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1NPE
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BU of 1npe by Molmil
Crystal structure of Nidogen/Laminin Complex
Descriptor: CADMIUM ION, Laminin gamma-1 chain, nidogen
Authors:Takagi, J, Yang, Y.T, Liu, J.-H, Wang, J.-H, Springer, T.A.
Deposit date:2003-01-17
Release date:2003-08-12
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complex between nidogen and laminin fragments reveals a paradigmatic beta-propeller interface
Nature, 424, 2003
8JYR
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BU of 8jyr by Molmil
Crystal structure of anti-HER2 antibody H2Mab-119 in complex with HER2 domain I
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H2Mab-119 VH-CH1, H2Mab-119 light chain, ...
Authors:Arimori, T, Takagi, J.
Deposit date:2023-07-03
Release date:2024-03-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies.
Structure, 2024
8JYQ
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BU of 8jyq by Molmil
Crystal structure of cancer-specific anti-HER2 antibody H2Mab-214 in complex with epitope peptide
Descriptor: H2CasMab-1 VH(S112C),SARAH, H2CasMab-1 VL,SARAH(S37C), H2CasMab-1 epitope peptide
Authors:Arimori, T, Takagi, J.
Deposit date:2023-07-03
Release date:2024-03-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies.
Structure, 2024
7NWL
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BU of 7nwl by Molmil
Cryo-EM structure of human integrin alpha5beta1 (open form) in complex with fibronectin and TS2/16 Fv-clasp
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-5, ...
Authors:Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N.
Deposit date:2021-03-17
Release date:2021-06-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand.
Sci Adv, 7, 2021
7NXD
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BU of 7nxd by Molmil
Cryo-EM structure of human integrin alpha5beta1 in the half-bent conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N.
Deposit date:2021-03-18
Release date:2021-08-25
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand.
Sci Adv, 7, 2021
5GKR
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BU of 5gkr by Molmil
Crystal structure of SLE patient-derived anti-DNA antibody in complex with oligonucleotide
Descriptor: DNA (5'-D(P*TP*TP*TP*T)-3'), IgG2, Fab (heavy chain), ...
Authors:Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J.
Deposit date:2016-07-05
Release date:2017-07-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus
Sci Rep, 7, 2017
5GKS
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BU of 5gks by Molmil
Crystal structure of SLE patient-derived anti-DNA antibody
Descriptor: IgG2, Fab (heavy chain), PHOSPHATE ION, ...
Authors:Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J.
Deposit date:2016-07-05
Release date:2017-07-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus
Sci Rep, 7, 2017
6JI1
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BU of 6ji1 by Molmil
Tetrameric PepTSo2 incorporated in salipro nano particle
Descriptor: Proton:oligopeptide symporter POT family
Authors:Kawamoto, A, Matoba, K, Takagi, J.
Deposit date:2019-02-19
Release date:2019-05-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for oligomerization of the prokaryotic peptide transporter PepTSo2.
Acta Crystallogr.,Sect.F, 75, 2019
3GHM
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BU of 3ghm by Molmil
Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A disintegrin and metalloproteinase with thrombospondin motifs 13, ...
Authors:Akiyama, M, Takeda, S, Kokame, K, Takagi, J, Miyata, T.
Deposit date:2009-03-04
Release date:2009-10-27
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
To be Published
3GHN
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BU of 3ghn by Molmil
Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A disintegrin and metalloproteinase with thrombospondin motifs 13, ...
Authors:Akiyama, M, Takeda, S, Kokame, K, Takagi, J, Miyata, T.
Deposit date:2009-03-04
Release date:2009-10-27
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
To be Published
5GIS
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BU of 5gis by Molmil
Crystal structure of a Fab fragment with its ligand peptide
Descriptor: Heavy chain of Fab fragment, Light chain of Fab fragment, SULFATE ION, ...
Authors:Kitago, Y, Kaneko, K.K, Ogasawara, S, Kato, Y, Takagi, J.
Deposit date:2016-06-24
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural basis for multi-specific peptide recognition by the anti-IDH1/2 monoclonal antibody, MsMab-1.
Biochem. Biophys. Res. Commun., 478, 2016
5GIR
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BU of 5gir by Molmil
Crystal structure of a Fab fragment with its ligand peptide
Descriptor: 1,2-ETHANEDIOL, Heavy chain of Fab fragment, LYS-PRO-ILE-ILE-ILE-GLY-SER-HIS-ALA-TYR-GLY-ASP, ...
