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2A6E
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BU of 2a6e by Molmil
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-02
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
7UWE
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BU of 7uwe by Molmil
CryoEM Structure of E. coli Transcription-Coupled Ribonucleotide Excision Repair (TC-RER) complex
Descriptor: DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Hao, Z.T, Grower, M, Bharati, B, Proshkin, S, Epshtein, V, Svetlov, V, Nudler, E, Shamovsky, I.
Deposit date:2022-05-03
Release date:2023-05-31
Last modified:2023-06-07
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:RNA polymerase drives ribonucleotide excision DNA repair in E. coli.
Cell, 186, 2023
7UWH
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BU of 7uwh by Molmil
CryoEM Structure of E. coli Transcription-Coupled Ribonucleotide Excision Repair (TC-RER) complex bound to ribonucleotide substrate
Descriptor: DNA (59-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Hao, Z.T, Grower, M, Bharati, B, Proshkin, S, Epshtein, V, Svetlov, V, Nudler, E, Shamovsky, I.
Deposit date:2022-05-03
Release date:2023-05-31
Last modified:2023-06-07
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:RNA polymerase drives ribonucleotide excision DNA repair in E. coli.
Cell, 186, 2023
2A69
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BU of 2a69 by Molmil
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-02
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
2A68
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BU of 2a68 by Molmil
Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-01
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
7U5C
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BU of 7u5c by Molmil
Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state
Descriptor: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ...
Authors:Cai, S.W, Zinder, J.C, Svetlov, V, Bush, M.W, Nudler, E, Walz, T, de Lange, T.
Deposit date:2022-03-02
Release date:2022-05-18
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Cryo-EM structure of the human CST-Pol alpha /primase complex in a recruitment state.
Nat.Struct.Mol.Biol., 29, 2022
1TJL
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BU of 1tjl by Molmil
Crystal structure of transcription factor DksA from E. coli
Descriptor: DnaK suppressor protein, ZINC ION
Authors:Perederina, A, Svetlov, V, Vassylyeva, M.N, Artsimovitch, I, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-06-06
Release date:2004-09-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Regulation through the secondary channel--structural framework for ppGpp-DksA synergism during transcription
Cell(Cambridge,Mass.), 118, 2004
2EUL
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BU of 2eul by Molmil
Structure of the transcription factor Gfh1.
Descriptor: ZINC ION, anti-cleavage anti-GreA transcription factor Gfh1
Authors:Symersky, J, Perederina, A, Vassylyeva, M.N, Svetlov, V, Artsimovitch, I, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-10-28
Release date:2005-11-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Regulation through the RNA Polymerase Secondary Channel: STRUCTURAL AND FUNCTIONAL VARIABILITY OF THE COILED-COIL TRANSCRIPTION FACTORS.
J.Biol.Chem., 281, 2006
2OUG
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BU of 2oug by Molmil
Crystal structure of the RfaH transcription factor at 2.1A resolution
Descriptor: Transcriptional activator rfaH
Authors:Vassylyev, D.G, Vassylyeva, M.N, Svetlov, V, Artsimovitch, I.
Deposit date:2007-02-10
Release date:2007-05-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for converting a general transcription factor into an operon-specific virulence regulator.
Mol.Cell, 26, 2007
2P4V
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BU of 2p4v by Molmil
Crystal structure of the transcript cleavage factor, GreB at 2.6A resolution
Descriptor: Transcription elongation factor greB
Authors:Vassylyeva, M.N, Svetlov, V, Dearborn, A.D, Klyuyev, S, Artsimovitch, I, Vassylyev, D.G.
Deposit date:2007-03-13
Release date:2008-01-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The carboxy-terminal coiled-coil of the RNA polymerase beta'-subunit is the main binding site for Gre factors.
Embo Rep., 8, 2007
2BE5
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BU of 2be5 by Molmil
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with inhibitor tagetitoxin
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Vassylyev, D.G, Svetlov, V, Vassylyeva, M.N, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Artsimovitch, I, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-10-22
Release date:2005-11-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for transcription inhibition by tagetitoxin
Nat.Struct.Mol.Biol., 12, 2005
4WQS
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BU of 4wqs by Molmil
Thermus thermophilus RNA polymerase backtracked complex
Descriptor: DNA (28-MER), DNA (5'-D(P*GP*TP*AP*GP*CP*TP*TP*GP*TP*GP*GP*TP*AP*GP*TP*GP*AP*CP*GP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Murayama, Y, Sekine, S, Yokoyama, S.
