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1D1H
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BU of 1d1h by Molmil
SOLUTION STRUCTURE OF HANATOXIN 1
Descriptor: HANATOXIN TYPE 1
Authors:Takahashi, H, Kim, J.I, Sato, K, Swartz, K.J, Shimada, I.
Deposit date:1999-09-16
Release date:2000-09-20
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins.
J.Mol.Biol., 297, 2000
8TEO
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BU of 8teo by Molmil
Shaker in low K+ (4mM K+)
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel protein Shaker
Authors:Tan, X, Swartz, K.J.
Deposit date:2023-07-06
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:Eukaryotic Kv channel Shaker inactivates through selectivity filter dilation rather than collapse.
Sci Adv, 9, 2023
8SLX
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BU of 8slx by Molmil
Rat TRPV2 bound with 1 CBD ligand in nanodiscs
Descriptor: SODIUM ION, Transient receptor potential cation channel subfamily V member 2, cannabidiol
Authors:Tan, X, Swartz, K.J.
Deposit date:2023-04-24
Release date:2023-05-31
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Cannabidiol sensitizes TRPV2 channels to activation by 2-APB.
Elife, 12, 2023
8SLY
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BU of 8sly by Molmil
Rat TRPV2 bound with 2 CBD ligands in nanodiscs
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 2, ...
Authors:Tan, X, Swartz, K.J.
Deposit date:2023-04-24
Release date:2023-05-31
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Cannabidiol sensitizes TRPV2 channels to activation by 2-APB.
Elife, 12, 2023
8SD3
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BU of 8sd3 by Molmil
CryoEM structure of rat Kv2.1(1-598) wild type in nanodiscs
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel subfamily B member 1
Authors:Tan, X, Swartz, K.J.
Deposit date:2023-04-06
Release date:2023-09-27
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Inactivation of the Kv2.1 channel through electromechanical coupling.
Nature, 622, 2023
8SDA
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BU of 8sda by Molmil
CryoEM structure of rat Kv2.1(1-598) L403A mutant in nanodiscs
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel subfamily B member 1
Authors:Tan, X, Swartz, K.J.
Deposit date:2023-04-06
Release date:2023-09-27
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Inactivation of the Kv2.1 channel through electromechanical coupling.
Nature, 622, 2023
1LA4
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BU of 1la4 by Molmil
Solution Structure of SGTx1
Descriptor: SGTx1
Authors:Lee, C.W, Roh, S.H, Kim, S, Endoh, H, Kodera, Y, Maeda, T, Swartz, K.J, Kim, J.I.
Deposit date:2002-03-28
Release date:2003-11-11
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution Structure and Functional Characterization of SGTx1, a Modifier of Kv2.1 Channel Gating
Biochemistry, 43, 2004
6EBM
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BU of 6ebm by Molmil
The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, transmembrane domain of subunit alpha
Descriptor: Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera
Authors:Matthies, D, Bae, C, Fox, T, Bartesaghi, A, Subramaniam, S, Swartz, K.J.
Deposit date:2018-08-06
Release date:2018-08-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6EBK
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BU of 6ebk by Molmil
The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, Voltage-gated potassium channel subunit beta-2
Authors:Matthies, D, Bae, C, Fox, T, Bartesaghi, A, Subramaniam, S, Swartz, K.J.
Deposit date:2018-08-06
Release date:2018-08-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6EBL
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BU of 6ebl by Molmil
The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, cytosolic domain
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, Voltage-gated potassium channel subunit beta-2
Authors:Matthies, D, Bae, C, Fox, T, Bartesaghi, A, Subramaniam, S, Swartz, K.J.
Deposit date:2018-08-06
Release date:2018-08-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
2N9Z
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BU of 2n9z by Molmil
Solution structure of K1 lobe of double-knot toxin
Descriptor: Tau-theraphotoxin-Hs1a
Authors:Bae, C, Anselmi, C, Kalia, J, Jara-Oseguera, A, Schwieters, C.D, Krepkiy, D, Lee, C.W, Kim, E.H, Kim, J.I, Faraldo-Gomez, J.D, Swartz, K.J.
Deposit date:2015-12-16
Release date:2016-03-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin
Elife, 5, 2016
2NAJ
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BU of 2naj by Molmil
Solution structure of K2 lobe of double-knot toxin
Descriptor: Tau-theraphotoxin-Hs1a
Authors:Bae, C, Anselmi, C, Kalia, J, Jara-Oseguera, A, Schwieters, C.D, Krepkiy, D, Lee, C.W, Kim, E.H, Kim, J.I, Faraldo-Gomez, J.D, Swartz, K.J.
