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4XI3
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Estrogen Receptor Alpha Ligand Binding Domain in Complex with Bazedoxifene
Descriptor: Bazedoxifene, Estrogen receptor
Authors:Fanning, S.W, Mayne, C.G, Toy, W, Carlson, K, Greene, B, Nowak, J, Walter, R, Panchamukhi, S, Tajhorshid, E, Nettles, K.W, Chandarlapaty, S, Katzenellenbogen, J, Greene, G.L.
Deposit date:2015-01-06
Release date:2016-01-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.491 Å)
Cite:The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.
Elife, 7, 2018

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