factor Spt5
Descriptor: Transcription elongation factor SPT5
Authors:Meyer, P.A, Li, S, Zhang, M, Yamada, K, Takagi, Y, Hartzog, G.A, Fu, J.
Deposit date:2015-03-17
Release date:2015-08-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.0904 Å)
Cite:Structures and Functions of the Multiple KOW Domains of Transcription Elongation Factor Spt5.
Mol.Cell.Biol., 35, 2015
3RJ1
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BU of 3rj1 by Molmil
Architecture of the Mediator Head module
Descriptor: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ...
Authors:Imasaki, T, Calero, G, Cai, G, Tsai, K.L, Yamada, K, Cardelli, F, Erdjument-Bromage, H, Tempst, P, Berger, I, Kornberg, G.L, Asturias, F.J, Kornberg, R.D, Takagi, Y.
Deposit date:2011-04-14
Release date:2011-07-27
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Architecture of the Mediator head module.
Nature, 475, 2011
6L7V
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BU of 6l7v by Molmil
Crystal structure of Cet1 from Trypanosoma cruzi in complex with tripolyphosphate, manganese and iodide ions.
Descriptor: IODIDE ION, MANGANESE (II) ION, TRIPHOSPHATE, ...
Authors:Kuwabara, N, Ho, K.
Deposit date:2019-11-03
Release date:2020-06-03
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the RNA triphosphatase fromTrypanosoma cruziprovide insights into how it recognizes the 5'-end of the RNA substrate.
J.Biol.Chem., 295, 2020
6L7X
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BU of 6l7x by Molmil
Crystal structure of Cet1 from Trypanosoma cruzi in complex with #951 ligand
Descriptor: 1,3-dimethyl-7-propyl-purine-2,6-dione, SULFATE ION, mRNA_triPase domain-containing protein
Authors:Kuwabara, N, Ho, K.
Deposit date:2019-11-03
Release date:2020-06-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Crystal structures of the RNA triphosphatase fromTrypanosoma cruziprovide insights into how it recognizes the 5'-end of the RNA substrate.
J.Biol.Chem., 295, 2020
6L7W
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BU of 6l7w by Molmil
Crystal structure of Cet1 from Trypanosoma cruzi in complex with manganese ion.
Descriptor: MANGANESE (II) ION, mRNA_triPase domain-containing protein
Authors:Kuwabara, N, Ho, K.
Deposit date:2019-11-03
Release date:2020-06-03
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the RNA triphosphatase fromTrypanosoma cruziprovide insights into how it recognizes the 5'-end of the RNA substrate.
J.Biol.Chem., 295, 2020
6L7Y
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BU of 6l7y by Molmil
Crystal structure of Cet1 from Trypanosoma cruzi in complex with #466 ligand.
Descriptor: 3,4,6,7-tetrahydroacridine-1,8(2H,5H)-dione, SULFATE ION, mRNA_triPase domain-containing protein
Authors:Kuwabara, N, Ho, K.
Deposit date:2019-11-03
Release date:2020-06-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal structures of the RNA triphosphatase fromTrypanosoma cruziprovide insights into how it recognizes the 5'-end of the RNA substrate.
J.Biol.Chem., 295, 2020
6XAF
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BU of 6xaf by Molmil
1.9A crystal structure of the GTPase domain of Parkinson's disease-associated protein LRRK2 carrying R1398H
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
Authors:Hoang, Q.Q, Liao, J, Huang, X, Park, Y, Wu, C.X.
Deposit date:2020-06-04
Release date:2021-06-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.968 Å)
Cite:Structural basis for conformational plasticity in the GTPase domain of the Parkinson's disease-associated protein LRRK2
To be Published
6SWT
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BU of 6swt by Molmil
Affimer9 co-crystalised with the CH domains of alpha actinin 2.
Descriptor: Affimer 9, Alpha-actinin-2
Authors:Peckham, M, Trinh, C.H, Rogers, B.
Deposit date:2019-09-23
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Nanoscale Pattern Extraction from Relative Positions of Sparse 3D Localizations.
Nano Lett., 21, 2021
5WU4
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BU of 5wu4 by Molmil
Crystal structure of human Tut1 bound with MgATP, form II
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Yamashita, S, Tomita, K.
