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2H4U
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CRYSTAL STRUCTURE OF HUMAN THIOESTERASE SUPERFAMILY MEMBER 2 (CASP TARGET)
Descriptor:Thioesterase superfamily member 2
Authors:Ogg, D.J., Uppenberg, J., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Grasslund, S., Flodin, S., Hammerstrom, M., Hogbom, M., Holmberg-Schiavone, L., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.-G., Weigelt, J., Hallberg, M., Structural Genomics Consortium (SGC)
Deposit date:2006-05-25
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of human thioesterase superfamily member 2
To be Published
2J91
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CRYSTAL STRUCTURE OF HUMAN ADENYLOSUCCINATE LYASE IN COMPLEX WITH AMP
Descriptor:ADENYLOSUCCINATE LYASE, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
Authors:Stenmark, P., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Magnusdottir, A., Nilsson, M.E., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Uppsten, M., Thorsell, A.G., van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.
Deposit date:2006-11-01
Release date:2006-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Human Adenylosuccinate Lyase
To be Published
2JEO
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CRYSTAL STRUCTURE OF HUMAN URIDINE-CYTIDINE KINASE 1
Descriptor:URIDINE-CYTIDINE KINASE 1
Authors:Kosinska, U., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E.P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Uppsten, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2007-01-18
Release date:2007-01-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Human Uridine-Cytidine Kinase 1
To be Published
2UVQ
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CRYSTAL STRUCTURE OF HUMAN URIDINE-CYTIDINE KINASE 1 IN COMPLEX WITH ADP
Descriptor:URIDINE-CYTIDINE KINASE 1, ADENOSINE-5'-DIPHOSPHATE
Authors:Kosinska, U., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E.P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Uppsten, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2007-03-13
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Human Uridine-Cytidine Kinase 1
To be Published
2UW2
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CRYSTAL STRUCTURE OF HUMAN RIBONUCLEOTIDE REDUCTASE SUBUNIT R2
Descriptor:RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 SUBUNIT, FE (III) ION
Authors:Welin, M., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Kotenyova, T., Magnusdottir, A., Moche, M., Nilsson-Ehle, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Stenmark, P., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.
Deposit date:2007-03-16
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Human Ribonucleotide Reductase Subunit R2
To be Published
2VD6
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HUMAN ADENYLOSUCCINATE LYASE IN COMPLEX WITH ITS SUBSTRATE N6-(1,2- DICARBOXYETHYL)-AMP, AND ITS PRODUCTS AMP AND FUMARATE.
Descriptor:ADENYLOSUCCINATE LYASE, ADENOSINE MONOPHOSPHATE, FUMARIC ACID, ...
Authors:Stenmark, P., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2007-09-30
Release date:2007-10-23
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human Adenylosuccinate Lyase in Complex with its Substrate N6-(1,2-Dicarboxyethyl)-AMP, and its Products AMP and Fumarate.
To be Published
1XG5
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STRUCTURE OF HUMAN PUTATIVE DEHYDROGENASE MGC4172 IN COMPLEX WITH NADP
Descriptor:ARPG836, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETIC ACID
Authors:Kavanagh, K., Ng, S., Sharma, S., Vedadi, M., von Delft, F., Walker, J.R., dhe Paganon, S., Bray, J., Oppermann, U., Edwards, A., Arrowsmith, C., Sundstrom, M., Structural Genomics Consortium (SGC)
Deposit date:2004-09-16
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structural Genomics Consortium: Structure of the putative human dehydrogenase MGC4172
To be Published
2A98
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN INOSITOL 1,4,5-TRISPHOSPHATE 3-KINASE C
Descriptor:Inositol 1,4,5-trisphosphate 3-kinase C, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE
Authors:Hallberg, B.M., Ogg, D., Ehn, M., Graslund, S., Hammarstrom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Persson, C., Sagemark, J., Schuler, H., Stenmark, P., Thorsell, A.-G., Arrowsmith, C., Edwards, A., Sundstrom, M., Weigelt, J., Structural Genomics Consortium (SGC)
Deposit date:2005-07-11
Release date:2005-07-19
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of the catalytic domain of human inositol 1,4,5-trisphosphate 3-kinase C
To be Published
2BT2
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STRUCTURE OF THE REGULATOR OF G-PROTEIN SIGNALING 16
Descriptor:REGULATOR OF G-PROTEIN SIGNALING 16
Authors:Bunkoczi, G., Haroniti, A., Longman, E., Niesen, F., Soundararajan, M., Ball, L.J., von Delft, F., Doyle, D.A., Arrowsmith, C., Edwards, A., Sundstrom, M.