Authors:Kitago, Y, Kaneko, K.K, Ogasawara, S, Kato, Y, Takagi, J.
Deposit date:2016-06-24
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural basis for multi-specific peptide recognition by the anti-IDH1/2 monoclonal antibody, MsMab-1.
Biochem. Biophys. Res. Commun., 478, 2016
5GJE
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BU of 5gje by Molmil
Three-dimensional reconstruction of human LRP6 ectodomain complexed with Dkk1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Matoba, K, Mihara, E, Tamura-Kawakami, K, Hirai, H, Thompson, S, Iwasaki, K, Takagi, J.
Deposit date:2016-06-29
Release date:2017-01-18
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (21 Å)
Cite:Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1
Cell Rep, 18, 2017
4YO0
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BU of 4yo0 by Molmil
Crystal structure of monoclonal anti-human podoplanin antibody NZ-1 with bound PA peptide
Descriptor: 1,2-ETHANEDIOL, Heavy chain of antigen binding fragment, Fab, ...
Authors:Fujii, Y, Kitago, Y, Arimori, T, Takagi, J.
Deposit date:2015-03-11
Release date:2016-03-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Tailored placement of a turn-forming PA tag into the structured domain of a protein to probe its conformational state
J.Cell.Sci., 129, 2016
4YNY
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BU of 4yny by Molmil
Crystal structure of monoclonal anti-human podoplanin antibody NZ-1
Descriptor: Heavy chain of antigen binding fragment, Fab, Light chain of antigen binding fragment
Authors:Fujii, Y, Kitago, Y, Arimori, T, Takagi, J.
Deposit date:2015-03-11
Release date:2016-03-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.584 Å)
Cite:Tailored placement of a turn-forming PA tag into the structured domain of a protein to probe its conformational state
J.Cell.Sci., 129, 2016
3NKM
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BU of 3nkm by Molmil
Crystal structure of mouse autotaxin
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKN
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BU of 3nkn by Molmil
Crystal structure of mouse autotaxin in complex with 14:0-LPA
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKQ
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BU of 3nkq by Molmil
Crystal structure of mouse autotaxin in complex with 18:3-LPA
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E,12Z,15Z)-octadeca-9,12,15-trienoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKO
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BU of 3nko by Molmil
Crystal structure of mouse autotaxin in complex with 16:0-LPA
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKP
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BU of 3nkp by Molmil
Crystal structure of mouse autotaxin in complex with 18:1-LPA
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKR
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BU of 3nkr by Molmil
Crystal structure of mouse autotaxin in complex with 22:6-LPA
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl (4Z,7E,10E,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.704 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
1L0Q
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BU of 1l0q by Molmil
Tandem YVTN beta-propeller and PKD domains from an archaeal surface layer protein
Descriptor: Surface layer protein
Authors:Jing, H, Takagi, J, Liu, J.-H, Lindgren, S, Zhang, R.-G, Joachimiak, A, Wang, J.-H, Springer, T.A.
Deposit date:2002-02-12
Release date:2002-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Archaeal Surface Layer Proteins Contain beta Propeller, PKD, and beta Helix Domains and Are Related to Metazoan Cell Surface Proteins.
Structure, 10, 2002
2DDU
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BU of 2ddu by Molmil
Crystal structure of the third repeat domain of reelin
Descriptor: CALCIUM ION, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Nogi, T, Yasui, N, Takagi, J.
Deposit date:2006-02-03
Release date:2006-09-26
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomography
Embo J., 25, 2006
7CEC
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BU of 7cec by Molmil
Structure of alpha6beta1 integrin in complex with laminin-511
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Arimori, T, Miyazaki, N, Takagi, J.
Deposit date:2020-06-22
Release date:2021-06-23
Last modified:2021-07-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural mechanism of laminin recognition by integrin.
Nat Commun, 12, 2021
7CEA
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BU of 7cea by Molmil
Crystal structure of HUTS-4 Fv-clasp fragment
Descriptor: HUTS-4 VH(S112C)-SARAH, HUTS-4 VL(C87Y)-SARAH(S37C)
Authors:Arimori, T, Takagi, J.
Deposit date:2020-06-22
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural mechanism of laminin recognition by integrin.
Nat Commun, 12, 2021

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PDB entries from 2024-03-27

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