Deposit date:2016-12-16
Release date:2017-05-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of U6 snRNA-specific terminal uridylyltransferase
Nat Commun, 8, 2017
3L85
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BU of 3l85 by Molmil
Crystal structure of human NUDT5 complexed with 8-oxo-dGMP
Descriptor: 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, ADP-sugar pyrophosphatase
Authors:Arimori, T, Yamagata, Y.
Deposit date:2009-12-29
Release date:2011-01-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Diverse substrate recognition and hydrolysis mechanisms of human NUDT5
Nucleic Acids Res., 39, 2011
7F2X
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BU of 7f2x by Molmil
Crystal structure of MEK1 C121S mutant
Descriptor: MEK1 F11, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Fujioka, Y, Noda, N.N.
Deposit date:2021-06-15
Release date:2022-06-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.007 Å)
Cite:Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
Nat Commun, 13, 2022
3J1O
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BU of 3j1o by Molmil
Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module
Descriptor: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ...
Authors:Asturias, F.J, Imasaki, T.
Deposit date:2012-03-29
Release date:2013-03-06
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Interaction of the mediator head module with RNA polymerase II.
Structure, 20, 2012
3J1N
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BU of 3j1n by Molmil
Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module
Descriptor: DNA-directed RNA polymerase II subunit RPABC1, DNA-directed RNA polymerase II subunit RPABC2, DNA-directed RNA polymerase II subunit RPABC3, ...
Authors:Asturias, F.J, Imasaki, T.
Deposit date:2012-03-29
Release date:2013-03-06
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Interaction of the mediator head module with RNA polymerase II.
Structure, 20, 2012
3ACA
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BU of 3aca by Molmil
Crystal structure of human NUDT5 complexed with 8-oxo-dADP and manganese
Descriptor: 8-oxo-7,8-dihydro-2'-deoxy-adenosine-5'-diphosphate, ADP-sugar pyrophosphatase, MANGANESE (II) ION
Authors:Arimori, T, Yamagata, Y.
Deposit date:2009-12-30
Release date:2011-01-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Diverse substrate recognition and hydrolysis mechanisms of human NUDT5
Nucleic Acids Res., 39, 2011
3AC9
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BU of 3ac9 by Molmil
Crystal structure of human NUDT5 complexed with 8-oxo-dGDP and manganese
Descriptor: 2'-deoxy-8-oxoguanosine 5'-(trihydrogen diphosphate), ADP-sugar pyrophosphatase, MANGANESE (II) ION
Authors:Arimori, T, Yamagata, Y.
Deposit date:2009-12-30
Release date:2011-01-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Diverse substrate recognition and hydrolysis mechanisms of human NUDT5
Nucleic Acids Res., 39, 2011
3OLR
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BU of 3olr by Molmil
PTPN22 in complex with consensus phospho-tyrosine peptide 1
Descriptor: SKAP2, Tyrosine-protein phosphatase non-receptor type 22
Authors:Yu, X, Sun, J.-P, Zhang, S, Zhang, Z.-Y.
Deposit date:2010-08-26
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure basis of LYP substrate specificity revealed by reverse alanine screening and crystallography
To be Published
3OMH
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BU of 3omh by Molmil
Crystal structure of PTPN22 in complex with SKAP-HOM pTyr75 peptide
Descriptor: Src kinase-associated phosphoprotein 2, Tyrosine-protein phosphatase non-receptor type 22
Authors:Yu, X, Sun, J.-P, Zhang, S, Zhang, Z.-Y.
Deposit date:2010-08-26
Release date:2011-06-29
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Substrate Specificity of Lymphoid-specific Tyrosine Phosphatase (Lyp) and Identification of Src Kinase-associated Protein of 55 kDa Homolog (SKAP-HOM) as a Lyp Substrate.
J.Biol.Chem., 286, 2011
6OJF
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BU of 6ojf by Molmil
Dimeric structure of LRRK2 GTPase domain
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
Authors:Hoang, Q.Q, Wu, C.X, Liao, J, Park, Y.
Deposit date:2019-04-11
Release date:2020-10-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for conformational plasticity in the GTPase domain of the Parkinson's disease-associated protein LRRK2
To be published
6OJE
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BU of 6oje by Molmil
Dimeric structure of LRRK2 GTPase domain
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
Authors:Hoang, Q.Q, Wu, C.X, Liao, J, Park, Y.
Deposit date:2019-04-11
Release date:2020-10-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for conformational plasticity in the GTPase domain of the Parkinson's disease-associated protein LRRK2
To Be Published

 

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