Deposit date:2005-05-25
Release date:2005-06-03
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Diversity in the Rgs Domain and its Interaction with Heterotrimeric G Protein Alpha- Subunits.
Proc.Natl.Acad.Sci.USA, 105, 2008
2BV1
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REGULATOR OF G-PROTEIN SIGNALLING 1 (HUMAN)
Descriptor:REGULATOR OF G-PROTEIN SIGNALLING 1
Authors:Elkins, J.M., Yang, X., Soundararajan, M., Schoch, G.A., Haroniti, A., Sundstrom, M., Edwards, A., Arrowsmith, C., Doyle, D.A.
Deposit date:2005-06-20
Release date:2005-06-27
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc. Natl. Acad. Sci. U.S.A., 105, 2008
2C4K
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CRYSTAL STRUCTURE OF HUMAN PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE- ASSOCIATED PROTEIN 39 (PAP39)
Descriptor:PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE-ASSOCIATED PROTEIN 1, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE
Authors:Kursula, P., Stenmark, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Flodin, S., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Kotenyova, T., Nilsson-Ehle, P., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Nordlund, P.
Deposit date:2005-10-20
Release date:2005-10-24
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of Human Phosphoribosylpyrophosphate Synthetase-Associated Protein 39 (Pap39)
To be Published
2ERY
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THE CRYSTAL STRUCTURE OF THE RAS RELATED PROTEIN RRAS2 (RRAS2) IN THE GDP BOUND STATE
Descriptor:Ras-related protein R-Ras2, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Salah, E., Schoch, G., Turnbull, A., Papagrigoriou, E., Soundararajan, M., Burgess, N., Elkins, J., Gileadi, C., Gileadi, O., von Delft, F., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2005-10-25
Release date:2005-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state
To be Published
2F73
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CRYSTAL STRUCTURE OF HUMAN FATTY ACID BINDING PROTEIN 1 (FABP1)
Descriptor:Fatty acid-binding protein, liver
Authors:Kursula, P., Thorsell, A.G., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Flodin, S., Graslund, S., Hammarstrom, M., Holmberg Schiavone, L., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., van den Berg, S., Weigelt, J., Hallberg, B.M., Structural Genomics Consortium (SGC)
Deposit date:2005-11-30
Release date:2005-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human FABP1
To be Published
2FIM
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STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN TUBBY-LIKE PROTEIN 1
Descriptor:Tubby related protein 1, 3-(N,N-DIMETHYLOCTYLAMMONIO)PROPANESULFONATE, SULFATE ION
Authors:Hallberg, B.M., Ogg, D., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Flodin, S., Graslund, S., Hammarstrom, M., Hogbom, M., Holmberg-Schiavone, L., Kotenyova, T., Kursula, P., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Persson, C.
Deposit date:2005-12-29
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the C-terminal domain of Human Tubby-like protein 1
To be published
2FV8
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THE CRYSTAL STRUCTURE OF RHOB IN THE GDP-BOUND STATE
Descriptor:Rho-related GTP-binding protein RhoB, GUANOSINE-5'-DIPHOSPHATE
Authors:Turnbull, A.P., Soundararajan, M., Smee, C., Johansson, C., Schoch, G., Gorrec, F., Bray, J., Papagrigoriou, E., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2006-01-30
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of RhoB in the GDP-bound state
To be Published
2GJS
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THE CRYSTAL STRUCTURE OF HUMAN RRAD IN COMPLEX WITH GDP
Descriptor:GTP-binding protein RAD, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Turnbull, A.P., Yang, X., Soundararajan, M., Schoch, G., Debreczeni, J., Elkins, J.M., Gileadi, C., Berridge, G., Pantic, N., Burgess, N., Smee, C.E.A., Bray, J., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2006-03-31
Release date:2006-04-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of human RRAD in complex with GDP
To be Published
2GK9
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HUMAN PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE, TYPE II, GAMMA
Descriptor:phosphatidylinositol-4-phosphate 5-kinase, type II, gamma
Authors:Uppenberg, J., Hogbom, M., Ogg, D., Arrowsmith, C., Berglund, H., Collins, R., Ehn, M., Flodin, S., Flores, A., Graslund, S., Holmberg-Schiavone, L., Edwards, A., Hammarstrom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Hallberg, B.M., Structural Genomics Consortium (SGC)
Deposit date:2006-03-31
Release date:2006-05-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma
To be Published
2GTP
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CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS1 AND ACTIVATED GI ALPHA 1
Descriptor:Guanine nucleotide-binding protein G(i), alpha-1 subunit, Regulator of G-protein signaling 1, ...