Deposit date:2016-01-04
Release date:2016-03-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin
Elife, 5, 2016
7SIP
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BU of 7sip by Molmil
Structure of shaker-IR
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel protein Shaker
Authors:Tan, X, Bae, C, Stix, R, Fernandez, A.I, Huffer, K, Chang, T, Jiang, J, Faraldo-Gomez, J.D, Swartz, K.J.
Deposit date:2021-10-14
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the Shaker Kv channel and mechanism of slow C-type inactivation.
Sci Adv, 8, 2022
7SJ1
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BU of 7sj1 by Molmil
Structure of shaker-W434F
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel protein Shaker
Authors:Tan, X, Bae, C, Stix, R, Fernandez, A.I, Huffer, K, Chang, T, Jiang, J, Faraldo-Gomez, J.D, Swartz, K.J.
Deposit date:2021-10-15
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of the Shaker Kv channel and mechanism of slow C-type inactivation.
Sci Adv, 8, 2022
8DFL
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BU of 8dfl by Molmil
Structure of human Kv1.3 with A0194009G09 nanobodies (alternate conformation)
Descriptor: Nanobody A0194009G09, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion
Authors:Meyerson, J.R, Selvakumar, P.
Deposit date:2022-06-22
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators
Nat Commun, 13, 2022
1KOZ
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BU of 1koz by Molmil
SOLUTION STRUCTURE OF OMEGA-GRAMMOTOXIN SIA
Descriptor: Voltage-dependent Channel Inhibitor
Authors:Takeuchi, K, Park, E.J, Lee, C.W, Kim, J.I, Takahashi, H, Swartz, K.J, Shimada, I.
Deposit date:2001-12-25
Release date:2002-08-28
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of omega-grammotoxin SIA, a gating modifier of P/Q and N-type Ca(2+) channel.
J.Mol.Biol., 321, 2002
1S6X
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BU of 1s6x by Molmil
Solution structure of VSTx
Descriptor: KvAP CHANNEL
Authors:Jung, H.J, Eu, Y.J, Kim, J.I.
Deposit date:2004-01-28
Release date:2005-03-22
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure and lipid membrane partitioning of VSTx1, an inhibitor of the KvAP potassium channel.
Biochemistry, 44, 2005
2WH9
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BU of 2wh9 by Molmil
Solution structure of GxTX-1E
Descriptor: GUANGXITOXIN-1EGXTX-1E
Authors:Lee, S.K, Jung, H.H, Lee, J.Y, Lee, C.W, Kim, J.I.
Deposit date:2009-05-02
Release date:2010-05-26
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution Structure of Gxtx-1E, a High Affinity Tarantula Toxin Interacting with Voltage Sensors in Kv2.1 Potassium Channels.
Biochemistry, 49, 2010
7SSZ
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BU of 7ssz by Molmil
Structure of human Kv1.3 with A0194009G09 nanobodies
Descriptor: Nanobody A0194009G09, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion
Authors:Meyerson, J.R, Selvakumar, P.
Deposit date:2021-11-11
Release date:2022-06-29
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
7SSY
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BU of 7ssy by Molmil
Structure of human Kv1.3 (alternate conformation)
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion
Authors:Meyerson, J.R, Selvakumar, P.
Deposit date:2021-11-11
Release date:2022-06-29
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
7SSV
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BU of 7ssv by Molmil
Structure of human Kv1.3 with Fab-ShK fusion
Descriptor: Fab-ShK fusion, heavy chain, light chain, ...
Authors:Meyerson, J.R, Selvakumar, P, Smider, V, Huang, R.
Deposit date:2021-11-11
Release date:2022-06-29
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
7SSX
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BU of 7ssx by Molmil
Structure of human Kv1.3
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, Green fluorescent protein fusion
Authors:Meyerson, J.R, Selvakumar, P.
Deposit date:2021-11-11
Release date:2022-06-29
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
6AH5
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BU of 6ah5 by Molmil
Structure of human P2X3 receptor in complex with ATP and Mg2+ ion
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Hattori, M.
Deposit date:2018-08-16
Release date:2019-06-12
Last modified:2020-12-23
Method:X-RAY DIFFRACTION (3.819 Å)
Cite:Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP.
Elife, 8, 2019
6AH4
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BU of 6ah4 by Molmil
Structure of human P2X3 receptor in complex with ATP and Ca2+ ion
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Hattori, M.
Deposit date:2018-08-16
Release date:2019-06-12
Last modified:2020-12-23
Method:X-RAY DIFFRACTION (3.296 Å)
Cite:Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP.
Elife, 8, 2019

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