Author results

1DDY
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MOLECULAR RECOGNITION BY THE VITAMIN B12 RNA APTAMER
Descriptor:VITAMIN B12 BINDING RNA, COBALAMIN, METHYLAMINE
Authors:Sussman, D., Nix, J.C., Wilson, C.
Deposit date:1999-11-12
Release date:2000-01-01
Last modified:2012-10-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structural basis for molecular recognition by the vitamin B 12 RNA aptamer.
Nat.Struct.Biol., 7, 2000
1ET4
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CRYSTAL STRUCTURE OF A VITAMIN B12 BINDING RNA APTAMER WITH LIGAND AT 2.3 A
Descriptor:RNA APTAMER, 35-MER, CO-CYANOCOBALAMIN
Authors:Sussman, D., Wilson, C.
Deposit date:2000-04-12
Release date:2000-11-13
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A water channel in the core of the vitamin B(12) RNA aptamer.
Structure Fold.Des., 8, 2000
1U0C
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Y33C MUTANT OF HOMING ENDONUCLEASE I-CREI
Descriptor:5'-D(*GP*CP*TP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*AP*CP*G)-3', 5'-D(*CP*GP*TP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*AP*GP*C)-3', DNA endonuclease I-CreI, ...
Authors:Sussman, D., Chadsey, M., Fauce, S., Engel, A., Bruett, A., Monnat, R., Stoddard, B.L., Seligman, L.M.
Deposit date:2004-07-13
Release date:2004-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Isolation and characterization of new homing endonuclease specificities at individual target site positions.
J.Mol.Biol., 342, 2004
1U0D
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Y33H MUTANT OF HOMING ENDONUCLEASE I-CREI
Descriptor:5'-D(*GP*CP*GP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*CP*GP*C)-3', DNA endonuclease I-CreI
Authors:Sussman, D., Chadsey, M., Fauce, S., Engel, A., Bruett, A., Monnat, R., Stoddard, B.L., Seligman, L.M.
Deposit date:2004-07-13
Release date:2004-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Isolation and characterization of new homing endonuclease specificities at individual target site positions.
J.Mol.Biol., 342, 2004
2I3P
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K28R MUTANT OF HOMING ENDONUCLEASE I-CREI
Descriptor:5'-D(*GP*CP*AP*AP*AP*TP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*AP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*TP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*AP*TP*TP*TP*GP*C)-3', DNA endonuclease I-CreI, ...
Authors:Sussman, D., Rosen, L.
Deposit date:2006-08-20
Release date:2006-09-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Homing endonuclease I-CreI derivatives with novel DNA target specificities.
Nucleic Acids Res., 34, 2006
2FLD
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I-MSOI RE-DESIGNED FOR ALTERED DNA CLEAVAGE SPECIFICITY
Descriptor:5'-D(*GP*CP*AP*GP*AP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*CP*GP*TP*TP*CP*CP*G)-3', 5'-D(*CP*GP*GP*AP*AP*CP*GP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*CP*TP*TP*CP*TP*GP*C)-3', DNA ENDONUCLEASE I-MSOI, ...
Authors:Ashworth, J., Duarte, C.M., Havranek, J.J., Sussman, D., Monnat, R.J., Stoddard, B.L., Baker, D.
Deposit date:2006-01-05
Release date:2006-06-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Computational redesign of endonuclease DNA binding and cleavage specificity.
Nature, 441, 2006
1T9I
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I-CREI(D20N)/DNA COMPLEX
Descriptor:5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*C)-3', DNA endonuclease I-CreI, ...
Authors:Chevalier, B., Sussman, D., Otis, C., Boudreau, D., Turmel, M., Lemieux, C., Stephens, K., Monnat Jr., R.J., Stoddard, B.L.
Deposit date:2004-05-17
Release date:2004-11-16
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Metal-Dependent DNA Cleavage Mechanism of the I-CreI LAGLIDADG Homing Endonuclease.
Biochemistry, 43, 2004
1T9J
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I-CREI(Q47E)/DNA COMPLEX
Descriptor:5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*C)-3', DNA endonuclease I-CreI
Authors:Chevalier, B., Sussman, D., Otis, C., Boudreau, D., Turmel, M., Lemieux, C., Stephens, K., Monnat Jr., R.J., Stoddard, B.L.
Deposit date:2004-05-17
Release date:2004-11-16
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Metal-Dependent DNA Cleavage Mechanism of the I-CreI LAGLIDADG Homing Endonuclease.
