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3PSN
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CRYSTAL STRUCTURE OF MOUSE VPS29 COMPLEXED WITH MN2+
Descriptor:Vacuolar protein sorting-associated protein 29, MANGANESE (II) ION
Authors:Swarbrick, J., Shaw, D., Chhabra, S., Ghai, R., Valkov, E., Norwood, S., Collins, B.
Deposit date:2010-12-02
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography
To be Published
3PSO
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CRYSTAL STRUCTURE OF MOUSE VPS29 COMPLEXED WITH ZN2+
Descriptor:Vacuolar protein sorting-associated protein 29, ZINC ION
Authors:Swarbrick, J., Shaw, D., Chhabra, S., Ghai, R., Valkov, E., Norwood, S., Collins, B.
Deposit date:2010-12-02
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography
To be Published
2A05
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THE CYSTEINE-RICH SECRETORY PROTEIN DOMAIN OF TPX-1 IS RELATED TO ION CHANNEL TOXINS AND REGULATES RYANODINE RECEPTOR CA2+ SIGNALING
Descriptor:Cysteine-rich secretory protein-2
Authors:Gibbs, G.M., Scanlon, M.J., Swarbrick, J., Curtis, S., Dulhunty, A.F., O'Bryan, M.K.
Deposit date:2005-06-15
Release date:2006-01-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling.
J.Biol.Chem., 281, 2006
4AD6
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SYNTHESIS AND SAR OF GUANINE BASED ANALOGUES FOR HPPK INHIBITORS
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 7-(2-HYDROXYETHYL)-8-MERCAPTOGUANINE
Authors:Chhabra, S., Peat, T.S., Swarbrick, J.
Deposit date:2011-12-22
Release date:2013-01-16
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Exploring the Chemical Space Around 8-Mercaptoguanine as a Route to New Inhibitors of the Folate Biosynthesis Enzyme Hppk.
Plos One, 8, 2013
2N1T
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DYNAMIC BINDING MODE OF A SYNAPTOTAGMIN-1-SNARE COMPLEX IN SOLUTION
Descriptor:Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25, ...
Authors:Brewer, K., Bacaj, T., Cavalli, A., Camilloni, C., Swarbrick, J., Liu, J., Zhou, A., Zhou, P., Barlow, N., Xu, J., Seven, A., Prinslow, E., Voleti, R., Haussinger, D., Bonvin, A., Tomchick, D., Vendruscolo, M., Graham, B., Sudhof, T., Rizo, J.
Deposit date:2015-04-21
Release date:2015-06-03
Last modified:2015-07-22
Method:SOLUTION NMR
Cite:Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution.
Nat.Struct.Mol.Biol., 22, 2015
2M32
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ALPHA-1 INTEGRIN I-DOMAIN IN COMPLEX WITH GLOGEN TRIPLE HELICAL PEPTIDE
Descriptor:Integrin alpha-1, GLOGEN peptide, MAGNESIUM ION
Authors:Chin, Y., Headey, S., Mohanty, B., McEwan, P., Swarbrick, J., Mulhern, T., Emsley, J., Simpson, J., Scanlon, M.
Deposit date:2013-01-07
Release date:2013-11-06
Last modified:2014-02-12
Method:SOLUTION NMR
Cite:The Structure of Integrin alpha 1I Domain in Complex with a Collagen-mimetic Peptide.
J.Biol.Chem., 288, 2013
4TMF
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CRYSTAL STRUCTURE OF HUMAN CD38 IN COMPLEX WITH HYDROLYSED COMPOUND JMS713
Descriptor:ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, 5-O-[(R)-{[(S)-[4-(8-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)butoxy](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranose
Authors:Zhang, H., Swarbrick, J., Potter, B., Hao, Q.
Deposit date:2014-06-01
Release date:2015-05-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Cyclic adenosine 5'-diphosphate ribose analogs without a "southern" ribose inhibit ADP-ribosyl cyclase-hydrolase CD38.
J.Med.Chem., 57, 2014