Deposit date:2014-10-22
Release date:2015-02-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (4.306 Å)
Cite:The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions.
Mol.Cell, 57, 2015
4WQT
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BU of 4wqt by Molmil
Thermus thermophilus RNA polymerase complexed with an RNA cleavage stimulating factor (a GreA/Gfh1 chimeric protein)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Murayama, Y, Sekine, S, Yokoyama, S.
Deposit date:2014-10-22
Release date:2015-02-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions.
Mol.Cell, 57, 2015
8SVF
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BU of 8svf by Molmil
BAP1/ASXL1 bound to the H2AK119Ub Nucleosome
Descriptor: DNA/RNA (187-MER), DNA/RNA (327-MER), Histone H2A type 1, ...
Authors:Thomas, J.F, Valencia-Sanchez, M.I, Armache, K.-J.
Deposit date:2023-05-16
Release date:2023-08-30
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1.
Sci Adv, 9, 2023
7EGT
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BU of 7egt by Molmil
The crystal structure of the C-terminal domain of T. thermophilus UvrD complexed with the N-terminal domain of UvrB
Descriptor: DNA helicase UvrD, UvrABC system protein B
Authors:Zheng, F, Shen, L, Li, L, Zhang, Y.
Deposit date:2021-03-26
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.581 Å)
Cite:Crucial role and mechanism of transcription-coupled DNA repair in bacteria.
Nature, 604, 2022
7EGS
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BU of 7egs by Molmil
The crystal structure of lobe domain of E. coli RNA polymerase complexed with the C-terminal domain of UvrD
Descriptor: DNA helicase II, DNA-directed RNA polymerase subunit beta, GLYCEROL
Authors:Zheng, F, Shen, L, Li, L, Zhang, Y.
Deposit date:2021-03-26
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crucial role and mechanism of transcription-coupled DNA repair in bacteria.
Nature, 604, 2022
6XAV
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BU of 6xav by Molmil
CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex bound with NusG
Descriptor: DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Hao, Z.T, Kim, H.K, Walz, T, Nudler, E.
Deposit date:2020-06-04
Release date:2020-12-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Pre-termination Transcription Complex: Structure and Function.
Mol.Cell, 81, 2021
6XAS
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BU of 6xas by Molmil
CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex
Descriptor: DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Hao, Z.T, Kim, H.K, Walz, T, Nudler, E.
Deposit date:2020-06-04
Release date:2020-12-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Pre-termination Transcription Complex: Structure and Function.
Mol.Cell, 81, 2021
6CDD
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BU of 6cdd by Molmil
Npl4 zinc finger and MPN domains (Chaetomium thermophilum)
Descriptor: Npl4 zinc finger, ZINC ION
Authors:Bodnar, N.O, Rapoport, T.A.
Deposit date:2018-02-08
Release date:2018-07-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.58233714 Å)
Cite:Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4.
Nat. Struct. Mol. Biol., 25, 2018
6CHS
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BU of 6chs by Molmil
Cdc48-Npl4 complex in the presence of ATP-gamma-S
Descriptor: MAGNESIUM ION, Npl4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Kim, K.H, Bodnar, N.O, Walz, T, Rapoport, T.A.
Deposit date:2018-02-22
Release date:2018-07-04
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4.
Nat. Struct. Mol. Biol., 25, 2018
6AWB
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BU of 6awb by Molmil
Structure of 30S ribosomal subunit and RNA polymerase complex in non-rotated state
Descriptor: 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ...
Authors:Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
Deposit date:2017-09-05
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6AWD
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BU of 6awd by Molmil
Structure of 30S (S1 depleted) ribosomal subunit and RNA polymerase complex
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
Deposit date:2017-09-05
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6AWC
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BU of 6awc by Molmil
Structure of 30S ribosomal subunit and RNA polymerase complex in rotated state
Descriptor: 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ...
Authors:Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
Deposit date:2017-09-05
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6VK3
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BU of 6vk3 by Molmil
CryoEM structure of Hrd3/Yos9 complex
Descriptor: Hrd3, Protein OS-9 homolog
Authors:Wu, X, Rapoport, T.A.
Deposit date:2020-01-18
Release date:2020-04-29
Last modified:2020-05-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020
6VJZ
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BU of 6vjz by Molmil
CryoEM structure of Hrd1-Usa1/Der1/Hrd3 complex of the expected topology
Descriptor: Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ...
Authors:Wu, X, Rapoport, T.A.
Deposit date:2020-01-18
Release date:2020-04-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020

 

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