Biochemistry, 43, 2004
3E54
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ARCHAEAL INTRON-ENCODED HOMING ENDONUCLEASE I-VDI141I COMPLEXED WITH DNA
Descriptor:RRNA intron-encoded endonuclease, DNA (5'-D(*DCP*DTP*DGP*DAP*DCP*DTP*DCP*DTP*DCP*DTP*DTP*DAP*DA)-3'), DNA (5'-D(P*DGP*DGP*DTP*DAP*DGP*DCP*DCP*DAP*DA)-3'), ...
Authors:Nomura, N., Nomura, Y., Sussman, D., Stoddard, B.L.
Deposit date:2008-08-13
Release date:2008-12-30
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Recognition of a common rDNA target site in archaea and eukarya by analogous LAGLIDADG and His-Cys box homing endonucleases
Nucleic Acids Res., 36, 2008
1F27
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CRYSTAL STRUCTURE OF A BIOTIN-BINDING RNA PSEUDOKNOT
Descriptor:RNA (5'-R(*AP*CP*CP*GP*UP*CP*AP*GP*AP*GP*GP*AP*CP*AP*CP*GP*GP*UP*U)-3'), RNA (5'-R(*AP*AP*AP*AP*AP*GP*UP*CP*CP*UP*C)-3'), MAGNESIUM ION, ...
Authors:Nix, J., Sussman, D., Wilson, C.
Deposit date:2000-05-23
Release date:2000-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The 1.3 A crystal structure of a biotin-binding pseudoknot and the basis for RNA molecular recognition.
J.Mol.Biol., 296, 2000
2I3Q
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Q44V MUTANT OF HOMING ENDONUCLEASE I-CREI
Descriptor:5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*AP*CP*GP*TP*GP*AP*GP*TP*CP*AP*GP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*AP*CP*TP*CP*AP*CP*GP*TP*CP*GP*TP*TP*TP*TP*GP*C)-3', DNA endonuclease I-CreI, ...
Authors:Rosen, L., Sussman, D.
Deposit date:2006-08-20
Release date:2006-09-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Homing endonuclease I-CreI derivatives with novel DNA target specificities.
Nucleic Acids Res., 34, 2006
3BVQ
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CRYSTAL STRUCTURE OF APO NOTI RESTRICTION ENDONUCLEASE
Descriptor:NotI restriction endonuclease, FE (III) ION, SULFATE ION
Authors:Lambert, A.R., Sussman, D., Shen, B., Stoddard, B.L.
Deposit date:2008-01-07
Release date:2008-01-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding.
Structure, 16, 2008
3C25
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CRYSTAL STRUCTURE OF NOTI RESTRICTION ENDONUCLEASE BOUND TO COGNATE DNA
Descriptor:DNA (5'-D(*DCP*DGP*DGP*DAP*DGP*DGP*DCP*DGP*DCP*DGP*DGP*DCP*DCP*DGP*DCP*DGP*DCP*DCP*DGP*DCP*DCP*DG)-3'), DNA (5'-D(*DCP*DGP*DGP*DCP*DGP*DGP*DCP*DGP*DCP*DGP*DGP*DCP*DCP*DGP*DCP*DGP*DCP*DCP*DTP*DCP*DCP*DG)-3'), NotI restriction endonuclease, ...
Authors:Lambert, A.R., Sussman, D., Shen, B., Stoddard, B.L.
Deposit date:2008-01-24
Release date:2008-02-12
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding.
Structure, 16, 2008
5IYZ
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TUBULIN-MMAE COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Waight, A.B., Bargsten, K., Doronina, S., Steinmetz, M.O., Sussman, D., Prota, A.E.
Deposit date:2016-03-24
Release date:2016-08-17
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics.
Plos One, 11, 2016
5J2T
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TUBULIN-VINBLASTINE COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Waight, A.B., Bargsten, K., Doronina, S., Steinmetz, M.O., Sussman, D., Prota, A.E.
Deposit date:2016-03-30
Release date:2016-08-17
Last modified:2016-08-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics.
Plos One, 11, 2016
5J2U
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TUBULIN-MMAF COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Waight, A.B., Bargsten, K., Doronina, S., Steinmetz, M.O., Sussman, D., Prota, A.E.
Deposit date:2016-03-30
Release date:2016-08-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics.
Plos One, 11, 2016
2EX5
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GROUP I INTRON-ENCODED HOMING ENDONUCLEASE I-CEUI COMPLEXED WITH DNA
Descriptor:I-CeuI DNA target site, complementary strand, DNA endonuclease I-CeuI, ...
Authors:Spiegel, P.C., Stoddard, B.L.
Deposit date:2005-11-07
Release date:2006-05-23
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of I-CeuI homing endonuclease: Evolving asymmetric DNA recognition from a symmetric protein scaffold.
Structure, 14, 2006