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7M19
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BU of 7m19 by Molmil
SN-407-LRRC8A in MSP1E3D1 lipid nanodiscs (Pose-2)
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 7-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}heptanoic acid, Volume-regulated anion channel subunit LRRC8A
Authors:Kern, D.M, Gerber, E.E, Brohawn, S.G.
Deposit date:2021-03-12
Release date:2021-03-24
Last modified:2022-02-23
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes.
Nat Commun, 13, 2022
7M17
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BU of 7m17 by Molmil
SN-407-LRRC8A in MSP1E3D1 lipid nanodiscs (Pose-1)
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 7-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}heptanoic acid, Volume-regulated anion channel subunit LRRC8A
Authors:Kern, D.M, Gerber, E.E, Brohawn, S.G.
Deposit date:2021-03-12
Release date:2021-03-24
Last modified:2022-02-23
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes.
Nat Commun, 13, 2022
3OEQ
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BU of 3oeq by Molmil
Crystal structure of trimeric frataxin from the yeast Saccharomyces cerevisiae, with full length n-terminus
Descriptor: Frataxin homolog, mitochondrial
Authors:Soderberg, C.A.G, Rajan, S, Gakh, O, Ta, C, Isaya, G, Al-Karadaghi, S.
Deposit date:2010-08-13
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Oligomerization Propensity and Flexibility of Yeast Frataxin Studied by X-ray Crystallography and Small-Angle X-ray Scattering.
J.Mol.Biol., 414, 2011
3OER
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BU of 3oer by Molmil
Crystal structure of trimeric frataxin from the yeast saccharomyces cerevisiae, complexed with cobalt
Descriptor: COBALT (II) ION, Frataxin homolog, mitochondrial
Authors:Soderberg, C.A.G, Rajan, S, Gakh, O, Ta, C, Isaya, G, Al-Karadaghi, S.
Deposit date:2010-08-13
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Oligomerization Propensity and Flexibility of Yeast Frataxin Studied by X-ray Crystallography and Small-Angle X-ray Scattering.
J.Mol.Biol., 414, 2011

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