Authors:Soundararajan, M., Turnbull, A.P., Ugochukwu, E., Gorrec, F., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-04-28
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2GUU
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CRYSTAL STRUCTURE OF PLASMODIUM VIVAX OROTIDINE 5-MONOPHOSPHATE DECARBOXYLASE WITH 6-AZA-UMP BOUND
Descriptor:ODcase, 6-AZA URIDINE 5'-MONOPHOSPHATE
Authors:Dong, A., Lew, J., Zhao, Y., Sundararajan, E., Wasney, G., Vedadi, M., Koeieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Pai, E.F., Kotra, L., Bochkarev, A., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2006-05-01
Release date:2006-05-16
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structure of Plasmodium vivax orotidine 5-monophosphate decarboxylase with 6-aza-UMP bound
To be Published
2H01
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PY00414- PLASMODIUM YOELII THIOREDOXIN PEROXIDASE I
Descriptor:2-CYS PEROXIREDOXIN
Authors:Artz, J., Qiu, W., Min, J.R., Dong, A., Lew, J., Melone, M., Alam, Z., Weigelt, J., Sundstrom, M., Edwards, A.M., Arrowsmith, C.H., Bochkarev, A., Hui, R., Structural Genomics Consortium (SGC)
Deposit date:2006-05-12
Release date:2006-05-30
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of PY00414 - a Plasmodium yoelii thioredoxin peroxidase I
To be Published
2I59
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SOLUTION STRUCTURE OF RGS10
Descriptor:Regulator of G-protein signaling 10
Authors:Fedorov, O., Higman, V.A., Diehl, A., Leidert, M., Lemak, A., Schmieder, P., Oschkinat, H., Elkins, J., Soundarajan, M., Doyle, D.A., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., Ball, L.J., Structural Genomics Consortium (SGC)
Deposit date:2006-08-24
Release date:2006-10-31
Last modified:2020-02-19
Method:SOLUTION NMR
Cite:Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2I6L
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CRYSTAL STRUCTURE OF HUMAN MITOGEN ACTIVATED PROTEIN KINASE 6 (MAPK6)
Descriptor:Mitogen-activated protein kinase 6
Authors:Filippakopoulos, P., Turnbull, A.P., Savitsky, P., Fedorov, O., Berridge, G., Das, S., Elkins, J., Soundararajan, M., Yang, X.W., Doyle, D., Papagrigoriou, E., Pike, A.C.W., Bunkonczi, G., Ugochukwu, E., Debreczeni, J., von Delft, F., Edwards, A., Arrowsmith, C., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2006-08-29
Release date:2006-09-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of the Human Mitogen Activated Protein Kinase 6
To be Published
2IG7
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CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE B
Descriptor:Choline/ethanolamine kinase, UNKNOWN ATOM OR ION
Authors:Rabeh, W.M., Tempel, W., Nedyalkova, L., Wasney, G., Landry, R., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2006-09-22
Release date:2006-10-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Human Choline Kinase B
To be Published
2IHB
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CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS10 AND ACTIVATED GI ALPHA 3
Descriptor:Guanine nucleotide-binding protein G(k) subunit alpha, Regulator of G-protein signalling 10, TETRAFLUOROALUMINATE ION, ...
Authors:Soundararajan, M., Turnbull, A.P., Papagrigoriou, E., Pike, A.C.W., Bunkoczi, G., Ugochukwu, E., Gorrec, F., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-09-26
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2IK8
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CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS16 AND ACTIVATED GI ALPHA 1
Descriptor:Guanine nucleotide-binding protein G(i), alpha-1 subunit, Regulator of G-protein signaling 16, ...
Authors:Soundararajan, M., Turnbull, A.P., Papagrigoriou, E., Debreczeni, J., Gorrec, F., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-10-02
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008