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2AS0
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BU of 2as0 by Molmil
Crystal Structure of PH1915 (APC 5817): A Hypothetical RNA Methyltransferase
Descriptor: hypothetical protein PH1915
Authors:Sun, W, Xu, X, Pavlova, M, Edwards, A.M, Joachimiak, A, Savchenko, A, Christendat, D, Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-08-22
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of a novel SAM-dependent methyltransferase PH1915 from Pyrococcus horikoshii.
Protein Sci., 14, 2005
3GGO
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BU of 3ggo by Molmil
Crystal structure of prephenate dehydrogenase from A. aeolicus with HPP and NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, Prephenate dehydrogenase
Authors:Sun, W, Shahinas, D, Christendat, D.
Deposit date:2009-03-01
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Crystal Structure of Aquifex aeolicus Prephenate Dehydrogenase Reveals the Mode of Tyrosine Inhibition.
J.Biol.Chem., 284, 2009
3GGP
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BU of 3ggp by Molmil
Crystal structure of prephenate dehydrogenase from A. aeolicus in complex with hydroxyphenyl propionate and NAD+
Descriptor: CHLORIDE ION, HYDROXYPHENYL PROPIONIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Sun, W, Shahinas, D, Kimber, M.S, Christendat, D.
Deposit date:2009-03-01
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Crystal Structure of Aquifex aeolicus Prephenate Dehydrogenase Reveals the Mode of Tyrosine Inhibition.
J.Biol.Chem., 284, 2009
3GGG
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BU of 3ggg by Molmil
The crystal structure of A. aeolicus prephenate dehydrogenase in complex with tyrosine and NAD+
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Prephenate dehydrogenase, TYROSINE
Authors:Sun, W, Shahinas, D, Christendat, D.
Deposit date:2009-02-27
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The Crystal Structure of Aquifex aeolicus Prephenate Dehydrogenase Reveals the Mode of Tyrosine Inhibition.
J.Biol.Chem., 284, 2009
2G5C
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BU of 2g5c by Molmil
Crystal Structure of Prephenate Dehydrogenase from Aquifex aeolicus
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, prephenate dehydrogenase
Authors:Sun, W, Singh, S, Zhang, R, Turnbull, J.L, Christendat, D.
Deposit date:2006-02-22
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Prephenate Dehydrogenase from Aquifex aeolicus: Insights into the Catalytic Mechanism
J.Biol.Chem., 281, 2006
4KK1
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BU of 4kk1 by Molmil
Crystal Structure of TSC1 core domain from S. pombe
Descriptor: Tuberous sclerosis 1 protein homolog
Authors:Sun, W, Zhu, Y, Wang, Z.Z, Zhong, Q, Gao, F, Lou, J.Z, Gong, W.M, Xu, W.Q.
Deposit date:2013-05-05
Release date:2013-07-17
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of the yeast TSC1 core domain and implications for tuberous sclerosis pathological mutations.
Nat Commun, 4, 2013
4KK0
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BU of 4kk0 by Molmil
Crystal Structure of TSC1 core domain from S. pombe
Descriptor: Tuberous sclerosis 1 protein homolog
Authors:Sun, W, Zhu, Y, Wang, Z.Z, Zhong, Q, Gao, F, Lou, J.Z, Gong, W.M, Xu, W.Q.
Deposit date:2013-05-05
Release date:2013-07-17
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the yeast TSC1 core domain and implications for tuberous sclerosis pathological mutations.
Nat Commun, 4, 2013
6JE9
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BU of 6je9 by Molmil
Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers
Descriptor: AcrIIC3, CRISPR-associated endonuclease Cas9, sgRNA
Authors:Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
Deposit date:2019-02-04
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6JE4
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BU of 6je4 by Molmil
Crystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomers
Descriptor: 1,2-ETHANEDIOL, AcrIIC3, CRISPR-associated endonuclease Cas9, ...
Authors:Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
Deposit date:2019-02-04
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.069 Å)
Cite:Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6JDQ
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BU of 6jdq by Molmil
Crystal structure of Nme1Cas9 in complex with sgRNA
Descriptor: CRISPR-associated endonuclease Cas9, sgRNA
Authors:Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
Deposit date:2019-02-02
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6JDV
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BU of 6jdv by Molmil
Crystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in catalytic state
Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, MAGNESIUM ION, ...
Authors:Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
Deposit date:2019-02-02
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6JE3
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BU of 6je3 by Molmil
Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) with 5 nt overhang
Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, non-target DNA strand, ...
Authors:Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
Deposit date:2019-02-03
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.931 Å)
Cite:Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6JFU
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BU of 6jfu by Molmil
Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM)
Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, non-target strand, ...
Authors:Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
Deposit date:2019-02-12
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
5YDE
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BU of 5yde by Molmil
Crystal structure of a disease-related gene, hCDC73(1-111)
Descriptor: Parafibromin
Authors:Sun, W, Kuang, X.L, Liu, Y.P, Tian, L.F, Yan, X.X, Xu, W.Q.
Deposit date:2017-09-13
Release date:2017-12-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.023 Å)
Cite:Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome
Sci Rep, 7, 2017
5YDF
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BU of 5ydf by Molmil
Crystal structure of a disease-related gene, hCDC73(1-100)
Descriptor: Parafibromin
Authors:Sun, W, Kuang, X.L, Liu, Y.P, Tian, L.F, Yan, X.X, Xu, W.Q.
Deposit date:2017-09-13
Release date:2017-12-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome
Sci Rep, 7, 2017
8HNT
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BU of 8hnt by Molmil
Crystal structure of anti-CRISPR protein AcrIIC4 bound to HpaCas9-sgRNA surveillance complex
Descriptor: CRISPR-associated endonuclease Cas9, anti-CRISPR protein AcrIIC4, sgRNA
Authors:Sun, W, Cheng, Z, Wang, Y.
Deposit date:2022-12-08
Release date:2023-07-19
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HNV
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BU of 8hnv by Molmil
CryoEM structure of HpaCas9-sgRNA-dsDNA in the presence of AcrIIC4
Descriptor: CRISPR-associated endonuclease Cas9, anti-CRISPR protein AcrIIC4, non-target strand, ...
Authors:Sun, W, Cheng, Z, Wang, J, Yang, X, Wang, Y.
Deposit date:2022-12-08
Release date:2023-07-19
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HNW
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BU of 8hnw by Molmil
Crystal structure of HpaCas9-sgRNA surveillance complex bound to double-stranded DNA
Descriptor: CRISPR-associated endonuclease Cas9, Non-target strand, Target strand, ...
Authors:Sun, W, Cheng, Z, Wang, Y.
Deposit date:2022-12-08
Release date:2023-07-19
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HNS
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BU of 8hns by Molmil
Crystal structure of an anti-CRISPR protein AcrIIC4 in apo form
Descriptor: GLYCEROL, anti-CRISPR protein AcrIIC4
Authors:Sun, W, Cheng, Z, Yang, J, Wang, Y.
Deposit date:2022-12-08
Release date:2023-07-19
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
6KC7
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BU of 6kc7 by Molmil
Crystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in seed-base paring state
Descriptor: CRISPR-associated endonuclease Cas9, DNA (5'-D(*AP*TP*AP*TP*GP*AP*TP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*TP*CP*AP*TP*AP*TP*GP*TP*AP*AP*AP*GP*TP*T)-3'), ...
Authors:Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
Deposit date:2019-06-27
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6KC8
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BU of 6kc8 by Molmil
Crystal structure of WT Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in post-cleavage state
Descriptor: CRISPR-associated endonuclease Cas9, DNA (5'-D(*AP*TP*AP*TP*GP*AP*TP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*TP*CP*AP*TP*AP*TP*GP*TP*A)-3'), ...
Authors:Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
Deposit date:2019-06-27
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
7D68
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BU of 7d68 by Molmil
Cryo-EM structure of the human glucagon-like peptide-2 receptor-Gs protein complex
Descriptor: Glucagon-like peptide 2 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Sun, W, Chen, L, Zhou, Q, Zhao, L, Zhang, H, Cong, Z, Shen, D, Zhao, F, Zhou, F, Cai, X, Chen, Y, Zhou, Y, Gadgaard, S, van der Velden, W.J, Zhao, S, Jiang, Y, Rosenkilde, M.M, Yang, D, Xu, H.E, Zhang, Y, Wang, M.
Deposit date:2020-09-29
Release date:2020-12-16
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor.
Cell Res., 30, 2020
7YBF
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BU of 7ybf by Molmil
Crystal structure of inner membrane protein Sad1 in complex with histone H2A-H2B
Descriptor: Histone H2B-alpha,Histone H2A-beta, Spindle pole body-associated protein sad1
Authors:Sun, W, Hu, C, Chen, Y.
Deposit date:2022-06-29
Release date:2024-01-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of inner membrane protein Sad1 in complex with histone H2A-H2B
To Be Published
4IC6
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BU of 4ic6 by Molmil
Crystal structure of Deg8
Descriptor: Protease Do-like 8, chloroplastic
Authors:Gong, W, Sun, W, Fan, H, Gao, F, Liu, L.
Deposit date:2012-12-10
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structures of Arabidopsis Deg5 and Deg8 reveal new insights into HtrA proteases
Acta Crystallogr.,Sect.D, 69, 2013
4IC5
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BU of 4ic5 by Molmil
Crystal structure of Deg5
Descriptor: CALCIUM ION, Protease Do-like 5, chloroplastic
Authors:Gong, W, Sun, W, Fan, H, Gao, F, Liu, L.
Deposit date:2012-12-10
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.607 Å)
Cite:The structures of Arabidopsis Deg5 and Deg8 reveal new insights into HtrA proteases
Acta Crystallogr.,Sect.D, 69, 2013

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PDB entries from 2024-03-27

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